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COLSTIM 30MIU INJECTION_1
COLSTIM 30MIU INJECTION_2
COLSTIM 30MIU INJECTION_1
28% Off

Colstim 30miu Injection

Prescription Required

cold-chain

Salt Composition : Filgrastim

Manufacturer : ZYDUS CADILA

Origin of Medicine : India

MRP: 495
Price :354
You Save :141 (28%)

1 Prefilled Syringe(s) Of 1ml

Prepaid Only. Non-Returnable


Introduction to Colstim 30miu Injection

Colstim 30MIU injection contains the active constituent filgrastim. It is a white blood cell growth factor (granulocyte-colony stimulating factor) approved by the FDA to decrease the risk of developing febrile neutropenia ( occurrence of fever or infection associated with low WBC count) and to reduce the duration of neutropenia (low white blood cell count) in people who have non-myeloid cancer and are receiving chemotherapy drugs. It is also used to increase the number of WBC and decrease the length of time of fever in people with acute myeloid leukemia. 

It is also used in people undergoing bone marrow transplants and in people with severe chronic neutropenia (low number of neutrophils in the blood). Colstim 30MIU injection is also used to prepare the blood for leukapheresis (a treatment in which certain blood cells are removed from the blood). It is also indicated to increase the chance of survival in people exposed to harmful amounts of radiation, which can cause severe damage to the bone marrow. Other uses include in patients with advanced HIV infection, which will help to reduce the risk of infections. 

Colstim 30MIU injection belongs to the class of medications called colony-stimulating factors. They work by helping the body to produce more White blood cells. WBC are important because they help your body fight infection. These cells are highly sensitive to the effects of chemotherapy, which might cause a decrease in the number. If your WBC decreases, your body may not have enough cells to combat bacteria, putting you at risk of infection. Inform your physician if you have or had liver disease, kidney problems, sickle cell anemia, or bone disease. Common side effects include fever, pain, rash, cough, shortness of breath, and nosebleed.


Uses of Colstim 30miu Injection

  • To prevent infections after chemotherapy due to decreased white blood cells (neutropenia)

Therapeutic Effects of Colstim 30miu Injection

Colstim 30MIU injection is a colony-stimulating factor that acts on blood-forming cells by binding to specific cell surface receptors, thereby inducing cell division, multiplication, and cell functional activation. 


Interaction of Colstim 30miu Injection with other drugs

Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Colstim 30MIU injection and reduce effectiveness by causing undesirable side effects. 


More Information about Colstim 30miu Injection

  • Store Colstim 30MIU injection in a refrigerator (2°C – 8°C). Do not freeze.
  • Do not shake the pre-filled syringe.
  • Discard the medicine if stored at room temperature for more than 48 hours.
  • Keep it out of reach from children and pets.
  • It is important to get the dose at the scheduled time. If you missed the schedule, contact your doctor immediately for advice.

How to consume Colstim 30miu Injection

Colstim 30MIU injection  is available as a prefilled syringe and solution for injection. A qualified healthcare professional will administer the injection in the fatty tissues just under your skin (subcutaneously) or it will be administered as an intravenous injection into your vein slowly. The dose, route of administration, and frequency will be decided by your doctor based on your disease condition and other factors.  

If your physician decides that you or your caregiver can administer the Colstim 30MIU injection prefilled syringe at home, then read the “Instructions for use” carefully from the package insert with the medicine. Your doctor or other healthcare professionals will train you on self-administration. Do not administer the medicine if you have not been trained and are not sure about the administration procedure. 


Safety Advices for Colstim 30miu Injection

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Pregnancy

  

Colstim 30MIU injection is unsafe when administered during pregnancy because it may cause birth defects in your baby. Consult your doctor if you are pregnant or planning for pregnancy during the treatment.

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Breast Feeding

  

It is unsafe to breastfeed during the treatment with this Colstim 30MIU injection because it may cause harm to the baby. Please consult your doctor before breastfeeding. 

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Lungs

  

It is unknown whether Colstim 30MIU injection Injection can be administered to patients with lung problems. Consult your doctor if you have any lung diseases before starting the treatment.

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Liver

  

It is unknown whether Colstim 30MIU injection can be administered in patients with liver disorders. Inform your physician if you have any liver problems before starting treatment with this Injection. 

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Alcohol

  

It is unsafe to consume alcohol with Colstim 30MIU injection injection. Please consult your doctor for more advice.

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Driving

  

It is unsafe to travel, drive vehicles, or operate heavy machinery after taking (1 hour)  Colstim 30MIU injection pre-filled Injection. Please consult your doctor. 


Side Effects of Colstim 30miu Injection

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

 Common

  • Pain in the bones, joints, and muscles
  • Pain at the site of Injection
  • Fever
  • Itchiness and skin rash
  • Nausea
  • Headaches
  • Dizziness and tiredness
  • Nose bleeding
  • Hair fall 

 Serious

  • Inflammation of Aorta
  • Capillary leak syndrome (plasma leaks out of tiny blood vessels)
  • Hypersensitivity reactions
  • Changes in urine color
  • Swelling in hands, feet, face, and abdomen
  • Difficulty in breathing
  • Sickle cell anemia

Word of Advice

Inform your physician if you are experiencing any symptoms of swelling in the face, feet, hands, and abdomen, difficulty in breathing, sudden drop in blood pressure, left abdominal pain, weakness, and skin rashes. If you use the prefilled syringe, allow the medicine to warm for 30 minutes at room temperature before injecting. Read the package insert carefully if you are self-administering the medicine. This medicine may cause lung, liver, or kidney problems. Your physician may advise you to take laboratory tests regularly to monitor the effectiveness of the therapy.


FAQs

Q 1. What are the symptoms that I should notify the physician while taking Colstim 30MIU injection?

Inform your physician if you are experiencing any symptoms of swelling in the face, feet, hands, and abdomen, difficulty in breathing, sudden drop in blood pressure, left abdominal pain, weakness, and skin rashes.

Q 2. What is the Colstim 30MIU injection package insert?

The FDA provides a package insert, which summarizes the relevant scientific information needed for healthcare practitioners and patients to use the drug safely and effectively. The package insert contains safety information, instruction for use, and other information.

Q 3. Who should not take Colstim 30MIU injection?

Colstim 30MIU injection is not indicated for everyone. Do not take this medicine if you are allergic to any forms of rubber, latex, pegfilgrastim, filgrastim or any of the other ingredients in this medicine.

Q 4. Will Colstim 30MIU injection affect my kidneys?

This medicine may affect your kidneys. Regular kidney function tests will be taken to monitor your kidney functions. Inform your physician if you have any kidney problems.

Q 5. Can I breastfeed while taking Colstim 30MIU injection?

No, This medicine secretes in small amounts in breast milk. Colstim 30MIU injection can cause harm to your baby. Please consult your doctor if you are breastfeeding.


Fact Box of Colstim 30miu Injection

Molecule name: Filgrastim

Therapeutic class: Hematopoietic

Pharmacological class: colony-stimulating factor

Indications:  Neutropenia


References

  1. Neupogen Singleject 30 MU (0.6 mg/ml) - Patient Information Leaflet (PIL) - (emc) ww.medicines.org.uk. [Revised on 2022] [cited 2023 Mar 14]. Available from: https://www.medicines.org.uk/emc/product/608/pil
  2. Neupogen 30 MU (0.3 mg/ml) solution for injection - Patient Information Leaflet (PIL) - (emc). www.medicines.org.uk. [Revised on 2022] [cited 2023 Mar 14]. Available from: https://www.medicines.org.uk/emc/product/3000/pil
  3. KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs, 7th edition, 2013, 876

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