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What Is The Difference Between Hepatitis A, B, C, D, E?

Viral InfectionsMrMed

25 May 2022

MrMed

5 Min. Read

Last updated on 05 May 2026

Our liver is one of the most important organs of the body to perform major bodily processes. When such a crucial organ undergoes problems like inflammation, the entire system suffers. The term given for inflammation of the liver is known as hepatitis. It is one of the leading causes of death, more deadly than HIV. 

What Are The 5 Types Of Hepatitis?

The liver can undergo inflammation due to autoimmunity, alcohol consumption, drug abuse, etc. However, hepatitis due to viruses is the most common among them. Hepatitis can be classified as acute and chronic hepatitis depending on its duration and impact on the liver. Different types of hepatitis occur due to viral infections. It is essential to know about the five types of hepatitis because they significantly impact our society. Please keep reading to learn about ABCDE of hepatitis and how they differ from each other.

What is Hepatitis A?

As the name goes, hepatitis A is caused by the hepatitis A virus. This virus is highly concentrated in the stool of the infected person. If someone accidentally comes in contact with this virus, they get affected immediately. This is the most common preventable and curable type of viral hepatitis. It stays for a short time and goes away on its own within a few days.

What is Hepatitis B?

Hepatitis B virus spreads through blood, saliva, tears etc. Still, unlike hepatitis A it is not concentrated in urine, sweat or faeces. One can spread this virus by sharing personal products like toothbrushes, syringes, needles for drug use, etc. This virus can also invade your body if you get tattoos under unhygienic conditions through infected needles.

What is Hepatitis C?

Hepatitis C spreads in a way similar to hepatitis B. It causes the liver to swell and cause cancer or scarring of liver tissues and lead to cirrhosis.

What is Hepatitis D?

Hepatitis D, also referred to as the delta hepatitis, is an infection caused by the hepatitis D virus. Delta hepatitis is an incomplete virus that depends on the hepatitis B virus to replicate and spread. This occurs only in people affected by the hepatitis B virus. To prevent delta hepatitis, you need to take the hepatitis B vaccine.

What is Hepatitis E?

Hepatitis E is a liver infection due to the hepatitis E virus. Quite similar to hepatitis A, it does not result in chronic illness. At present vaccination is not available for this type of liver infection.

Let's Learn The Parameters To Differentiate Between Hepatitis A, B, C, D And E

Although all the types of hepatitis are characterised by liver inflammation, the cause and treatment of liver inflammation differ among different types depending on specific parameters. We will further discuss the criteria that differentiate A, B, C, D and E hepatitis.

How Common Is Hepatitis?

Viral hepatitis is a prominent health issue. It affects millions of people annually and causes significant morbidity and mortality. Hepatitis B and C viruses are the most commonly occurring viral hepatitis. Hepatitis B and C together cause almost 90% of deaths due to viral hepatitis.


What Is Hepatitis A, B, C, D, E Causes?

Hepatitis can have several triggers and root causes. There are various pathways through which the hepatitis virus enters our body. Some types of hepatitis might occur due to accidental consumption of contaminated food or water. In contrast, this may not be a risk factor in other types. Some viruses like hepatitis B may spread due to blood transfusion, but they will not be present in urine, stool or sweat. This virus can also spread from a pregnant mother to the fetus in the womb, and has more than 80% chance of inheriting this disease.

Duration Of Infection:

Not all types of hepatitis infections have the same duration. As we discussed earlier, liver inflammation could be acute or chronic. In acute illness, the patient recovers once and for all, and that’s it. You will not get infected by the same virus again. In the case of chronic hepatitis, the inflammation and infection come once and remain for life. 

If the liver remains inflamed for more than 6 months, it is termed chronic hepatitis. It can cause liver fibrosis, cirrhosis and cancer. Acute liver inflammation stays for a short time and resolves on its own; however, depending on the cause, even acute hepatitis can lead to liver failure.

Prevention Of Hepatitis Infection:

Hepatitis infections, in general, are preventable, and some can be prevented through vaccinations. While vaccines are not readily available for all types of hepatitis, you can easily control the infection by altering your lifestyle. Hygiene is the key to prevention. If you are confident that your drinking water and food are not contaminated, you are good to go. Pay attention to personal hygiene, especially if you stay with an infected person. If you are working in the healthcare field, be extra cautious not to touch blood or body fluids without gloves.

Parameters

Hepatitis A

Hepatitis B

Hepatitis C

Hepatitis D

Hepatitis E

Prevalence  

Common 

Common 

Common  

Rare 

Rare 

Transmission

Fecal-oral route. 

Blood and body fluids.
 

Mother to fetus.

Sexual contact with infected person.

Sharing needles or syringes with an infected person.

Sharing needles, blood transfusion, sexual intercourse.

Fecal-oral route

Duration 

Acute 

Chronic

Chronic

Chronic

Acute

Risk factor

Travel to risk-prone countries.

Lack of sanitation in the surroundings

Domestic contact with the infected person.

Consumption of contaminated foods.

Intravenous drug usage.

Multiple sexual partners.


Frequent or multiple blood transfusions.

Partners of hepatitis B infected people.

Healthcare providers working in infected areas.

Sharing of syringe, toothbrush and needles with the infected person.

Intravenous drug usage.


Frequent blood transfusion.

Organ transplantation.

Contact with mucous.

Contact with infectious blood and dirty needles.

History of infection with hepatitis B.

Sexual intercourse.

Accidental consumption of contaminated water.

Incubation period

14-28 days

30-180 days

2 weeks to 6 months

13 weeks

3-8 weeks

Symptoms 

Jaundice in older children and adults.

No symptoms in immunosuppressed adults.

Loss of appetite, nausea, vomiting

Similar to Hepatitis B

Acute illness.

Complications 

No major complications. However, in very rare cases, it may result in liver failure.

Chronic scarring of liver tissues and liver swelling may result in liver cirrhosis and cancer.

Chronic scarring of liver tissues and liver swelling may result in liver cirrhosis and cancer.

No major complications

No major consequences

Prevention

Vaccination and safe hygienic practices.

Vaccination 

Vaccination against hepatitis A and B is the key.

Get vaccinated for hepatitis B to protect yourself from delta hepatitis.

No vaccination is available. Incorporate safe hygiene and avoid drinking tap water.

Treatment 

Supportive care

Strict no to alcohol.

Regular monitoring.

Antiviral medications.

Liver transplantation.

Infection goes away within weeks. 

Supportive care is necessary.

Similar to hepatitis B.

Supportive care. 

Regular monitoring.

Disclaimer: This content is for informational purposes only and does not replace professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider regarding symptoms, hepatitis risks, vaccination, or treatment options tailored to your health condition.

 

Details about the author of this blog

Dr. Bhairavi S

Dr. Bhairavi S

Writer - Medical Communications

Dr. Bhairavi S, RPh is a dedicated medical writer and Pharm D with over four years of professional experience in healthcare communication. She currently develops medical communications content, focusing on article writing, infographics, and CME materials for a community of 380,000+ doctors, supporting evidence-based clinical education. Previously, she served as Medical Content Writer at MEDICCA PRESS Limited, creating CME modules and scientific newsletters (Jan 2023–Feb 2025), and freelanced on prescribing information and healthcare materials (Aug–Nov 2022). At MrMed (Mar 2021–Apr 2022), she refined her expertise in medical proofreading and content accuracy. She also gained clinical experience as a Clinical Pharmacist intern at SRM Medical College Hospital & Research Centre (Jun 2019–Jun 2020). Dr. Bhairavi excels in manuscript writing, literature reviews, and CME development, and is keen to advance in scientific research and medical writing.

Details about the reviewer

Dr. Tejashwin Adiga

Dr. Tejashwin Adiga

Surgery Resident @ Apollo Hospitals, Chennai

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Tags:

Viral hepatitis
different types of viral hepatitis
hepatitis A
hepatitis B
hepatitis C
hepatitis D
hepatitis E

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