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Get Genuine Medicines At Your Doorstep. 📞 89391 69999","seo_keywords":""},"id":"60a728988d83db59164049bc"},"minorPush":null,"majorPush":null}],["$","span",null,{"aria-hidden":"true","className":"w-px h-px block","style":{"marginLeft":"0.25rem","marginTop":"1rem"}}]]}],["$","div",null,{"className":"!sticky top-[140px] hidden md:block","children":["$","$L21",null,{"content":[{"id":"973e815a-f4e2-4d8a-b95c-badf1c711364","type":"PARA","position":1,"content_placement":1,"data":{"heading":"Introduction to Bufatas IV 60mg Injection","text":"$22"}},{"id":"76511d68-21c3-4e2b-8999-b1340d379d5e","type":"PARA","position":2,"content_placement":1,"data":{"heading":"Uses of Bufatas IV 60mg Injection","text":"

Hematopoietic progenitor cell transplantation
Chronic myelogenous leukemia
Polycythaemia vera (a type of cancer that causes an increase in red blood cells)
Thrombocythemia (increased number of platelets in the blood)
Myelofibrosis (type of blood cancer where scar tissues are formed in bone marrow)
Hemoglobinopathies (a genetic disorder that produces abnormal hemoglobin)
Brain Malignancies

"}},{"id":"a3f4b80e-912a-4a48-94a9-3332c979941d","type":"PARA","position":3,"content_placement":1,"data":{"heading":"Therapeutic Effects of Bufatas IV 60mg Injection","text":"

Bufatas IV 60 mg injection works by interfering with the DNA replication process, which is necessary for the cells to divide. It stops tumor growth by inhibiting cell division. It causes cytotoxicity by reversibly binding to nucleophilic groups on different cell components. Alkylation of DNA is most likely the crucial cytotoxic reaction that kills tumor cells. It damages the DNA and RNA of the cancer cells by stopping their growth and multiplication. They are combined with other medications to treat various lymphatic and solid cancers.

"}},{"id":"1d131089-399d-4a3e-ae9a-209bbf55fc5e","type":"PARA","position":4,"content_placement":1,"data":{"heading":"Interaction of Bufatas IV 60mg Injection with other drugs","text":"

Inform your physician regarding any prescribed medicines, over-the-counter medications, nutritional or vitamin supplements, and herbal products that you are taking or have taken before the treatment. Certain medications may interact with Bufatas IV 60mg Injection and can cause potential side effects.

"}},{"id":"335ff384-91ba-463e-8c5c-adc8f6a9e126","type":"PARA","position":5,"content_placement":1,"data":{"heading":"More Information about Bufatas IV 60mg Injection","text":"

Unopened vials of Bufatas IV 60 mg injection should be stored under refrigerated conditions between 2°C to 8°C (36°F to 46°F). Unused medications should be disposed of properly. Keep it out of sight and reach of children.

"}},{"id":"4344ab3b-333e-423d-83f8-bfc2debcbdac","type":"PARA","position":6,"content_placement":1,"data":{"heading":"How to consume Bufatas IV 60mg Injection","text":"

Your physician will decide the formulation, dose, and duration of this therapy. The dose of Bufatas IV 60 mg injection depends on your blood cancer. If you are prescribed the injection, your healthcare professional will administer the injection. Do not self-administer. The injection is administered as an intravenous infusion into the vein. Don't stop the medication until or unless your doctor advises. If you missed the dose, do not take double the doses. Inform your physician about your missed dose.

"}},{"id":"809ba247-eb89-48e7-9d11-5a0a610acebf","type":"SAFETY_ADVICE","position":7,"content_placement":2,"data":{"heading":"Safety Advice for Bufatas IV 60mg Injection","safety_list":[{"id":"4a9fa4a7-d4a3-43e4-8d26-93dbcc4beb0e","advice":"Breast Feeding","tag":"unsafe","description":"

If you are breastfeeding or plan to breastfeed your baby, talk to your physician because the drug may secrete in breast milk.

","imageUrl":"https://assets.mrmed.in/others/file-1674132409667-45039420-Breatfeeding.jpg"},{"id":"e81fcdb6-6bda-4c2a-9a1c-ca3cc1508c39","advice":"Alcohol","tag":"Consult your doctor","description":"

It is not known whether it is safe to consume alcohol with Bufatas IV 60mg Injection. Please consult your doctor.

","imageUrl":"https://assets.mrmed.in/others/file-1674132415913-10337479-Alcohol.jpg"},{"id":"ff45c486-c6c1-4b55-b684-7ad05664a9fa","advice":"Liver","tag":"Consult your doctor","description":"

Discuss with your physician before taking this medicine if you have liver problems.

","imageUrl":"https://assets.mrmed.in/others/file-1674132424807-417765861-Liver.jpg"},{"id":"23a83376-f13c-482c-b665-399325ef03df","advice":"Lungs","tag":"Consult your doctor","description":"

It is unknown whether Bufatas IV 60mg Injection can be given to patients with lung diseases. Please inform your doctor if you have any lung problems.

","imageUrl":"https://assets.mrmed.in/others/file-1674132427859-226731771-Lungs.jpg"},{"id":"590107fd-77b2-40da-a210-9a7f1bd952dd","advice":"Driving","tag":"unsafe","description":"

It is not known whether it is safe to consume alcohol with Bufatas IV 60mg Injection. Please consult your doctor.

","imageUrl":"https://assets.mrmed.in/others/file-1674132431331-421990512-Driving.jpg"},{"id":"d0041f3c-9a1f-4bb0-bec0-f61a07b2591e","advice":"Pregnancy","tag":"unsafe","description":"

If you are pregnant or planning to get pregnant, ask your doctor or pharmacist for advice before taking this medicine. This medicine can cause infertility. It applies to men and women because Bufatas IV 60 mg injection may harm your sperm or eggs. It may have harmful effects on your baby.

","imageUrl":"https://assets.mrmed.in/others/file-1674132401469-949914510-Pregnancy.jpg"}]}},{"id":"37201920-28b7-4cf1-8d45-421dd9453d01","type":"PARA","position":8,"content_placement":1,"data":{"heading":"Side Effects of Bufatas IV 60mg Injection","text":"

Side effects are unwanted symptoms caused by medicines. Even though all medications cause side effects, not everyone gets them. Bufatas IV 60 mg injection causes the following side effects

Severe

Myelosuppression (decreased bone marrow activity)

Common side effects

Thalassemia
Skin rashes
Hair loss
Patches of dark skin
Blood in urine
Decrease in the number of blood cells and platelets
Nausea and vomiting
Jaundice
Infertility and sterility
Pneumonia Syndrome
Itching

"}},{"id":"ef2f2c26-4d37-4ed2-b247-44b06b71a9f1","type":"PARA","position":9,"content_placement":1,"data":{"heading":"Word of Advice","text":"

Inform the doctor if the patient has taken radiotherapy priorly to the treatment. If you have any other medical conditions like heart disease, lung, kidney, or liver problems. Tell your doctor if you have any symptoms of gout (pain and swollen joints caused by uric acid crystals). During or after administration of the injection, if you face itchy skin, fever, excessive sweating, rigors or chills, or difficulty in breathing, inform your doctor immediately.

"}},{"id":"4dd7dc0c-f0d1-48f9-bdf8-7cec3e660a3a","type":"FAQ","position":10,"content_placement":2,"data":{"heading":"FAQs about Bufatas IV 60mg Injection","faq_list":[{"id":"ea350427-f4d0-4e02-b2fb-ff9bf80832a6","question":"

Can Bufatas IV 60 mg injection cause infertility?

","answer":"

Yes, Bufatas IV 60 mg injection can cause infertility in men and women because it affects the sperm cells and egg. Consult the doctor before taking this medication.

"},{"id":"b0eb28c7-486e-4b5c-80c5-116a5799692a","question":"

How is Bufatas IV 60 mg injection administered?

","answer":"

Bufatas IV 60 mg injection form is given through an intravenous route into the vein by healthcare professionals.

"},{"id":"415966c3-f71f-4ebf-8d76-c223e8b6a25e","question":"

Can Bufatas IV 60 mg injection be used during pregnancy?

","answer":"

No, it is highly unsafe to use this medication during pregnancy as it can cause harmful effects on the developing fetus.

"},{"id":"3e39f962-f766-4bb3-af30-720432adae9d","question":"

Are there any special precautions patients should be aware of before starting treatment?

","answer":"

Patients should inform the physician about the pregnancy, breastfeeding or planning for a family. Patients should also inform about past medical and medication history.

"},{"id":"e32ff1cd-8b61-4390-bd06-e07ca0ebb743","question":"

What is the package insert that comes with Bufatas IV 60 mg injection?

","answer":"

The package insert contains all the scientific information (indications, uses, side effects, safety and warning, contraindications) about the drug.

"},{"id":"f64ea347-340b-44c3-8c2f-218759fc307b","question":"

Does Bufatas IV 60 mg injection cause permanent hair loss?

","answer":"

Yes, Bufatas IV 60 mg injection causes hair loss. Consult the physician about excessive hair loss

"},{"id":"6c52d6e1-f546-480f-b072-d832fde5ede4","question":"

What does Bufatas IV 60 mg injection look like?

","answer":"

Bufatas IV 60 mg injection comes in clear glass vials containing 60 mg of the drug in a 10 ml sterile solution.

"}]}},{"id":"5fdeef1d-2ca4-4b03-83fc-cd79a1f3533c","type":"PARA","position":11,"content_placement":3,"data":{"heading":"Fact Box of Bufatas IV 60mg Injection","text":"

Molecule Name: Busulfan

Therapeutic class: Anticancer

Pharmacological class: Alkylating agent - Alkyl sulfonates

Indication:

1. Chronic myelogenous leukemia

2. Hematopoietic progenitor cell transplantation

3. Polycythaemia vera

4. Thrombocythemia

5. Myelofibrosis

6. Hemoglobinopathies

7. Congenital metabolic diseases

"}},{"id":"1efec741-bda4-4061-a601-87ec7a3c656b","type":"PARA","position":12,"content_placement":3,"data":{"heading":"References","text":"

Aspen, Electronic Medicines Compendium(EMC) (Revised on: July 2020) https://www.medicines.org.uk/emc/product/4653/pil#gref (Accessed: December 14, 2022).
Busulfan (Revised on: May 19, 2015) National Cancer Institute. https://www.cancer.gov/about-cancer/treatment/drugs/busulfan (Accessed: December 14, 2022).
Anton Wellstein, Giuseppe Giaccone, Michael B. Atkins, and Edward A. Sausville, Pharmacotherapy of Neoplastic disease: cytotoxic drugs, Goodman & Gilman’s Pharmacological Basis of Therapeutics, 13th Edition, 2018, 1167-1174.
Buggia I, Locatelli F, Regazzi MB, Zecca M. Busulfan. Ann Pharmacother. 1994 Sep;28(9):1055-62. doi: 10.1177/106002809402800911. PMID: 7803883.

"}},{"id":"5b6678cc-1faa-4ba6-8a70-b587ef1f1089","type":"DISCLAIMER","position":13,"content_placement":5,"data":{"heading":"Disclaimer","text":"

MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.

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