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Cytosorb Devices
Prescription Required
Salt Composition : Cytokine Removal
Manufacturer : BIOCON LTD
Origin of Medicine : India
1 Device(s)
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Introduction to Cytosorb Devices
Cytosorb device is a medical device used in critical care settings to remove inflammatory mediators from the bloodstream of patients with conditions such as sepsis, acute respiratory distress syndrome (ARDS), and cardiac surgery-associated inflammatory response syndrome (CARS). The body can produce excessive levels of cytokines in inflammation due to severe infection. This device removes these cytokine substances in your blood.
Cytosorb devices are used to treat patients aged 18 years and above with confirmed COVID-19 who are showing certain severe symptoms (including a persistent cough, high fever, developing more difficulty breathing). COVID-19 is a highly infectious disease caused by the SARS-CoV-2 virus. It is essential to inform your health care professional if you are pregnant or have any diseases or allergic conditions before starting treatment with Cytosorb devices.
Uses of Cytosorb Devices
Cytosorb devices use in the treatment of the following:
- Treatment of COVID-19 patients with severe symptoms
- Acute respiratory distress syndrome (ARDS)
- Cardiac surgery-associated inflammatory response syndrome (CARS)
Therapeutic Effects of Cytosorb Devices
Cytosorb devices work by using a process called hemoadsorption to remove inflammatory mediators from the bloodstream of critically ill patients. Hemoadsorption is a method of blood purification in which blood is passed through a cartridge containing adsorbent material that selectively removes certain substances from the blood. It contains highly porous polymer beads with a large surface area that can selectively adsorb a range of inflammatory mediators, such as cytokines, chemokines, and endotoxins.
Interaction of Cytosorb Devices with other drugs
Inform your healthcare provider about all your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Cytosorb devices and reduce effectiveness by causing undesirable side effects.
More Information about Cytosorb Devices
- Store at a cool temperature of 4°C and 30°C (39°F and 86°F).
- Do not freeze.
- Protected from light.
- Keep it in its original packaging until it is ready to be used.
- Keep out of the reach of children and pets.
- Should be disposed of properly.
How to consume Cytosorb Devices
Cytosorb devices should only be used by qualified healthcare professionals and require specialized medical training. It is a medical device used in critical care settings where a cartridge containing porous polymer beads is connected to the patient's circulation. Blood is circulated through the cartridge, and the inflammatory mediators are selectively adsorbed onto the surface of the beads.
Safety Advices for Cytosorb Devices
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Pregnancy
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There is limited information available that Cytosorb devices is used in pregnancy or not. So patients should consult their doctor if they are pregnant or planning to become pregnant.
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Breast Feeding
 ÂIt is unclear whether Cytosorb devices is excreted in human milk. So you should consult a doctor before taking this medication if you are a breastfeeding mother.Â
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Lungs
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In studies, it has been seen that Cytosorb devices does not cause any harm to the lungs. However, as with any medical treatment, there is always a potential risk of adverse effects.
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Liver
  Cytosorb device works by removing inflammatory mediators from the bloodstream and is not metabolized by the liver, it is considered relatively safe in the patient.
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Alcohol
 ÂThere is no known interaction between Cytosorb devices and alcohol. However, it is important to note that alcohol consumption can harm overall health and potentially exacerbate underlying medical conditions. So patients should consult their healthcare provider before taking alcohol during treatment.
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Driving
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Cytosorb devices may cause side effects such as dizziness, affecting a patient's ability to drive or operate heavy machinery. Patients should wait until their vision is normal before driving or operating machinery.
Side Effects of Cytosorb Devices
Like all medications, Cytosorb devices cause some side effects, although not every person who takes it will experience them.Â
Serious:
- Very low blood pressure
- Abnormal heart rhythm
- Bleeding
- Blood clotting
- Low platelet down
- Low levels of calcium and proteins in the blood
- Infection
- Allergic reactions
- Sepsis
- Anaphylactic shock
Common:
- Hypotension
- Fever
- Dizziness
- Lightheadedness
- Fainting
Word of Advice
If you are taking Cytosorb devices treatment, it is important to discuss any concerns or questions you may have with your healthcare provider. Pregnant and breastfeeding women should discuss their risk and benefit with the doctor. Be sure to provide your doctor with a complete medical history, including any medications you are taking and any pre-existing medical conditions you may have. Always follow the dosing instructions and precautions provided by your doctor, and report any side effects or adverse reactions to your healthcare provider as soon as possible. Never stop or modify your medication regimen without consulting your healthcare provider.
FAQs
Q 1. Can Cytosorb devices be reused or recycled?
No, Cytosorb devices is a single-use medical devices and should not be reused or recycled. Each device is intended for single-patient use and should be properly disposed of after treatment.
Q 2. Does Cytosorb device treatment have any effect on chemotherapy or radiation therapy?
No evidence suggests that Cytosorb device treatment interferes with chemotherapy or radiation therapy. However, patients undergoing cancer treatment should discuss the potential risks and benefits of treatment with their healthcare provider.
Q 3. Can Cytosorb devices be used in children?
Yes, Cytosorb devices can be used in children, although the dosing and administration may vary depending on the child's age and weight. Your child's healthcare provider will determine the appropriate dosing and treatment duration based on their medical needs.
Q 4. Can Cytosorb devices be used in patients with kidney or liver disease?
Cytosorb devices have been used in patients with kidney or liver disease and those with normal kidney and liver function. However, the safety and efficacy treatment in these patient populations may vary and depend on a case-by-case basis by a healthcare provider.
Q 5. Can Cytosorb devices be used in patients with bleeding disorders?
Cytosorb devices treatment may increase the risk of bleeding in some patients, particularly those with preexisting bleeding disorders or those taking blood-thinning medications. Patients with bleeding disorders should discuss the potential risks and benefits of treatment with their healthcare provider before undergoing treatment.
Q 6. Can Cytosorb devices be used in patients with heart failure or other cardiac conditions?
Cytosorb devices may be used in patients with heart failure or other cardiac conditions, but the safety and efficacy of treatment in these populations may vary. Your healthcare provider will determine whether the treatment is appropriate for your medical needs.
Q 7. Does Cytosorb device treatment require any special monitoring?
Patients undergoing Cytosorb device treatment may require special monitoring, including regular blood tests to monitor electrolyte levels and other indicators of organ function. Your healthcare provider will determine the appropriate monitoring schedule based on your medical needs.
Fact Box of Cytosorb Devices
Molecule name: Cytosorb removal | Therapeutic class: Blood purification device |
Pharmacological class:Â Extracorporeal cytokine adsorber
| Indications:Â 1. Treatment of COVID-19 patients with severe symptoms 2. Acute respiratory distress syndrome (ARDS) 3. Cardiac surgery-associated inflammatory response syndrome (CARS) |
References
- Cytosorbents, US Food and Drug Administration, [Updated on April 10, 2020], [ Accessed on 27th April 2023], https://www.fda.gov/media/136866/download
- Dina Ragab et al; The COVID-19 Cytokine Storm; What We Know So Far; Frontiers in Immunology [Published on 16/06/2020], [27th April 2023] https://www.frontiersin.org/articles/10.3389/fimmu.2020.01446/full
Disclaimer
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