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Aprefos 150mg Injection
Prescription Required
Salt Composition : Aprepitant
Manufacturer : DELARC PHARMACEUTICALS
Origin of Medicine : India
1 Vial(s)
Introduction to Aprefos 150mg Injection
The Aprefos 150mg Injection contains Aprepitant in two different doses. It belongs to a class of medicines called NK1 Receptor antagonists. It is used in combination with other medicines to prevent nausea and vomiting caused by chemotherapy (cancer treatment) in adults and children twelve years and older. Do not take this medicine if you are allergic to this medicine or any of its other ingredients.
Before taking the Aprefos 150mg Injection, it is important to inform your physician about all the medications you have been taking recently, including supplements and herbal medicines. Notify your doctor if you are planning a pregnancy or think you might be pregnant because this medicine is unsafe to use in such conditions.
This medication may reduce the efficacy of hormonal contraceptives. Talk with your doctor about alternative birth control options. Before taking this capsule, inform your doctor if you have liver disorders because the liver is crucial in breaking down medicine.
The doctor may, therefore, have to monitor the condition of the liver. Notify your doctor if you have had any allergic conditions or other diseases. Indigestion, tiredness, headache, hiccups, and loss of appetite are the common side effects of the Aprefos 150mg Injection.
Talk to your doctor if you have an intolerance to some sugars, as this medication contains sucrose. Do not give this medicine to children under 12 years of age because the medication has not been studied in this population.
Uses of Aprefos 150mg Injection
The Aprefos 150mg Injection is used in the treatment of the following:
- Prevents nausea and vomiting due to chemotherapy
Therapeutic Effects of Aprefos 150mg Injection
The Aprefos 150mg Injection blocks the action of a natural substance called neurokinin in the brain that causes nausea and vomiting. This medicine reduces the severity of chemotherapy-induced nausea and vomiting.
Interaction of Aprefos 150mg Injection with other drugs
Inform your healthcare provider about all your medicines, including prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products. Certain medications, such as Pimpzide, Terfenadine, and Cisapride, may interact with the Aprefos 150mg Injection and reduce effectiveness by causing undesirable side effects.
More Information about Aprefos 150mg Injection
- Store at room temperature 20°C to 25°C.
- Keep out of sight and reach of children.
- Store in the original package in order to protect it from moisture.
How to consume Aprefos 150mg Injection
Swallow the Aprefos 150mg Injection as a whole with water. Do not crush or chew the capsules. These capsules can be taken with or without food. Do not take more than recommended. If this medicine is prescribed, your physician will choose the dosage based on your medical condition because it differs for each person.
Safety Advices for Aprefos 150mg Injection
Pregnancy
This medication is unsafe because it may harm your unborn baby. Inform your physician if you are pregnant or planning to get pregnant before taking the Aprefos 150mg Injection. It will be given to you if clearly needed.
Breast Feeding
It is unknown whether the Aprefos 150mg Injection is excreted in human milk. So, it is not recommended to breastfeed while taking this capsule. Inform your physician before taking this medicine.
Lungs
Inform your doctor if you have or have had any lung condition before starting to take the Aprefos 150mg Injection. Contact your physician immediately if you experience any lung-related symptoms, such as difficulty breathing.
Liver
Inform your physician if you have any liver disorders before taking the Aprefos 150mg Injection, as this medication should be used with caution in liver disorder patients.
Alcohol
It is unknown whether consuming alcohol with an Aprefos 150mg Injection is. Consult your doctor for more information.
Driving
The medicine may make you dizzy. Avoid driving or handling heavy machines if you are unwell.
Side Effects of Aprefos 150mg Injection
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.
Serious side effects of the Aprefos 150mg Injection are:
- Allergic reactions (rash, itching, difficulty breathing, or swallowing)
Common side effects of the Aprefos 150mg Injection are:
- Tiredness
- Increased liver enzyme
- Indigestion
- Constipation
- Loss of appetite
- Hiccups
- Headache
Word of Advice
Report to your doctor if you are intolerant to any type of sugar because the Aprefos 150mg Injection contains sucrose. It is not advised for the patient under the age of 12. Notify your doctor if you are pregnant or planning to get pregnant or if you are breastfeeding. It is not recommended to consume this medicine if you have any underlying liver conditions. Your doctor may monitor your liver to understand its functioning level.
FAQs
Q 1. Can the Aprefos 150mg Injection be taken with other medications?
Aprefos 150mg Injection can be taken with other antiemetic drugs to provide more comprehensive prevention of chemotherapy-induced nausea and vomiting.
Q 2. Can the Aprefos 150mg Injection be used to treat other conditions?
Aprefos 150mg Injection is primarily used to prevent nausea and vomiting caused by chemotherapy or surgery, but it may also be used to treat other conditions, such as migraine headaches.
Q 3. Why patients with liver conditions should not consume an Aprefos 150mg Injection?
Because the Aprefos 150mg Injection initially gets metabolized in the liver. Hence, patients with liver disorders will find it difficult to metabolize this medicine, which may lead to an increased risk of side effects.
Q 4. What should I inform my doctor about before starting with the Aprefos 150mg Injection?
You need to inform your doctor if you have any underlying liver conditions, are allergic to the Aprefos 150mg Injection, or are intolerant to sucrose or any other sugar.
Q 5. Is the Aprefos 150mg Injection safe for use during pregnancy?
Aprefos 150mg Injection should only be used during pregnancy if the potential benefits outweigh the potential risks to the fetus.
Fact Box of Aprefos 150mg Injection
Molecule name: Aprepitant
| Therapeutic class: Antiemetic |
| Pharmacological class: NK1 Receptor antagonists | Indication: Prevents nausea and vomiting due to chemotherapy |
References
1. KD Tripathi, Essentials of Medical Pharmacology, Antiemetic, Prokinetic and Digestant Drugs, 7th edition, 2013, 669-670.
2. Goodman & Gilman’s, The Pharmacological Basics of Therapeutics, Treatment of disorders of bowel motility and water flux, 12th edition, 2011, 1345.
3. Ethypharm, Electronic Medicines Compendium (EMC), [Revised on Oct 2022]; [Accessed on 19th April 2023], https://www.medicines.org.uk/emc/files/pil.14650.pdf
4. Merck Sharp & Dohme Corp, US Food and Drug Administration, [Revised date April 2015], [Accessed on 19th April 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/021549s025lbl.pdf
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