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Akynzeo Capsule
Last updated on 26 Sep 2026 | 08:44 AM (IST)
₹4545
MRP: ₹5625
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1 CAPSULE(s) IN A STRIP
Akynzeo Capsule
Salt Composition
NETUPITANT,PALONOSETRONMarketer
GLENMARK PHARMACEUTICALS LTD
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₹4545
MRP: ₹5,625.00
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Introduction
Akynzeo capsule contains the active ingredients Netupitant and Palonosetron. It is an antiemetic drug belonging to the class of 5-HT3 receptor antagonists. Akynzeo capsule uses in chemotherapy to prevent and treat nausea, vomiting, or sickness caused by cancer treatments such as chemotherapy, radiotherapy, or after surgery. Nausea is characterised by stomach pain and the urge to vomit.
Patients can check the Akynzeo capsule 300mg/0.5mg price or the Glenmark Akynzeo capsule price before purchase. You can also buy Akynzeo capsule online India from registered pharmacies. The Akynzeo 300mg/0.5mg capsule cost may vary depending on location and manufacturer.
The prescribed Akynzeo capsule 300/0.5 dosage is based on the patient’s condition and type of chemotherapy. Akynzeo capsule Netupitant Palonosetron price provides a reference for those seeking treatment. It is particularly recommended as Akynzeo for highly emetogenic chemotherapy.
You can also check for alternatives such as Akynzeo 300mg/0.5mg substitute. The Akynzeo capsule manufacturer in India is Glenmark Pharmaceuticals.
Uses
The Akynzeo Capsule Uses include:
- Postoperative nausea and vomiting.
- Chemotherapy-induced nausea and vomiting.
How Akynzeo Capsule works
It is a type of serotonin receptor antagonist, which works by blocking the action of serotonin in the body that induces nausea and vomiting. The chemotherapeutic trigger zone(CTZ) contains the receptor serotonin, when this CTZ is stimulated, vomiting occurs. It prevents the signals from serotonin and helps to reduce the symptoms of nausea and vomiting.
Interaction of Akynzeo Capsule with other drugs
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products. Certain medications may interact with the Akynzeo capsule and reduce effectiveness by causing undesirable side effects.
Storage conditions
- Store the Akynzeo capsule in the original package at room temperature (25°C). Do not freeze.
- Keep it out of reach from children and pets.
- It is important to get the dose at the scheduled time. If you missed the schedule, contact your doctor and reschedule the dose.
How to take Akynzeo Capsule
The medicine will be prescribed to you by a healthcare professional in a hospital setting. Akynzeo capsule is usually given about 30 minutes before you receive your anti-cancer medicine (chemotherapy) or right before anaesthesia for surgery. If you are taking Akynzeo hard capsules, it should be swallowed whole with a glass of water, with or without food, as directed by your healthcare provider.
Safety Advice for Akynzeo Capsule
Breast Feeding
It is not known if the Akynzeo capsule passes into your breast milk or if it will affect your baby or your breast milk. Please consult your doctor before breastfeeding.
Alcohol
It is unknown whether consuming alcohol interacts with Akynzeo capsule. Please consult your doctor for more advice.
Liver
It is unknown whether Akynzeo capsule can be administered to patients with liver disorders. Inform your physician if you have any liver problems before starting treatment.
Lungs
It is not known whether Akynzeo capsule can be administered to patients with lung problems. Consult your doctor if you have any lung diseases before starting the treatment.
Driving
It is unsafe to drive vehicles or operate heavy machinery after taking Akynzeo capsule because it contains a small amount of alcohol which may cause dizziness and impair your concentration.
Pregnancy
It is unknown whether Akynzeo capsule can be administered during pregnancy. Consult your doctor if you are pregnant or planning for pregnancy during the treatment.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Akynzeo capsule side effects are:
Serious side effects of Akynzeo Capsule are:
- Hives
- Swollen face
- Breathing trouble
- Chest pain
Common side effects of Akynzeo Capsule are:
- Headache
- Fatigue
- Dizziness
- Abdominal pain.
Expert Tips
-
Talk to your physician before taking Akynzeo capsule if you have:
- A history of repeated constipation
- Bowel blockage
- Heart problems
- Imbalance of certain minerals in your blood (e.g., potassium or magnesium)
-
Inform your doctor or nurse if you are taking any medicines that affect your heartbeat, as these could cause heartbeat problems when taken with Akynzeo capsule.
FAQs about Akynzeo Capsule
Q1.
What are the possible side effects of Akynzeo capsule?
It can cause serious allergic reactions like hives, swollen face, breathing trouble, and chest pain. Some common side effects include headache and constipation.
Q2.
When should you take the Akynzeo capsule?
Akynzeo capsules can be taken with or without food with a glass full of water. The first dose of this drug is typically taken before the start of your surgery, chemotherapy, or radiation treatment.
Q3.
What is the mechanism of action of Akynzeo capsule ?
Akynzeo capsule works by blocking the action of a chemical called serotonin, which is involved in causing nausea and vomiting.
Q4.
Who should not take an Akynzeo capsule?
Akynzeo capsule should not be taken by individuals who are allergic to it or its ingredients.
Q5.
What forms does the Akynzeo capsule come in?
Akynzeo capsule is available in the form of an oral tablet.
Q6.
What are the benefits of AKYNZEO?
AKYNZEO capsules effectively prevent nausea and vomiting caused by chemotherapy. It combines two antiemetics to provide long-lasting protection against these side effects, improving patient comfort during cancer treatment.
Q7.
Does AKYNZEO make you sleepy?
AKYNZEO capsules may cause drowsiness in some people as a side effect. However, not everyone experiences this, and it varies from person to person.
Q8.
Is AKYNZEO a steroid?
No, the AKYNZEO capsule is not a steroid. It is a combination of two antiemetic drugs used to prevent nausea and vomiting caused by chemotherapy.
Fact Box of Akynzeo Capsule
|
Molecule name |
Netupitant + Palonosetron |
|
Therapeutic class |
Antiemetics |
|
Pharmacological class |
1. Netupitant- Neurokinin 1 receptor antagonist 2.Palonosetron-5-HT3 receptor antagonist |
|
Indications
|
1. Postoperative nausea and vomiting. 2. Chemotherapy induced nausea and vomiting. |
References
- Accord Healthcare SLU, Electronic medicines compendium (emc), [Revised on Feb 2021] [ Accessed on 01st March 2023], https://www.medicines.org.uk/emc/files/pil.7235.pdf
- Fresenius kabi, US Food and Drug Administration, [Revised on Dec 2018] [Accessed on 01st March 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/208109s001lbl.pdf
- Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Treatment of disorders of bowel motility and water flux, 12th edition, 2011, 1341.
- KD Tripathi, Essentials of Medical Pharmacology, Antiemetic, prokinetic and digestant drugs, 7th edition, 2013, 669.
Disclaimer
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Author Details
Written By
Dr. Vijayalakshmi N.
BDS
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 26 Sep 2026 | 08:44 AM (IST)
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