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Hematopoietic progenitor cell transplantation
Chronic myelogenous leukaemia
Polycythaemia vera (type of cancer that causes increase in red blood cells)
Thrombocythemia (increased number of platelets in the blood)
Myelofibrosis (type of blood cancer where scar tissues are formed in bone marrow)
Hemoglobinopathies (a genetic disorder that produces abnormal haemoglobin)

"}},{"id":"4057927b-af26-4a87-a01f-f2972295ee06","type":"PARA","position":3,"content_placement":1,"data":{"heading":"Therapeutic Effects of Bucelon 2mg Tablet","text":"

Bucelon works by interfering with the DNA replication process, which is necessary for the cells to divide. It stops tumor growth by inhibiting cell division. They cause cytotoxicity by reversibly binding to nucleophilic groups on different cell components. Alkylation of DNA is most likely the crucial cytotoxic reaction that kills tumor cells. It damages the DNA and RNA of the cancer cells by stopping their growth and multiplication. They are combined with other medications to treat various lymphatic and solid cancers.

"}},{"id":"d7045032-43c3-4ea4-a9cb-a24062779777","type":"PARA","position":4,"content_placement":1,"data":{"heading":"Interaction of Bucelon 2mg Tablet with other drugs","text":"

Inform your physician regarding any prescribed medicines, over-the-counter medications, nutritional or vitamin supplements, and herbal products that you are taking or have taken before the treatment. Certain medications may interact with Bucelon 2mg Tablet and can cause potential side effects.

"}},{"id":"77d77dd2-d72d-4483-a417-aa472f18f9af","type":"PARA","position":5,"content_placement":1,"data":{"heading":"More Information about Bucelon 2mg Tablet","text":"

Store it at room temperature and away from excess heat and moisture. Store at 15° to 25°C (59° to 77°F) in a dry place. Keep it out of sight and reach of children.

"}},{"id":"d9072db3-9d1a-4e64-b6bf-1bc2fdc96f71","type":"PARA","position":6,"content_placement":1,"data":{"heading":"How to consume Bucelon 2mg Tablet","text":"

Your physician will decide the dose and duration of this therapy. The dose of Busulfan depends on your blood cancer. Swallow the tablets with plenty of water. Do not break, crush or chew them. You can take busulfan tablets before or after meals. Don't stop the medication until or unless your doctor advises. If you missed the dose, do not take double the doses. Inform your physician about your missed dose.

"}},{"id":"826c2286-5fdf-4667-a260-dc61c7198f52","type":"SAFETY_ADVICE","position":7,"content_placement":2,"data":{"heading":"Safety Advice for Bucelon 2mg Tablet","safety_list":[{"id":"429594b4-281a-4cb4-aa60-20f2a7c74820","advice":"Breast Feeding","tag":"unsafe","description":"

If you are breastfeeding or plan to breastfeed your baby, talk to your physician because the drug may secrete in breast milk.

","imageUrl":"https://assets.mrmed.in/others/file-1674132409667-45039420-Breatfeeding.jpg"},{"id":"62647bb5-9b07-45b5-bb22-b6e923841890","advice":"Alcohol","tag":"Consult your doctor","description":"

It is not known whether it is safe to consume alcohol with Bucelon 2 Tablet. Please consult your doctor.

","imageUrl":"https://assets.mrmed.in/others/file-1674132415913-10337479-Alcohol.jpg"},{"id":"1fddc57f-741a-4a5b-80fb-0219ea3aa57d","advice":"Liver","tag":"Consult your doctor","description":"

Discuss with your physician before taking this medicine if you have liver problems.

","imageUrl":"https://assets.mrmed.in/others/file-1674132424807-417765861-Liver.jpg"},{"id":"bd561f8c-0625-4aa4-94f3-eb51311b4be0","advice":"Lungs","tag":"Consult your doctor","description":"

It is unknown whether Bucelon 2mg Tablet can be given to patients with lung diseases. Please inform your doctor if you have any lung problems.

","imageUrl":"https://assets.mrmed.in/others/file-1674132427859-226731771-Lungs.jpg"},{"id":"094a5ea6-6435-42a8-9312-4bd0ddf7676f","advice":"Driving","tag":"unsafe","description":"

It is not known whether Bucelon 2 Tablet alters the ability to drive. Do not drive if you experience symptoms affecting your ability to concentrate and react.

","imageUrl":"https://assets.mrmed.in/others/file-1674132431331-421990512-Driving.jpg"},{"id":"666248b4-e283-40e6-b74a-3f3674eafb23","advice":"Pregnancy","tag":"unsafe","description":"

Bucelon 2mg is unsafe during pregnancy. It may cause fetal harm when administered. If you are pregnant or planning to get pregnant, ask your doctor or pharmacist for advice before taking this medicine. This applies to men and women because the drug may harm your sperm or eggs.

","imageUrl":"https://assets.mrmed.in/others/file-1674132401469-949914510-Pregnancy.jpg"}]}},{"id":"f5c9df48-1187-44f6-9023-86cd71fd4698","type":"PARA","position":8,"content_placement":1,"data":{"heading":"Side Effects of Bucelon 2mg Tablet","text":"

Side effects are unwanted symptoms caused by medicines. Even though all medications cause side effects, not everyone gets them.

Severe

Myelosuppression (decreased bone marrow activity)

Common side effects

Thalassaemia
Hair loss
Patches of dark skin
Blood in urine
Decrease in the number of blood cells and platelets
Nausea and vomiting
Jaundice
Infertility and sterility
Pneumonia syndrome

"}},{"id":"1193619c-7548-46cd-8ee8-38a37013c48e","type":"PARA","position":9,"content_placement":1,"data":{"heading":"Word of Advice","text":"

Inform the doctor if the patient has taken radiotherapy priorly to the treatment. If you have other medical conditions like heart disease, lung, kidney, or liver problems. Tell your doctor if you have gout symptoms (pain and swollen joints caused by uric acid crystals).

"}},{"id":"d4c3f9e4-702e-49de-9324-387944aa6805","type":"FAQ","position":10,"content_placement":2,"data":{"heading":"FAQs about Bucelon 2mg Tablet","faq_list":[{"id":"71a22b6e-69db-4050-88f9-33916a2dde92","question":"

Can Bucelon 2 mg tablets cause infertility?

","answer":"

Yes, bucelon 2 mg tablets can cause infertility in both the men and women because it affects the sperm cells and egg. Consult the doctor before taking this medication.

"},{"id":"53cd3704-46d7-4478-8f44-fe30debd6c42","question":"

How can a Busulfan 2 mg tablet be taken?

","answer":"

Bucelon 2 mg tablet is taken orally. Swallow the whole tablet with water. If you have missed the dose, inform your physician. Don't take double the dose.

"},{"id":"e7f0aa47-4644-4d88-b5c8-c10abfb02275","question":"

Can bucelon 2 mg be used during pregnancy?

","answer":"

No, it is highly unsafe to use this medication during pregnancy as they can cause harmful effects on the developing fetus.

"},{"id":"8ad4d4c3-6a63-43d5-9125-9d61196c35a1","question":"

Are there any special precautions patients should be aware of before starting treatment?

","answer":"

Patients should inform the physician about the pregnancy, breastfeeding, or if planning for a family. Patients should also inform about past medical and medication history.

"},{"id":"6b7ac38a-e45a-46b9-a065-1615de9c2d8c","question":"

What is the package insert that comes with Bucelon 2 mg?

","answer":"

The package insert contains all the scientific information(indications, uses, side effects, safety, and warning, contraindications) about the drug.

"},{"id":"8c3a46fe-3e80-4210-a670-496b3d5093e1","question":"

Does bucelon 2mg cause permanent hair loss?

","answer":"

Yes, Bucelon 2 mg tablet chemotherapy causes hair loss. Consult the physician about excessive hair loss.

"},{"id":"957b01ce-0383-4028-ad9c-199a30791fd0","question":"

What does a bucelon 2 mg tablet look like?

","answer":"

It looks like a white, scored tablet packed in a bottle containing 25 tablets per bottle.

"}]}},{"id":"d464f35d-c932-4e9a-95b1-447d13cee095","type":"PARA","position":11,"content_placement":3,"data":{"heading":"Fact Box of Bucelon 2mg Tablet","text":"

Molecule Name: Busulfan

Therapeutic class: Anticancer

Pharmacological class: Alkylating agent - Alkyl sulfonates

Indication:

1. Chronic myelogenous leukemia

2. Hematopoietic progenitor cell transplantation

3. Polycythaemia vera

4. Thrombocythemia

5. Myelofibrosis

6. Hemoglobinopathies

7. Congenital metabolic diseases

"}},{"id":"58f1ab81-b5c8-4df5-b263-72fe0997f08d","type":"PARA","position":12,"content_placement":3,"data":{"heading":"References","text":"

Aspen, Electronic Medicines Compendium(EMC) (Revised on: July 2020) https://www.medicines.org.uk/emc/product/4653/pil#gref (Accessed: December 14, 2022).
Busulfan (Revised on: May 19, 2015) National Cancer Institute. https://www.cancer.gov/about-cancer/treatment/drugs/busulfan (Accessed: December 14, 2022).
Anton Wellstein, Giuseppe Giaccone, Michael B. Atkins, and Edward A. Sausville, Pharmacotherapy of Neoplastic disease: cytotoxic drugs, Goodman & Gilman’s Pharmacological Basis of Therapeutics, 13th Edition, 2018, 1167-1174.
Buggia I, Locatelli F, Regazzi MB, Zecca M. Busulfan. Ann Pharmacother. 1994 Sep;28(9):1055-62. doi: 10.1177/106002809402800911. PMID: 7803883.

"}},{"id":"7685a69c-9dcf-474a-a2c9-f60ed9cb5ca4","type":"DISCLAIMER","position":13,"content_placement":5,"data":{"heading":"Disclaimer","text":"

MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.

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