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Salt Composition : Ramucirumab


Origin of Medicine : United States of America

MRP: 257532
Price :213288
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PAP Information :    Buy 1st dose, Get the next two doses free. Contact us for latest updates.

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Get financial assistance directly from pharma companies and cover your cost of medicines or get free medicines for the eligible patient with patient assistance programs (PAP). We provide proper guidance assistance to patients getting enrolled in the patient assistance program.

Introduction to Cyramza 500mg Injection

Cyramza 500mg Injection is an anticancer medication containing the active ingredient Ramucirumab. It is a monoclonal antibody drug. Cancer is a condition in which cells multiply uncontrolled and abnormally. This medication treats advanced cancers of the stomach, colon, rectum, lungs, and liver. It may be given alone or in combination with other anticancer medications to treat various types of cancer. The benefits of Cyramza 500mg Injection are that it can help to slow down the growth and spread of cancer cells in various types of cancer. Studies have shown that this medication can improve survival rates and increase the time until cancer progresses to the advanced stage.

As with any medication, this medication can cause side effects, including high blood pressure, fatigue, nausea, vomiting, and diarrhea. Inform your doctor if you have high blood pressure, bleeding problems, liver disorders, kidney disorders, lung cancer, or are going to have surgery before taking this medication. This medication is not recommended for adolescents and children under 18.

Uses of Cyramza 500mg Injection

  • Advanced gastric cancer
  • Gastroesophageal junction adenocarcinoma
  • Non-small cell lung cancer
  • Hepatocellular carcinoma
  • Colorectal cancer

Therapeutic Effects of Cyramza 500mg Injection

Cyramza 500mg Injection is a monoclonal antibody drug used in the treatment of various types of cancer. It works by targeting and inhibiting the action of a protein called vascular endothelial growth factor receptor 2 (VEGFR2), which plays a key role in the growth and development of blood vessels that feed tumors. By blocking VEGFR2, this medication prevent cancer cell growth and spread.

Interaction of Cyramza 500mg Injection with other drugs

You should tell the doctor about all the medicines you take, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Cyramza 500mg Injection and reduce effectiveness by causing undesirable side effects.

More Information about Cyramza 500mg Injection

  • Cyramza 500mg Injection should be stored according to the manufacturer's instructions and in compliance with local regulations.
  • Stored in a refrigerator at a temperature between 2°C and 8°C (36°F and 46°F).
  • Do not freeze or shake the drug.
  • Keep in its original packaging until ready to use.
  • After reconstitution, use immediately or within 4 hours if stored at room temperature or within 24 hours if stored in a refrigerator.

How to consume Cyramza 500mg Injection

Cyramza 500mg Injection is administered by a healthcare professional through intravenous injection in a hospital or clinic setting. It is not intended for self-administration. The recommended dosage and frequency depends on the type and stage of the cancer being treated, the individual patient's medical history, and overall health status. The drug is usually administered with chemotherapy or as a standalone treatment.

If you miss a scheduled dose, contact your healthcare provider as soon as possible to discuss the best course of action. Sometimes, your healthcare provider may recommend that you receive the missed dose as soon as possible and then resume the regular dosing schedule. However, this will depend on several factors, such as how long it has been since your last dose, overall health status, and cancer stage. It is important not to double the dose to make up for a missed dose, as this can increase the risk of side effects.

Safety Advices for Cyramza 500mg Injection

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Cyramza 500mg Injection is unsafe for pregnant women as it may cause fetal harm. It is not recommended to take it during pregnancy.

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Breast Feeding


It is unknown if Cyramza 500mg Injection  is excreted in human milk. So breastfeeding women should consult a doctor before starting with this medication.

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Cyramza 500mg Injection has been associated with some lung-related side effects, although these are relatively uncommon. Consult your doctor if you have any lung diseases before starting the treatment.

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Regular monitoring of liver function tests is recommended because Cyramza 500mg Injection  has been associated with liver injury in some patients. It is important to monitor liver function regularly in patients taking, particularly those with pre-existing liver disease or a history of liver problems.

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It is generally recommended that patients taking Cyramza 500mg Injection  avoid or limit their alcohol intake, as alcohol can increase the risk of liver damage and exacerbate any liver-related side effects of this medication.

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Cyramza 500mg Injection may cause side effects such as fatigue, dizziness, or blurred vision, impairing a patient's ability to drive or operate machinery safely. So you should avoid these activities during treatment.

Side Effects of Cyramza 500mg Injection

Side effects are unwanted symptoms that occur due to medicines. Even though all drugs cause side effects, not everyone gets them.


  • Blood clots
  • Impaired wound healing
  • Serious infusion reactions
  • Kidney problems
  • Hepatotoxicity (liver damage)
  • Pulmonary hemorrhage (bleeding from the lungs)


  • High blood pressure
  • Fatigue
  • Decreased appetite
  • Nausea and vomiting
  • Diarrhea
  • Mouth sores
  • Abdominal pain
  • Headache
  • Proteinuria (the presence of excess protein in the urine)
  • Hypothyroidism (an underactive thyroid gland)
  • Gastrointestinal bleeding
  • Nosebleeds
  • Bruising

Word of Advice

If you are considering Cyramza 500mg Injection for cancer treatment, it is important to weigh the potential benefits against the risks and side effects and to discuss any concerns with your healthcare provider. While this medication can be an effective treatment option for certain types of cancer, it does come with some potential risks and precautions that should be carefully considered. This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. 

Maintain a healthy lifestyle to support your overall health and well-being during treatment. If you are pregnant or breastfeeding, discussing the potential risks and benefits of this medication with your healthcare provider before starting treatment is important. Effective contraception is recommended during treatment and at least 3 months after the last dose. Remember to communicate openly with your healthcare team and to seek support from loved ones and other resources as needed throughout your treatment journey.


Q 1. Can Cyramza 500mg Injection be used in patients with kidney disease?

Cyramza 500mg Injection should be used cautiously in patients with kidney disease, as it may affect kidney function. Kidney function tests should be monitored regularly during treatment, and the dosage may need to be adjusted based on the results.

Q 2. Can Cyramza 500mg Injection cause hair loss?

Hair loss is not a common side effect of Cyramza 500mg Injection. However, some patients may experience hair thinning or loss due to chemotherapy or other cancer treatments combined with this medication.

Q 3. Can Cyramza 500mg Injection cause fertility problems?

There is no evidence that Cyramza 500mg Injection causes fertility problems. However, it is recommended that women of childbearing age use effective contraception during treatment and for at least 3 months after the last dose, this injection may cause harm to a developing fetus.

Q 4. Can Cyramza 500mg Injection be used in elderly patients?

Yes, Cyramza 500mg Injection can be used in elderly patients. However, elderly patients may be more susceptible to certain side effects, such as bleeding or high blood pressure, and require more frequent monitoring.

Q 5. What food should I avoid while taking Cyramza 500mg Injection?

There are no specific foods that need to be avoided while taking Cyramza 500mg Injection. However, following a balanced and healthy diet is important to support your overall health during treatment.

Fact Box of Cyramza 500mg Injection

Molecule name: Ramucirumab

Therapeutic class: Anticancer

Pharmacological class: Monoclonal Antibody


1. Advanced gastric cancer

2. Gastroesophageal junction adenocarcinoma

3. Non-small cell lung cancer

4. Hepatocellular carcinoma

5. Colorectal cancer


  1. Eli Lilly Nederland B.V, Electronic medicines compendium (EMC), [Revised on July 2021] [ Accessed on 11th April, 2023],
  2. Eli Lilly and Company, US Food and Drug Administration, [Revised on May 2020] [ Accessed on 11th April, 2023],
  3. Goodman & Gilman's The Pharmacological Basis of Therapeutics, 13th edition, 2018, 1311-1312
  4. Cancer Chemotherapy and Biotherapy: Principles and Practice, 5th edition, 2018, 777-779


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