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Bernitrim Injection 5ml

Prescription Required

Salt Composition : Cotrimoxazole


Origin of Medicine : India

MRP: 239
Price :136
You Save :103 (43%)

1 Ampoule(s) Of 5ml

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Introduction to Bernitrim Injection 5ml

Bernitrim injection contains an active component such as Cotrimoxazole. It is a medication that combines two active ingredients as trimethoprim and sulfamethoxazole. This medication is commonly used to treat uncomplicated UTIs caused by susceptible bacteria. It can be prescribed for certain types of respiratory tract infections, such as bronchitis and certain types of pneumonia. This medication might be used to treat gastrointestinal infections caused by susceptible bacteria. It can be effective in treating certain bacterial skin infections and wounds. It might be prescribed to prevent or treat traveler's diarrhea in certain situations. It is also used as a preventive measure against PCP, a type of pneumonia affecting individuals with weakened immune systems, such as HIV/AIDS.

Individuals who have a known hypersensitivity or allergy to Bernitrim injection or any of its components should not take this medication. Serious allergic reactions can occur in such cases. Individuals with a deficiency of folic acid (folate) should avoid using it. Individuals with severe liver or kidney dysfunction may be unable to process the medication, leading to potential adverse effects effectively. It can affect blood cells, potentially leading to blood disorders like anemia, thrombocytopenia, or agranulocytosis. Individuals with pre-existing blood disorders or conditions that affect blood cell production should use Bernitrim injection cautiously. It can be used in children for certain bacterial infections, but dosage is based on weight and age. It can be used in older adults, but caution is needed due to potential age-related changes in kidney function and other health conditions. 

Uses of Bernitrim Injection 5ml

Bernitrim injection is used in the following:

  • Urinary tract infections (UTIs)
  • Respiratory tract infections
  • Gastrointestinal infections
  • Skin and soft tissue infections
  • Traveler's diarrhea
  • Pneumocystis jirovecii pneumonia (PCP) prevention
  • Toxoplasmosis
  • Nocardiosis
  • Other bacterial infections

Therapeutic Effects of Bernitrim Injection 5ml

Bernitrim injection involves a synergistic inhibition of bacterial folate synthesis. It combines trimethoprim, which blocks a specific enzyme in the pathway, with sulfamethoxazole, which competes with para-aminobenzoic acid, a folate precursor. This dual action disrupts the bacteria's ability to synthesize DNA, RNA, and proteins, inhibiting their growth and effectively treating infections.

Interaction of Bernitrim Injection 5ml with other drugs

Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Bernitrim injection, reducing effectiveness by causing undesirable side effects. 

More Information about Bernitrim Injection 5ml

  • Store at room temperature, between  20°C and 25°C
  • Keep away from moisture, heat, and light.
  • It should not be frozen.
  • Keep away from children and pets.

How to consume Bernitrim Injection 5ml

Bernitrim injection can be administered as an intravenous injection. The intravenous route delivers the medication directly into the bloodstream. The administration route choice depends on the infection's severity and the patient's condition.

Safety Advices for Bernitrim Injection 5ml

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Bernitrim injection is unsafe during pregnancy due to potential risks to the developing fetus. 

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Breast Feeding


Due to the potential transfer of Bernitrim injection into breast milk, using this medication during breastfeeding is unsafe.

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Bernitrim injection might be used for certain respiratory infections, but its use depends on the specific infection and susceptibility of bacteria causing it. Always consult a doctor before taking this medication.

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Bernitrim injection should be used cautiously in individuals with liver impairment. Dosage adjustments might be necessary. Consult a healthcare provider.

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Alcohol can interact with Bernitrim injection and increase the risk of side effects. It's generally not safe to take alcohol during treatment.

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Bernitrim injection might cause dizziness or drowsiness in some individuals.It is not safe to drive while on this medication.

Side Effects of Bernitrim Injection 5ml

Bernitrim injection causes some side effects like all medications, although not everyone will experience them. 


  • Severe allergic reactions
  • Blood disorders
  • Liver and kidney problems
  • Stevens-johnson syndrome (SJS)
  • Toxic epidermal necrolysis (TEN)
  • Serious gastrointestinal effects
  • Respiratory effects
  • Hyperkalemia
  • Central nervous system effects
  • Serum sickness-like reaction


  • Nausea
  • Vomiting
  • Diarrhea
  • Mild allergic reactions (skin rash)

Word of Advice

Inform your healthcare provider about allergies, medical history (including kidney and liver problems), and medications you are taking before using Bernitrim injection. Discuss potential risks if pregnant, breastfeeding, or planning pregnancy. Monitor kidney and liver function regularly. Watch for severe allergic reactions, blood disorders, and serious skin reactions. Stay hydrated and be cautious in sunlight. Follow prescribed dosages and avoid changing medications without consulting a healthcare provider. While traveling, plan for medication supply. Store properly, dispose of unused medication, and immediately address emergencies. Maintain communication with your healthcare provider and report any new symptoms. 


Q 1. What should I do if I miss a dose of Bernitrim injection?

If you miss a dose of Bernitrim injection, take it as soon as you remember. If it's close to the time for the next dose, skip the missed dose and resume your regular dosing schedule.

Q 2. Can I stop taking Bernitrim injection once I start feeling better?

No, completing the full course of Bernitrim injection as your healthcare provider prescribes is important. Stopping early could lead to incomplete treatment and the risk of the infection returning or developing antibiotic resistance.

Q 3. Can Bernitrim injection affect birth control efficacy?

Bernitrim injection might interfere with the effectiveness of hormonal birth control methods like birth control pills. Consider using additional contraception methods while on Bernitrim injection.

Q 4. Can Bernitrim injection be used for viral infections like the common cold?

No, Bernitrim injection is an antibiotic effective against bacterial infections. It is not effective against viral infections like the common cold or flu.

Q 5. Can I share my Bernitrim injection prescription with someone else who has similar symptoms?

No, Bernitrim injection is prescribed based on individual medical assessments. Sharing medication can lead to inappropriate treatment and potential risks.

Q 6. Should I discontinue the Bernitrim injection if I experience mild side effects?

It's important to consult your healthcare provider before discontinuing any medication. Some mild side effects might improve but always follow medical advice.

Fact Box of Bernitrim Injection 5ml

Molecule name: Cotrimoxazole

Therapeutic class:  Antibiotics

Pharmacological class: Antimicrobial agents


1. Urinary tract infections (UTIs)

2. Respiratory tract infections

3. Gastrointestinal infections

4. Skin and soft tissue infections

5.Traveler's diarrhea

6. Pneumocystis jirovecii pneumonia (PCP) prevention

7. Toxoplasmosis

8. Nocardiosis

9. Other bacterial infections


  1. KD Tripathi, Essentials of Medical Pharmacology, Sulfonamides, Cotrimoxazole, and Quinolones, 7th edition, 2013, 706-708.
  2. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Sulfonamides, Trimethoprim-Sulfamethoxazole, Quinolones, and Agents for urinary tract infections, 12th edition, 2011, 1468-1470.
  3. Aspen, Electronic medicines compendium (EMC), [ Revised on 12th Jun 2023] [ Accessed on August 31st, 2023],
  4. Sun Pharmaceutical Industries, Inc, US Food and Drug Administration, [ Revised on 3/2017] [ Accessed on 31st August 2023,


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