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Calquence 100mg Capsule
Prescription Required
Salt Composition : Acalabrutinib
Manufacturer : ASTRAZENECA PHARMA INDIA LTD
Origin of Medicine : United Kingdom
12 Capsule (s) In A Box
PAP Information : Buy 12 Capsules, Get 48 Capsules Free. Contact us for latest updates.
Program Overview: ASTRAZENECA PHARMA INDIA LTD, Patient Assistance Program (PAP) is dedicated to helping patients in need of Calquence 100 mg Capsule. The program aims to provide eligible patients with access to the medication at a more affordable cost.
Program Benefits: Purchase 12 capsules of Calquence 100 mg Capsule, and you will receive 48 capsules free. Therefore, if eligible, you will have to pay only Rs.1,41,000 for 60 capsules of five boxes which is Rs. 28,200 per box of 12 capsules.
With MrMed's MRP discount of Rs. 40765 per box of 12 capsules and Astrazeneca's PAP program, the overall savings is about Rs.7 lakh 68 thousand per purchase.
Contact us for the latest updates on this exclusive offer.
Eligibility Criteria: To qualify for the Calquence Patient Assistance Program (PAP), you must meet specific criteria, including having a valid prescription for Acalabrutinib 100 mg from a medical oncologist and being an Indian patient with a valid identity card. Eligibility is determined based on the diagnosed condition and program-specific requirements.
Contact Information: If you have any questions or need assistance with the application process, our dedicated patient support team is here to help. You can reach us by phone at 89391 69999 or email us at [email protected].
Please note that MrMed is not involved in the PAP program. They offer free consultations to patients to provide information about the program. Patients eligible for the PAP program by Astrazeneca can avail of it without having to purchase the medication from MrMed.
Patient Assistance Programs
Program Overview: ASTRAZENECA PHARMA INDIA LTD, Patient Assistance Program (PAP) is dedicated to helping patients in need of Calquence 100 mg Capsule. The program aims to provide eligible patients with access to the medication at a more affordable cost.
Program Benefits: Purchase 12 capsules of Calquence 100 mg Capsule, and you will receive 48 capsules free. Therefore, if eligible, you will have to pay only Rs.1,41,000 for 60 capsules of five boxes which is Rs. 28,200 per box of 12 capsules.
With MrMed's MRP discount of Rs. 40765 per box of 12 capsules and Astrazeneca's PAP program, the overall savings is about Rs.7 lakh 68 thousand per purchase.
Contact us for the latest updates on this exclusive offer.
Eligibility Criteria: To qualify for the Calquence Patient Assistance Program (PAP), you must meet specific criteria, including having a valid prescription for Acalabrutinib 100 mg from a medical oncologist and being an Indian patient with a valid identity card. Eligibility is determined based on the diagnosed condition and program-specific requirements.
Contact Information: If you have any questions or need assistance with the application process, our dedicated patient support team is here to help. You can reach us by phone at 89391 69999 or email us at [email protected].
Please note that MrMed is not involved in the PAP program. They offer free consultations to patients to provide information about the program. Patients eligible for the PAP program by Astrazeneca can avail of it without having to purchase the medication from MrMed.
Introduction to Calquence 100mg Capsule
Calquence 100mg Capsule is an anticancer medicine containing the active constituent Acalabrutinib. It belongs to a class of drugs called Bruton's tyrosine kinase (BTK) inhibitors. It is used to treat mantle cell lymphoma (MCL), chronic lymphocytic leukemia (CLL), and small lymphocytic lymphoma (SLL). MCL, CLL, and SLL are cancers of the white blood cells called lymphocytes that are part of the immune system. They differ from each other by the location where cancer occurs and the type of lymphocytes affected.
Before taking this medicine, inform your doctor if you have had recent surgery, bleeding problems, heart rhythm problems, infection, pregnancy, or breastfeeding. It is not recommended for children and adolescents less than 18 years. This medicine can increase the risk of bleeding. Patients taking Calquence 100mg Capsule should be monitored for signs of bleeding and should avoid taking other medications that can increase the risk of bleeding, such as blood thinners.
Uses of Calquence 100mg Capsule
The Calquence 100mg Capsule is used in the treatment of
- Chronic lymphocytic leukemia
- Small lymphocytic lymphoma
- Mantle cell lymphoma
Therapeutic Effects of Calquence 100mg Capsule
The therapeutic effect of Calquence 100mg Capsule is to inhibit the activity of Bruton's tyrosine kinase (BTK). This protein is essential for the survival and growth of cancer cells in certain types of lymphomas and leukemias. By blocking BTK, it can help to slow down or even stop the growth and spread of cancer cells, which can lead to a reduction in tumor size, an improvement in symptoms, and a delay in disease progression.
Interaction of Calquence 100mg Capsule with other drugs
Inform your healthcare provider about all your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Calquence 100mg Capsule and reduce effectiveness by causing undesirable side effects.
More Information about Calquence 100mg Capsule
- Store in a refrigerator between 20°C to 25°C (68°F to 77°F).
- Keep away from moisture, heat, and light.
- It should not be frozen.
- Keep it in its original packaging until it is ready to be used.
- Keep out of the reach of children and pets.
How to consume Calquence 100mg Capsule
Calquence 100mg Capsule is typically taken orally, with or without food. The tablets should be swallowed whole, not crushed, chewed, or broken. The recommended dosage can vary depending on the type of cancer being treated and other factors such as your overall health and response to treatment. Do not take a double dose to make up for a missed dose.
Safety Advices for Calquence 100mg Capsule
Pregnancy
Calquence 100mg Capsule is not safe during pregnancy. It can harm the developing fetus, so pregnancy should be avoided while taking this medicine.
Breast Feeding
It is unknown whether Calquence 100mg Capsule is excreted into human breast milk, so breastfeeding women should consult a doctor before taking it.
Lungs
If you have a lung disease or lung cancer and are considering treatment with Calquence 100mg Capsule, it is important to discuss this medication's potential benefits and risks with your healthcare provider.
Liver
Calquence 100mg Capsule can affect the liver and causes elevation of liver enzymes (AST, ALT) in some patients. In rare cases, severe liver injury or failure has been reported.
Alcohol
Patients taking Calquence 100mg Capsules avoid or limit their alcohol consumption, as alcohol can exacerbate certain side effects of the medication, such as fatigue and depression.
Driving
Patients should always monitor their response to the Calquence 100mg Capsule medication and be cautious when driving or operating machinery if they experience any side effects that may impair their ability to do so safely.
Side Effects of Calquence 100mg Capsule
Like all medications, Calquence 100mg Capsules cause some side effects, although not everyone will experience them.
Serious:
- Bleeding problems (bruising or bleeding)
- Infections (pneumonia and sepsis)
- High blood pressure
- Heart problems (irregular heartbeat and chest pain)
- Kidney failure
Common:
- Headache
- Diarrhea
- Nausea
- Fatigue
- Muscle and joint pain
- Bruising or bleeding easily
- Upper respiratory tract infection
- Rash or itching
Word of Advice
If you have been prescribed Calquence 100mg Capsule, it is important to carefully read and understand the warnings and precautions associated with the medication. Patients require monitoring for signs of an allergic reaction. It can cause high blood pressure. Patients should check their blood pressure regularly. Report to your doctor if you develop a lesion or change in the appearance of an area on the skin. It increases the risk of infection, so patients should avoid close contact with infected persons. Patients with diabetes require close monitoring during treatment. Pregnancy and breastfeeding should be avoided during treatment. Always maintain a healthy and balanced diet to support your overall health and well-being.
FAQs
Q 1. Can I take Calquence 100mg Capsule if I have a history of bleeding disorders?
Patients with a history of bleeding disorders may be at an increased risk of bleeding while taking Calquence 100mg Capsule. Before starting treatment, your healthcare provider will evaluate your bleeding risk and may recommend additional monitoring or precautions.
Q 2. Can I take Calquence 100mg Capsule if I have a history of heart disease?
Calquence 100mg Capsule can cause cardiac effects, including irregular heartbeat and atrial fibrillation. Patients with a history of heart disease should be closely monitored while taking it. Your healthcare provider may recommend additional monitoring or precautions.
Q 3. How will this medication affect my blood?
Calquence 100mg Capsule can affect your blood in several ways. It may cause a decrease in the number of red blood cells, white blood cells, and platelets. This can lead to anemia, infections, and an increased risk of bleeding. Your healthcare provider will monitor your blood counts before and during treatment.
Q 4. Can I take this medication if I have diabetes?
Calquence 100mg Capsule can be taken by patients with diabetes, but it is important to monitor blood sugar levels closely while taking this medication. It can cause an increase in blood sugar levels in some patients, which may require adjustments in diabetes medications or insulin dosages.
Q 5. Can I go for Tooth extraction while taking this medication?
Patients taking Calquence 100mg Capsule should inform their dentist and healthcare provider if they need a tooth extraction or any other dental procedures. This is because it can increase the risk of bleeding and impair wound healing. Your dentist and healthcare provider may recommend temporarily stopping treatment before the dental procedure to reduce the risk of bleeding.
Fact Box of Calquence 100mg Capsule
Molecule name: Acalabrutinib | Therapeutic class: Antineoplastic |
Pharmacological class: Bruton's tyrosine kinase (BTK) inhibitors | Indications: 1. Chronic lymphocytic leukemia 2. Small lymphocytic lymphoma 3. Mantle cell lymphoma |
References
- AstraZeneca, Electronica medicines compendium (EMC), [Revised on Dec 2020], [ Accessed on 5th May 2023], https://www.medicines.org.uk/emc/files/pil.11917.pdf
- AstraZeneca, US Food and Drug Administration, [ Revised on Oct 2017], [ Accessed on 5th May 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/210259s000lbl.pdf
- John C Byrd et al; Acalabrutinib monotherapy in patients with relapsed/refractory chronic lymphocytic leukemia: updated phase 2 results; Blood; Published on April 2020; [Accessed on5th May 2023]; https://pubmed.ncbi.nlm.nih.gov/31876911/
Disclaimer
MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.
