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  3. Aptosyn 125mg/80mg Capsule

Substitutes

Aprecap 125mg/80mg Capsule

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Quick summary
Quick Summary

Aptosyn 125mg/80mg Capsule

Prescription Required
aprepitant
Written By:Aswini Priya VelmuruganPG in Biotechnology Reviewed By:Dr. Tejashwin AdigaMBBS

Last updated on 31 Mar 2026 | 09:30 AM (IST)

₹429

MRP: ₹1368.75

(You Save ₹939.75)

3 CAPSULE(s) IN A STRIP

69% OFF
Aptosyn 125mg/80mg Capsule
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Aptosyn 125mg/80mg Capsule

Prescription Required
Required

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APREPITANT

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VHB LIFE SCIENCES INC

69% OFF

Aptosyn 125mg/80mg Capsule
Preview
We are Rated 4.8 ⭐️ On Google

₹429

MRP: ₹1,368.75

Inclusive of all taxes

69% Off

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3 Capsule(s) In A Strip

3 Capsule(s) In A Strip

₹ 143.0/Unit

3 CAPSULE(s) IN A STRIP

Prescription Required
Prescription Required

Salt Composition

APREPITANT

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VHB LIFE SCIENCES INC

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Substitutes

Aprecap 125mg/80mg Capsule

GLENMARK PHARMA...

₹ 103.33/capsule

27% cheaper

Aprineon 125mg/80mg Capsule

NEON LABORATORI...

₹ 104.67/capsule

26% cheaper

Aprico Kit

PHARMACO INDUST...

₹ 119.00/capsule

16% cheaper

Aprebion Kit Capsule

SYMBION LIFE SC...

₹ 155.00/capsule

9% costlier

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Introduction

Aptosyn 125mg/80mg capsule contains the active constituent Aprepitant in two different doses. It belongs to a class of medicines called NK1 Receptor antagonists. It is used with a combination of other medicine to prevent nausea and vomiting caused by chemotherapy (cancer treatment) in adults and children of twelve years and older. Do not take this medicine if you are allergic to this medicine or any of the other ingredients of this medicine. 

Before taking Aptosyn 125mg/80mg capsule, it is important to inform your physician about all the medications you are taking recently, including supplements and herbal medicines. Notify your doctor if you planning a pregnancy or think you might be pregnant because this medicine is unsafe to use in such conditions. This medication may reduce the efficacy of hormonal contraceptives. Talk with your doctor about alternative birth control options. Before taking this capsule, inform your doctor if you have liver disorders because the liver is crucial in breaking down medicine.  

The doctor may therefore have to monitor the condition of the liver. Notify your doctor if you have had any allergic conditions or other diseases. Indigestion, tiredness, headache, hiccups, and loss of appetite are the common side effects of Aptosyn 125mg/80mg medication. Talk to your doctor if you have an intolerance to some sugars as this medication contains sucrose. Do not give this medicine to children under 12 years of age, because the medicines have not been studied in this population. Aptosyn 125mg/80mg price is based on the seller and Place. Aptosyn substitutes in India include other brands containing clarithromycin 125 mg and ambroxol 80 mg, such as Clariwin-A, Claribid-A, and Claribro-A.

Uses

Aptosyn 125mg/80mg uses are:

  • Prevents nausea and vomiting due to chemotherapy.

How Aptosyn 125mg/80mg Capsule Works

Aptosyn 125mg/80mg capsule blocks the action of a natural substance called neurokinin in the brain that causes nausea and vomiting. This medicine reduces the severity of chemotherapy-induced nausea and vomiting.

Interaction of Aptosyn 125mg/80mg Capsule with other drugs

Inform your healthcare provider about all your medicines, including prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products. Certain medications, such as Pimpzide, Terfenadine, and Cisapride may interact with Aptosyn 125mg/80mg and reduce effectiveness by causing undesirable side effects.

Storage Conditions

  • Store at room temperature 20°C to 25°C.
  • Keep out of sight and reach of children.
  • Store in the original package in order to protect it from moisture.

How to Use Aptosyn 125mg/80mg Capsule

Swallow the Aptosyn 125mg/80mg capsule as a whole with water. Do not crush or chew the capsules. These capsules can be taken with or without food. Do not take more than recommended. If this medicine is prescribed, your physician will choose the Aptosyn dosage based on your medical condition because it differs for each person.

Safety Advice for Aptosyn 125mg/80mg Capsule

Breast Feeding-Consult your doctor

Breast Feeding

Consult Your Doctor

It is unknown whether Aptosyn 125mg/80mg is excreted in human milk. So, it is not recommended to breastfeed while taking this capsule. Inform your physician before taking this medicine.

Alcohol-Consult your doctor

Alcohol

Consult Your Doctor

It is unknown whether consuming alcohol with Aptosyn 125mg/80mg. Consult your doctor for more information. 

Liver-Consult your doctor

Liver

Consult Your Doctor

Inform your physician if you have any liver disorders before taking the Aptosyn 125mg/80mg capsule, as this medication should be used with caution in liver disorder patients. 

Lungs-Consult your doctor

Lungs

Consult Your Doctor

Inform your doctor, if you have or had any lung condition before starting to take Aptosyn 125mg/80mg. Contact your physician immediately if you experience any lung-related symptoms such as difficulty to breath. 

Driving-unsafe

Driving

Unsafe

The medicine may make you dizzy. Avoid driving or handling heavy machines if you are unwell.

Pregnancy-unsafe

Pregnancy

Unsafe

This medication is unsafe because it may harm your unborn baby. Inform your physician if you are pregnant or planning to get pregnant before taking the Aptosyn 125mg/80mg capsule. It will be given to you if clearly needed.

Side Effects

Aptosyn capsule side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.

Serious

  • Allergic reactions (rash, itching, difficulty breathing, or swallowing)

Common

  • Tiredness
  • Increased liver enzyme
  • Indigestion
  • Constipation
  • Loss of appetite
  • Hiccups
  • Headache

Expert tips

  • Report to your doctor if you are intolerant to any type of sugar, as Aptosyn 125mg/80mg contains sucrose.

  • This medicine is not advised for patients under the age of 12.

  • Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.

  • Avoid using this medicine if you have underlying liver conditions.

  • Your doctor may monitor your liver function during treatment.

FAQs about Aptosyn 125mg/80mg Capsule

Q1.

Can Aptosyn 125mg/80mg be taken with other medications? 

Aptosyn 125mg/80mg can be taken with other antiemetic drugs to provide more comprehensive prevention of chemotherapy-induced nausea and vomiting. 

Q2.

Can Aptosyn 125mg/80mg be used to treat other conditions? 

Aptosyn for nausea and vomiting caused by chemotherapy or surgery, but it may also be used to treat other conditions, such as migraine headaches. 

Q3.

Why patients with liver conditions should not consume Aptosyn 125mg/80mg? 

Because the Aptosyn 125mg/80mg initially gets metabolized in the liver. Hence patients with liver disorders will feel difficult to metabolize this medicine which may lead to an increased risk of side effects. 

Q4.

What should I inform my doctor about before starting with Aptosyn 125mg/80mg? 

You need to inform if you have any underlying liver conditions if you are allergic to Aptosyn 125mg/80mg, and if you are intolerant to sucrose or any other sugar.  

Q5.

Is Aptosyn 125mg/80mg safe for use during pregnancy? 

Aptosyn 125mg/80mg should only be used during pregnancy if the potential benefits outweigh the potential risks to the fetus.

Fact Box

Molecule name: 

 Aprepitant 

Therapeutic class: 

Antiemetic

Pharmacological class:

NK1 Receptor antagonists

Indication:

Prevents nausea and vomiting due to chemotherapy 

References

  1. KD Tripathi, Essentials of Medical Pharmacology, Antiemetic, Prokinetic and Digestant Drugs, 7th edition, 2013, 669-670.
  2. Goodman & Gilman’s, The Pharmacological Basics of Therapeutics, Treatment of disorders of bowel motility and water flux, 12th edition, 2011, 1345.
  3. Ethypharm, Electronic Medicines Compendium (EMC), [Revised on Oct 2022]; [Accessed on 19th April 2023], https://www.medicines.org.uk/emc/files/pil.14650.pdf
  4. Merck Sharp & Dohme Corp, US Food and Drug Administration, [Revised date April 2015], [Accessed on 19th April 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/021549s025lbl.pdf

Disclaimer

MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.

Did you find this information helpful?

Author Details
Aswini Priya Velmurugan

Written By

Aswini Priya Velmurugan

PG in Biotechnology

Dr. Tejashwin Adiga

Reviewed By

Dr. Tejashwin Adiga

MBBS

Last updated : 31 Mar 2026 | 09:30 AM (IST)

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