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Asklerol 3% Injection
Salt Composition : Polidocanol
Manufacturer : SAMARTH LIFE SCIENCES PVT LTD
Origin of Medicine : India
1 Ampoule(s) Of 2ml
Introduction to Asklerol 3% Injection
Asklerol 3% injection contains an active ingredient called Polidocanol, which belongs to the group of medicines called sclerosing agents. It is used to treat varicose veins. It treats uncomplicated spider veins (varicose veins ≤1 mm in diameter) and uncomplicated reticular veins (varicose veins 1 to 3 mm in diameter) in the lower extremity. However, its effectiveness has not been studied in larger varicose veins that are greater than 3 mm in diameter. Varicose veins are swollen, pigmented, and twisted veins commonly found in the legs. They occur when blood flow is disrupted, causing blood to accumulate and resulting in the unsightly appearance of the legs. This injection helps reduce the appearance of varicose veins and improve blood flow.
Do not use Asklerol 3% injection if you are allergic to Polidocanol or any of its ingredients. Do not use this injection if you have uncontrolled systemic diseases like diabetes, hyperthyroidism, tuberculosis, asthma, neoplasm, systemic infections, blood dyscrasias, acute respiratory or skin diseases. Also, this injection should be avoided if you are immobile or have severe arterial occlusive disease (Fontaine stages III and IV). Thromboembolic diseases and high risk of thrombosis (such as hereditary thrombophilia, use of hormonal contraceptives, hormone replacement therapy, obesity, smoking, and extended periods of immobility) are also contraindications. Microfoam sclerotherapy is not recommended if you have a known symptomatic right-to-left shunt (e.g., symptomatic patent foramen ovale).
Before starting the treatment, inform your doctor if you have certain conditions like asymptomatic but known PFO, visual or neurological symptoms after previous microfoam treatment, fever, bronchial asthma or allergies, arterial occlusive disease, leg edema, inflammatory skin disease, symptomatic microangiopathy or neuropathy, and those using anticoagulation medication. Before starting the treatment, inform your doctor if you have any allergies or a history of anaphylaxis. Be prepared to treat anaphylaxis in case of an allergic reaction during the procedure. Also, discuss with your doctor the risks associated with venous thrombosis, pulmonary embolism, and arterial embolism. Do not inject the medication intra-arterially to avoid tissue ischemia and necrosis. Notify your doctor if you are pregnant, planning to get pregnant, or think you may be pregnant or are breastfeeding. Asklerol 3% injection contains 5% (v/v) ethanol, which may harm individuals with alcoholism or undergoing alcoholism treatment with Disulfiram.
Uses of Asklerol 3% Injection
- Treats uncomplicated spider veins.
- Treats uncomplicated reticular veins
Therapeutic Effects of Asklerol 3% Injection
Asklerol 3% injection works by causing irritation and inflammation in the treated blood vessels, leading to the formation of blood clots and the closure of the veins. This process helps improve the appearance of varicose and spider veins and redirects blood flow to healthier vessels.
Interaction of Asklerol 3% Injection with other drugs
Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications may interact with Asklerol 3% injection and can cause undesirable side effects.
More Information about Asklerol 3% Injection
- Keep out of sight and reach of pets and children.
- Do not store above 25°C.
- Do not freeze the medicine.
- Always check the expiry date before using it.
How to consume Asklerol 3% Injection
Asklerol 3% injection will be injected intravenous (vein) to you by a healthcare professional in a hospital setting. Do not self-administer. Your doctor will decide the dose, route of administration, and frequency based on your disease condition and other factors.
Safety Advices for Asklerol 3% Injection
It is unknown whether Asklerol 3% injection is harmful to the unborn baby. Before starting the treatment, inform your doctor if you are pregnant, planning to get pregnant, or think you may be pregnant.
It is unknown whether Asklerol 3% injection is excreted in breast milk. So, before starting the treatment, inform your doctor if you are breastfeeding. Contact your doctor for more information
It is unknown whether Asklerol 3% injection is safe for patients with lung problems. Inform your physician if you have any lung disease before starting the treatment. Contact your doctor if you experience any lung-related symptoms.
Limited information is available on the use of Asklerol 3% injection in patients with liver disease. Therefore, it is crucial to consult your doctor before considering its usage to ensure it is safe and appropriate for your condition.
It is unsafe to consume alcohol while taking Asklerol 3% injection. Before start taking the treatment inform you doctor if you are undergoing alcoholism treatment.
It is unknown whether Asklerol 3% injection alters driving ability. However, if you experience side effects like tiredness or drowsiness, avoid driving and using machines.
Side Effects of Asklerol 3% Injection
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.
- Cell injury
- Cardiac arrest
- Blockage in lung arteries
- Cardiac dysfunction due to intense stress
- Short term injection site pain
- Temporary skin discoloration after treatment
- Injection site blood clots
Word of Advice
An emergency kit should be available in case of an anaphylactic reaction. Prior to treatment, the healthcare professional should assess the patient's risk factors and inform them about the associated risks. Post-treatment follow-up is essential to monitor for deep vein thrombosis development.
Follow your doctor's recommendations closely throughout the process. If you experience any concerning symptoms or side effects, be sure to inform your healthcare provider immediately. Do not stop the medicine until your doctor advises. Your medical professional will inform you if you need any dose adjustments. Contact your doctor for more information.
Q 1. Can I use Asklerol 3% injection if I’m pregnant?
Consult your medical professional regarding the use of Asklerol 3% injection during pregnancy because it is unknown. The potential benefits and risks should be carefully assessed. Your doctor will suggest taking this medicine only if it's necessary
Q 2. What is Asklerol 3% injection?
Asklerol 3% injection belongs to the group of medicines called sclerosing agents. It is used to treat varicose veins. It treats uncomplicated spider veins (varicose veins ≤1 mm in diameter) and uncomplicated reticular veins (varicose veins 1 to 3 mm in diameter) in the lower extremity. However, its effectiveness has not been studied in larger varicose veins that are greater than 3 mm in diameter.
Q 3. Can I use Asklerol 3% injection with other medications?
Before using Asklerol 3% injection, it is essential to consult your doctor, as they can interact with various other medications. Talking to your doctor will help ensure the safe and appropriate use of this medicine with your current medication regimen.
Q 4. What should I do if I have a reaction to Asklerol 3% injection?
If you experience any side effects from a Asklerol 3% injection, such as skin irritation, redness, or blistering, stop using the medicine and contact your doctor immediately.
Q 5. What are the side effects of Asklerol 3% injection?
The common side effect of Asklerol 3% injection are short term injection site pain, temporary skin discoloration after treatment and injection site blood clots. Contact your doctor immediately if you experience any side effect.
Fact Box of Asklerol 3% Injection
|Molecule Name: Polidocanol
|Therapeutic class: Antiplatelet Agents
|Pharmacological class: Monoclonal anti-glycoprotein IIb/IIIa receptor antibody
1. Prevents blood clots during Percutaneous coronary intervention.
2. Unstable angina.
- Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Blood coagulation and anticoagulant, fibrinolytic, and antiplatelet drugs, 12th edition, 2011, 870.
- KD Tripathi, Essentials of Medical Pharmacology, Drugs affecting Coagulation, bleeding and thrombosis, 7th edition, 2013, 631.
- Janssen Biotech, Inc; US Food and Drug Administration; [Revised on August 2019] [ Accessed on 2nd August 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/103575s5318lbl.pdf
- Centocor B.V; US Food and Drug Administration [Revised on 4th November 1997] [ Accessed on 2nd August 2023] abcicen110597-lab.pdf (fda.gov)
- Drugs.com,Polidocanol, [Revised on 10th April 2023] [ Accessed on 2nd August 2023] Polidocanol: Indications, Side Effects, Warnings - Drugs.com
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