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Astronin Nasal Spray
Salt Composition : Calcitonin
Manufacturer : MASTRO BILOGICALS
Origin of Medicine : India
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Introduction to Astronin Nasal Spray
Astronin nasal spray contains an active component as Calcitonin. It is a hormone that plays a role in calcium regulation in the body. The thyroid gland primarily produces it and helps to lower blood calcium levels by inhibiting calcium release from bones and increasing calcium excretion by the kidneys. In medical practice, synthetic versions are used as medications to treat certain conditions. This medication treats postmenopausal osteoporosis, Paget's disease (type of bone disease), and hypercalcemia and prevents bone loss in patients suffering from fractures. It makes the bone stronger and prevents further damage. Astronin nasal spray may alleviate bone pain in some cancer patients whose cancer has metastasized to the bones.
This medication should not be used in individuals who have a known hypersensitivity or allergy to Astronin nasal spray or any of its components. Allergic reactions may include skin rash, itching, swelling, or difficulty breathing. This medication is used to lower blood calcium levels, so it should not be administered to patients with already low calcium levels (hypocalcemia). Patients with impaired kidney function may need dosage adjustments, as the kidneys excrete this medication. Close monitoring is essential to prevent any potential accumulation of the medication. Astronin nasal spray may cause gastrointestinal side effects such as nausea, vomiting, or diarrhea.
Uses of Astronin Nasal Spray
Astronin nasal spray is used to treat the following:
- Paget’s disease
- Postmenopausal osteoporosis
- Prevention of fracture.
Therapeutic Effects of Astronin Nasal Spray
The therapeutic effect of Astronin nasal spray lies in its ability to regulate calcium levels in the body. As a hormone medication, this medication helps to reduce bone resorption and inhibits the release of calcium from bones, leading to decreased blood calcium levels. This effect is particularly beneficial in treating conditions such as osteoporosis, where it can slow down bone loss and potentially reduce the risk of fractures. This medicine also finds application in managing Paget's disease of bone, where it helps control abnormal bone remodeling and alleviates associated symptoms. Moreover, in emergency cases of hypercalcemia, this medication rapidly lowers blood calcium levels, relieving severe symptoms and preventing complications.
Interaction of Astronin Nasal Spray with other drugs
Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Astronin nasal spray, reducing effectiveness by causing undesirable side effects.
More Information about Astronin Nasal Spray
- Store at room temperature, between 20°C to 25°C (68°F to 77°F).
- Keep away from moisture, heat, and light.
- It should not be frozen.
- Keep away from children and pets.
How to consume Astronin Nasal Spray
The usage of Astronin nasal spray medication depends on its formulation, which can be injectable, nasal spray, or oral form (tablet). When using the injectable form, it is usually administered subcutaneously or intramuscularly. The nasal spray is administered into one nostril, alternating nostrils daily, and it's essential to follow the specific instructions provided with the product. For oral use, this medication is used in tablet form; it is typically taken with water on an empty stomach or as directed by the healthcare provider. The dosage and frequency of administration vary depending on the medical condition being treated, and it is crucial to adhere to the prescribed regimen.
Safety Advices for Astronin Nasal Spray
The safety of Astronin nasal spray use during pregnancy has not been extensively studied, and its use in pregnant individuals should generally be avoided, and healthcare provider consultation is required.
The safety of using Astronin nasal spray during breastfeeding has not been well-established, and it is generally recommended to avoid its use while breastfeeding.
Patients with lung infections or other respiratory conditions should consult their healthcare providers to ensure the appropriate use of Astronin nasal spray or any other medication.
Astronin nasal spray is primarily metabolized in the liver; caution is advised when administering this medication to patients with liver dysfunction.
There is no direct interaction between Astronin nasal spray and alcohol. However, it's always advisable to avoid excessive alcohol consumption while on any medication, as alcohol can interfere with the body's ability to metabolize drugs, potentially leading to increased side effects or reduced medication efficacy.
Astronin nasal spray is not known to cause drowsiness or impair cognitive functions that could significantly affect driving ability. If you experience dizziness, lightheadedness, or any other side effects that could affect your ability to drive safely, refrain from driving or operating heavy machinery until you feel comfortable.
Side Effects of Astronin Nasal Spray
Astronin nasal spray causes some side effects like all medications, although not everyone will experience them.
- Allergic reactions
- Hypocalcemia (lower blood calcium levels)
- Respiratory issues
- Gastrointestinal bleeding
- Flushing of the face or skin
- Injection site reactions (for injectable formulations)
Word of Advice
Patients with a history of hypersensitivity reactions to Astronin nasal spray or its components should avoid its use. Caution is necessary for individuals with existing hypocalcemia or conditions that may predispose them to low calcium levels, as this medication can further lower blood calcium levels. Liver impairment may require dosage adjustments, and patients with certain malignancies should be carefully evaluated before using it. Its safety during pregnancy and breastfeeding has not been extensively studied, so caution is advised. Long-term use may be associated with developing tumor-induced osteomalacia and osteosarcoma (type of bone cancer) in rare cases. Regular monitoring and follow-up with healthcare providers are essential to ensure safe and effective use of this medication.
Q 1. What are the common side effects of Astronin nasal spray?
Common side effects of Astronin nasal spray may include nausea, vomiting, diarrhea, headache, flushing of the face or skin, injection site reactions (for injectable formulations), and nasal irritation or dryness (for nasal spray).
Q 2. How long should Astronin nasal spray be used?
The duration of Astronin nasal spray use depends on the specific medical condition being treated and the healthcare provider's recommendation. In some cases, it is intended for short-term use only. Long-term use, especially for osteoporosis, may not be recommended due to concerns about its overall effectiveness and safety.
Q 3. Can Astronin nasal spray be used in children and the elderly?
The safety and effectiveness of Astronin nasal spray in pediatric patients have not been well-established, and healthcare providers should carefully consider its use in children and adolescents. Elderly patients may be more susceptible to side effects, especially gastrointestinal disturbances, and dose adjustments may be necessary.
Q 4. Can Astronin nasal spray be used for chronic pain management?
While Astronin nasal spray has been used to manage bone pain in some cancer patients, its role in chronic pain management is limited, and other treatments may be more effective and preferred.
Q 5. What should I do if I miss a dose of Astronin nasal spray?
If you miss a dose of Astronin nasal spray, follow the specific dosing instructions provided by your healthcare provider or the medication's packaging. Do not double the dose to catch up. If you are unsure about what to do, contact your healthcare provider or pharmacist for guidance.
Q 6. Does Astronin nasal spray have an impact on thyroid function?
Astronin nasal spray may transiently increase serum thyroglobulin levels, leading to temporary effects on thyroid function tests. If you are undergoing thyroid function testing, inform your healthcare provider that you are taking this medication to avoid misinterpreting test results.
Fact Box of Astronin Nasal Spray
Molecule name: Calcitonin
Therapeutic class: Bone Metabolism Regulators
Pharmacological class: Calcitonin
2. Paget’s disease
3. Postmenopausal osteoporosis
4. Prevention of fracture
- Novartis Pharmaceuticals Corporation, FDA (Food and Drug Safety Administartion) [Revised on 2011] [Accessed on 21st July 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/017808s034lbl.pdf
- Essential Pharma (M) Limited, Health Products Regulatory Authority, [Revised on Sep 2020] [Accessed on 21st July 2023], https://www.hpra.ie/img/uploaded/swedocuments/Licence_PA22644-004-001_13112020161254.pdf
- K D Tripathi, Hormones and Drugs affecting calcium balance, Essentials of Medical Pharmacology, 8th Edition, 2019, 360-372.
- Thomas D. Nolin and Peter A. Friedman, Agents Affecting Mineral Ion Homeostasis and Bone Turnover, Goodman & Gilman’s The Pharmacological Basis of Therapeutics, 13th Edition, 2018, 887-906.
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