All Substitutes



Want to know more?
Read Our Editorial Policy

Did you find this information helpful?

14% Off

Anobliss Cream

Prescription Required

Salt Composition : Lidocaine 1.5%,nifedipine 0.3%


Origin of Medicine : India

MRP: 136.68
Price :117
You Save :20 (14%)

1 Tube Of 30gm

Introduction to Anobliss Cream

Anobliss cream cream contains the active component of lidocaine and nifedipine, which belong to the class of local anesthetics and calcium channel blockers, respectively. This combination cream is used in the treatment of anal fissures with a fast healing response. Anal fissures are tears in the lining of the anal canal, often caused by constipation and passing off hard faces. These create spasms that reduce blood flow, preventing the healing of fissures. It also prevents the evolution of acute anal fissure to chronic anal fissure.

Before using this cream, inform your doctor if you have allergies to lignocaine or nifedipine. Also, inform your doctor if you have any underlying disease before using this cream. Give a detailed account of your medical history and medications to your healthcare provider to ensure safe usage of anobliss cream.

Uses of Anobliss Cream

  • Anal fissure

Therapeutic Effects of Anobliss Cream

Anobliss cream contains 1.5% lidocaine, a local anesthetic providing pain relief, and 0.3% nifedipine, a calcium channel blocker that relaxes the smooth muscle around the anal canal, aiding the healing of fissures.

Interaction of Anobliss Cream with other drugs

Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products you take or have taken before taking this medication. Certain medications may interact with anobliss cream and cause undesirable side effects.

More Information about Anobliss Cream

  • Keep anobliss cream away from the sight and reach of children.
  • Store at 2°C to 8°C.
  • Do not use this medicine after the expiry date.

How to consume Anobliss Cream

To properly use anobliss cream, start by washing your hands thoroughly and wearing gloves to minimize the risk of side effects. Lie on your left side, keeping your left leg straight and bending your right leg with your knee raised. Stay relaxed during the process. Apply a pinhead-sized amount of the cream on your finger and gently spread it around the anus and just inside the rectum. After application, remove the gloves and wash your hands again for proper hygiene. Apply twice a day, once in the morning and once at night. Following these steps ensures effective and safe use of the cream for relief and healing.

Safety Advices for Anobliss Cream

Image Not Available  



Anobliss cream cream is safe for use during pregnancy as it does not cause any systemic toxicity. It is also advised for mothers after childbirth to treat fissures near the anus, which may progress to chronic anal fissures. Therefore, it is considered safe for use during pregnancy.

Image Not Available  

Breast Feeding


Anobliss cream is safe for use while breastfeeding as it does not cause any systemic toxicity.

Image Not Available  



It is generally safe to use anobliss cream in lung patients since there is no reported systemic toxicity.

Image Not Available  



It is generally safe to use anobliss cream in liver patients since there is no reported systemic toxicity.

Image Not Available  



Anobliss cream application does not affect alcohol consumption. However, it is not advisable to take alcohol as it can alter bowel movements and prevent your fissure from healing. Consult your doctor for more advice.

Image Not Available  



Anobliss cream has no systemic side effects. Hence, it is safe to drive or operate heavy machines.

Side Effects of Anobliss Cream

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.


  • Severe allergic reactions (rashes, swelling, difficulty breathing and severe dizziness)


  • Irritation in the rectal area

Word of Advice

Anobliss cream is exclusively for topical usage to be applied in the anal passage. Utilize the provided applicator to insert a measured dose of the cream into your back passage. Ensure it does not come into contact with your eyes, mouth, or nose. If accidental contact occurs, rinse the affected area with cold water immediately.

To manage constipation caused by anal fissures, maintain proper hydration by drinking plenty of fluids. Include fiber-rich foods like whole grains, oatmeal, and citrus fruits. Regular exercise is beneficial, and it is advisable not to spend excessive time sitting on the toilet. Pay attention to your body's signals and avoid ignoring the urge to go to the washroom, promoting overall effective treatment and relief.


Q 1. What is anobliss cream?

Anobliss cream is a topical rectal cream used to treat anal fissures. It contains 1.5% lidocaine, providing pain relief, and 0.3% nifedipine, which relaxes the smooth muscles in the anal canal, promoting healing.

Q 2. Is anobliss cream safe during pregnancy and breastfeeding?

Yes, it is considered safe for use during pregnancy and breastfeeding as it does not cause systemic toxicity. However, it is always best to consult your doctor for personalized advice.

Q 3. How often should I apply anobliss cream, and what is the proper application technique?

Apply the anobliss cream twice daily, once in the morning and once at night. While applying, wash your hands thoroughly and wear gloves to minimize the risk of side effects. Use the provided applicator to insert a measured dose into the anal passage. Be cautious to avoid contact with eyes, mouth, or nose. In case of accidental contact, rinse the area with cold water immediately.

Q 4. Can this anobliss cream be used for children?

Topical 0.2% nifedipine with lidocaine 1.5% appears to be an efficient treatment for anal fissures in children, with a significant healing rate and no side effects, following consultation with your healthcare provider.

Q 5. How long does it take to see improvement in anal fissure symptoms after using anobliss cream?

The healing process varies from person to person. While some individuals may experience relief within a few days, others might take longer. It is essential to follow the prescribed application routine of anobliss cream and consult your healthcare provider if you have concerns about the progress.

Fact Box of Anobliss Cream

Molecule Name: Lidocaine + Nifedipine

Therapeutic class: Topical anti-rectal medications

Pharmacological class:     

1. Lidocaine - Local anesthetics

2. Nifedipine - Calcium channel blockers

Indications: Anal fissure


  1. Perrotti P et al., Topical nifedipine with lidocaine ointment vs. active control for treatment of chronic anal fissure: results of a prospective, randomized, double-blind study; Published on Nov 2022; Accessed on 03/11/2023;
  2. Albayati RK et al; Topical combination of Nifedipine with Lidocaine for Anal Fissure Treatment; Indian Journal of Public Health Research and Development; Published on Feb 2019; Accessed date 03/11/2023;
  3. Katsinelos P et al., Aggressive treatment of acute anal fissure with 0.5% nifedipine ointment prevents its evolution to chronicity; World J Gastroenterol; Published on Oct 2006; Accessed on 03/11/2023;
  4. Michigan Medicine, the U.S Food and Drug Administration (FDA); [Revised on March 2017] [Accessed on Nov 2023];
  5. KD Tripathi, Essentials of Medical Pharmacology, Antianginal and other anti-ischaemic drugs, 7th edition, 2013, 547-549.
  6. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Local Anaesthetics, 12th edition, 2011, 572- 573.


MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.

4000+ products

We maintain strict quality controls on all our partner retailers, so that you always get standard quality products.

Secure Payment

100% secure and trusted payment protection

Easy Return

We have a new and dynamic return window policy for medicines and healthcare items. Refer FAQs section for more details.