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19% Off

Chemoblast 10mg Injection

Prescription Required

cold-chain

Salt Composition : Vinblastine

Manufacturer : NEON LABORATORIES LTD

Origin of Medicine : India

MRP: â‚ą213.5
Price : â‚ą174
You Save : â‚ą40 (19%)

1 Vial(s)

Prepaid Only. Non-Returnable


Introduction to Chemoblast 10mg Injection

Chemoblast 10mg injection is an anti-cancer drug belonging to the class of mitotic inhibitors, containing the active ingredient vinblastine. This medication is used in combination with other medicines for the treatment of Hodgkin’s and non-Hodgkin’s lymphoma, testicular cancer, breast cancer, and kaposi’s sarcoma. Hodgkin’s disease and non-Hodgkin’s disease refers to the type of blood cancers. 

This injection should be used with caution in patients with a history of nerve damage, respiratory disease, or gastrointestinal disorders. Special care is needed if you are taking other medicines, as some could interact with this drug. For example the use of erythromycin may increase the side effects of this drug. In case if you are undergoing radiotherapy in the liver area, your doctor will delay giving you this medicine. During the treatment, your doctor may periodically monitor your white blood cell counts, platelets, blood sugar, electrolytes and kidney parameters to prevent serious complications. This medicine has the potential to cause heart problems when combined with other anticancer medicine like bleomycin or cisplatin. Report to your doctor if you experience any hypersensitive reactions like itchy skin or rashes, while taking this medicine.

As there is a risk of birth defects, women of childbearing potential should use effective contraception methods during treatment with this drug. If you're pregnant or breastfeeding women, you may plan to have a baby or think you may be pregnant. Please consult with your doctor for more advice before taking this medicine. Do not drive or use machines if you experience any side effects which may lessen your ability to do so. It is advised not to use this injection if you are allergic to this drug or any of its ingredients, in case you have a bacterial infection which is not under control, and if your blood tests show that you do not have enough WBC to fight infection. This drug may lead to changes in your blood cells, so your doctor will take blood samples to monitor for these and also to check how well your liver is working. Inform to the doctor if you have been diagnosed with liver disorders, heart failure, high blood cholesterol levels, or hypertension before starting this treatment.


Uses of Chemoblast 10mg Injection

Chemoblast 10mg injection has been indicated for treating,

  • Hodgkin’s lymphoma
  • Non-Hodgkin’s lymphoma
  • Testicular cancer
  • Breast cancer
  • Kaposi’s sarcoma

Therapeutic Effects of Chemoblast 10mg Injection

It works by disrupting the formation of microtubules in cells. Microtubules are structures that help to support and shape cells, as well as transport molecules within cells. In cancer cells, microtubules play a key role in cell division and growth. By interfering with microtubule formation, this drug disrupts the ability of cancer cells to divide and grow, ultimately leading to their death.


Interaction of Chemoblast 10mg Injection with other drugs

Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Chemoblast 10mg injection and reduce effectiveness by causing undesirable side effects.


More Information about Chemoblast 10mg Injection

  • Store Chemoblast 10mg injection in the refrigerator at (2°C to 8°C).
  • Keep it out of reach from children.

How to consume Chemoblast 10mg Injection

It should only be administered by a trained doctor or nurse experienced in giving chemotherapy. This medication is injected directly into a vein through a needle or catheter. Do not self-administer the injection. Your doctor will decide the dose and duration of the treatment based on your disease severity and other factors.


Safety Advices for Chemoblast 10mg Injection

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Pregnancy

  

Chemoblast 10mg injection is not recommended for pregnant women as it may cause fetal harm. Consult your doctor if you are pregnant or planning for pregnancy during the treatment.

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Breast Feeding

  

Breastfeeding is not recommended in patients taking Chemoblast 10mg injection because the medicine passes into the breast milk in small amounts and may harm your baby.

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Lungs

  

It is not known whether Chemoblast 10mg injection can be administered to patients with lung problems. Consult your doctor if you have any lung diseases before starting the treatment.

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Liver

  

Inform your doctor if you have any liver problems before taking Chemoblast 10mg injection. Regular monitoring of liver function tests is recommended.

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Alcohol

  

Consuming alcohol may affect the effectiveness of Chemoblast 10mg injection. Stop consuming alcohol if you are taking this medicine.

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Driving

  

It is unsafe to drive vehicles or operate heavy machinery after taking Chemoblast 10mg injections, it may cause dizziness and impair your concentration.


Side Effects of Chemoblast 10mg Injection

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

Serious

  • Severe allergic reactions (difficulty in breathing or swallowing, swelling of hands, feet, lips, mouth, or throat, itchy rash)
  • Swelling or pain at the site of injection (during or immediately after the injection)

Common

  • Low blood counts
  • Convulsions
  • Mental depression
  • Tiredness
  • Diarrhea
  • Loss of appetite
  • Nausea, vomiting
  • Stomach cramps
  • Hair loss

Word of Advice

This medicine can weaken the immune system, making patients more susceptible to infections. Patients should take steps to avoid contact with sick people and practise good hygiene, such as washing their hands frequently. Patients should also avoid activities that could increase their risk of injury or bleeding, such as contact sports or using sharp objects. This drug makes the skin more sensitive to sunlight, leading to sunburn, blistering, or skin discoloration. It's important to use sunscreen and protective clothing while being exposed to sunlight. It is recommended to limit your alcohol intake or avoid it altogether while taking Chemoblast 10mg injection.


FAQs

Q 1. Can I drink alcohol while taking a Chemoblast 10mg injection?

It is generally recommended to avoid drinking alcohol while taking Chemoblast 10mg injection, as alcohol can increase the risk of side effects such as nausea, vomiting, and liver damage.

Q 2. Does Chemoblast 10mg injection cause hair loss?

Hair loss from Chemoblast 10mg is usually temporary, and hair growth typically resumes after treatment is completed.

Q 3. What happens to cancer cells when given Chemoblast 10mg injection?

Chemoblast 10mg injection works by stopping the cancer cells from separating into 2 new cells. So it blocks the growth of cancer.

Q 4. What are the precautions of Chemoblast 10mg injection?

Check with your doctor immediately if you notice any unusual bleeding or bruising, black stools, blood in urine, or pinpoint red spots on your skin. Be careful when using sharp objects or participating in activities that may result in injury.

Q 5. How is Chemoblast 10mg injection excreted?

Chemoblast 10mg injection is primarily metabolised in the liver, and its elimination from the body is mainly through the bile and faeces. Only a small amount of the drug is eliminated through the urine.

Q 6. What are the side effects of Chemoblast 10mg injection on skin?

This drug can make the skin more sensitive to sunlight, leading to sunburn, blistering, or skin discoloration. It's important to use sunscreen and protective clothing while being exposed to sunlight.


Fact Box of Chemoblast 10mg Injection

Molecule name: Vinblastine

Therapeutic class: Anti-cancer

Pharmacological class: Mitotic inhibitors

Indications: 

1. Hodgkin’s lymphoma

2. Non-Hodgkin’s lymphoma

3. Testicular cancer

4. Breast cancer

5. Kaposi’s sarcoma


References

  1. Hospira UK Limited, Electronic medicines compendium (EMC), [Revised on Sept 2020][ Accessed on 4th April 2023], https://www.medicines.org.uk/emc/files/pil.1422.pdf
  2. DBL vinblastine injection - pfizer. Available at: https://labeling.pfizer.com/ShowLabeling.aspx?id=12288 [ Accessed on 4th April 2023].
  3. Vinblastine injection -NPS MedicineWise. Available at: https://www.nps.org.au/assets/medicines/aea96da5-9c46-482b-9add-a53300ff05d1.pdf   [ Accessed on 4th April 2023].
  4. HY Yap; Vinblastine given as a continuous 5-day infusion in the treatment of refractory advanced breast cancer; Cancer Treatment Reports; Published on March 1980;[ Accessed on 4th April 2023]; https://pubmed.ncbi.nlm.nih.gov/7407762/
  5. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Cytotoxic agents, 12th edition, 2011, 1706.
  6. KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs, 7th edition, 2013, 865.

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