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ACTON PROLONGATUM 60IU INJECTION_100018_1
ACTON PROLONGATUM 60IU INJECTION_100018_3
ACTON PROLONGATUM 60IU INJECTION_100018_2
ACTON PROLONGATUM 60IU INJECTION_100018_1
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Acton Prolongatum 60IU Injection

Prescription Required

cold-chain

Salt Composition : Corticotropin

Manufacturer : FERRING PHARMACEUTICALS

Origin of Medicine : India

MRP: 2355
Price :2120
You Save :235 (10%)

1 Vial(s)

Prepaid Only. Non-Returnable


Introduction to Acton Prolongatum 60iu Injection

Acton prolongatum 60IU injection contains an active component such as Corticotropin. It is a medication primarily used to treat various medical conditions related to the adrenal glands and the production of corticosteroid hormones. This medication manages multiple sclerosis flare-ups, reduces proteinuria in resistant nephrotic syndrome, treats infantile spasms, relieves inflammation and pain in rheumatoid arthritis, addresses systemic lupus erythematosus, treats Addison's disease by replacing deficient hormones, helps adrenal gland function assessment, and supports wound healing.

If you have a known allergy to Acton prolongatum 60IU injection or any of its components, it is important to inform your healthcare provider before starting treatment. It can suppress the immune system, so individuals with systemic fungal infections should not take this medication. Its use might not suit individuals with active systemic viral infections, such as herpes or varicella-zoster virus. It is generally avoided in individuals with skin conditions like widespread psoriasis. This medication should be avoided in individuals with uncontrolled diabetes. Individuals with severe osteoporosis might need to avoid this medication. It is generally recommended to avoid live vaccines while on Acton prolongatum 60IU injection treatment. In both children and older adults, always consult a healthcare provider.


Uses of Acton Prolongatum 60iu Injection

Acton prolongatum 60IU injection is used in the following:

  • Adrenal insufficiency (Addison's disease)
  • Infantile spasms
  • Multiple sclerosis (MS) exacerbations
  • Nephrotic syndrome
  • Rheumatoid arthritis
  • Systemic lupus erythematosus (SLE) flares
  • Eosinophilic conditions
  • Wound healing and tissue repair

Therapeutic Effects of Acton Prolongatum 60iu Injection

Acton prolongatum 60IU injection binds to specific receptors on the adrenal cortex, leading to an increase in the production and release of corticosteroid hormones, most notably cortisol. This increase in cortisol levels regulates various physiological processes, including metabolism, immune response, and stress response. In conditions like adrenal insufficiency (Addison's disease), where the adrenal glands fail to produce adequate cortisol, this therapy helps restore hormone balance, alleviating symptoms associated with cortisol deficiency and maintaining overall physiological stability.


Interaction of Acton Prolongatum 60iu Injection with other drugs

Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Acton prolongatum 60IU injection, reducing effectiveness by causing undesirable side effects. 


More Information about Acton Prolongatum 60iu Injection

  • Store at room temperature, between up to  20°C to 25°C
  • Keep away from moisture, heat, and light.
  • It should not be frozen.
  • Keep away from children and pets.

How to consume Acton Prolongatum 60iu Injection

Acton prolongatum 60IU injection (ACTH) medication can be administered through various routes, including intramuscular (IM) injection, subcutaneous (SC) injection, intravenous (IV) injection, and in some cases, intranasal spray or intradermal injection.. It is essential to follow the healthcare provider's instructions for the correct administration technique, dosage, and frequency to ensure safe and effective use of the medication.


Safety Advices for Acton Prolongatum 60iu Injection

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Pregnancy

  

The use of Acton prolongatum 60IU injection during pregnancy should only be taken after having a consultation with a healthcare provider.be discussed with a healthcare provider.

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Breast Feeding

  

Breastfeeding mothers should consult their healthcare provider before using Acton prolongatum 60IU injection.

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Lungs

  

Consult your healthcare provider if you have a history of lung conditions before using Acton prolongatum 60IU injection.

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Liver

  

Patients with liver dysfunction should consult a healthcare provider before taking Acton prolongatum 60IU injection.

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Alcohol

  

It is generally advisable to avoid excessive alcohol consumption while on Acton prolongatum 60IU injection, as alcohol can interact with the medication and potentially worsen certain side effects

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Driving

  

If you experience any adverse effects that could affect your comfort while driving, it is advisable to avoid taking Acton prolongatum 60IU injection.


Side Effects of Acton Prolongatum 60iu Injection

Acton prolongatum 60IU injection causes some side effects like all medications, although not everyone will experience them. 

Serious

  • Allergic reactions
  • Adrenal suppression
  • Osteoporosis
  • Eye conditions
  • Gastrointestinal issues
  • Cardiovascular effects
  • Metabolic effects
  • Cushing's syndrome

Common

  • Increased appetite
  • Mood changes
  • Fluid retention
  • High blood pressure
  • Increased blood glucose
  • Insomnia
  • Skin changes

Word of Advice

When using Acton prolongatum 60IU injection, it is important to disclose your complete medical history, allergies, and current medications to your healthcare provider. Avoid its abrupt discontinuation. Its effects on infections, bone health, interactions, and conditions like glaucoma need close monitoring. Do not adjust the dosage of this medication without consulting your healthcare provider. Prolonged use of this medication can lead to dependence on corticosteroids. Discuss strategies for gradual dose reduction with your healthcare provider if long-term treatment is necessary. Inform healthcare providers of surgery or procedures, and educate yourself about adrenal crisis management.  Inform your healthcare provider if you are due for vaccinations. Be aware that it can influence other hormones in the body. Inform your healthcare provider about any changes in menstrual cycle, libido, or other hormonal symptoms. Always talk openly with your doctor to ensure you are using it correctly.


FAQs

Q 1. Is it normal to have mood swings while using Acton prolongatum 60IU injection?

Mood changes can occur with Acton prolongatum 60IU injection use. If they are concerned, discuss them with your healthcare provider.

Q 2. Will Acton prolongatum 60IU injection affect my blood pressure?

Yes, Acton prolongatum 60IU injection can lead to high blood pressure. Regular monitoring is important.

Q 3. Can I continue my regular exercise routine while on Acton prolongatum 60IU injection?

Generally, exercise is beneficial, but discuss your exercise plan with your healthcare provider to ensure it suits you.

Q 4. Is Acton prolongatum 60IU injection habit-forming?

While Acton prolongatum 60IU injection isn't habit-forming in the traditional sense, long-term use can lead to dependence on corticosteroids. Follow your healthcare provider's instructions for dosage adjustments.

Q 5. Should I be concerned about my eyes while on Acton prolongatum 60IU injection?

Long-term use might impact your eyes. Discuss any changes in vision with an eye specialist.

Q 6. Is it safe to use Acton prolongatum 60IU injection for an extended period?

Your healthcare provider should carefully monitor the long-term use of Acton prolongatum 60IU injection to manage potential risks.


Fact Box of Acton Prolongatum 60iu Injection

Molecule name:  Corticotropin

Therapeutic class:  Hormonal agent

Pharmacological class: Adrenocorticotropic hormone 

Indications: 

1. Adrenal insufficiency (Addison's disease)

2. Infantile spasms

3. Multiple sclerosis (MS) exacerbations

4. Nephrotic syndrome

5. Rheumatoid arthritis

6. Systemic lupus erythematosus (SLE) flares

7. Eosinophilic conditions

8. Wound healing and tissue repair


References

  1. Gundgurthi, Abhay & Garg, M K & Dutta, M & Pakhetra, R., Intramuscular ACTH stimulation test for assessment of adrenal function. J Assoc Physicians India, 2013, 61, 320-4, https://www.researchgate.net/publication/260003252_Intramuscular_ACTH_stimulation_test_for_assessment_of_adrenal_function  [Accessed on 23 August 2023]
  2. Duchowny MS, Chopra I, Niewoehner J, Wan GJ, Devine B, A systematic literature review and indirect treatment comparison of efficacy of repository Corticotropin injection versus synthetic adrenocorticotropic hormone for infantile spasms, JHEOR, 2021, 8(1), 1-9,  [Accessed on 22nd August 2023] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7839629/pdf/jheor_2021_8_1_18727.
  3. Mallinckrodt ARD Inc, US Food and Drug Administration [Revised on 4/2018] [Accessed on 23rd August 2023],   https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/008372s057lbl.pdf
  4. KD Tripathi, Anterior Pituitary Hormones, Essentials of Medical Pharmacology, 8th Edition, 2019, 257-266.

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