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DABIGAT 110MG CAPSULE_1
DABIGAT 110MG CAPSULE_2
DABIGAT 110MG CAPSULE_3
DABIGAT 110MG CAPSULE_1
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Dabigat 110mg Capsule

Prescription Required

Salt Composition : Dabigatran Etexilate

Manufacturer : NATCO PHARMA LTD

Origin of Medicine : India

MRP: 326
Price :277
You Save :49 (15%)

10 Capsule(s) In A Strip

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Introduction to Dabigat 110mg Capsule

Dabigat 110mg capsule contains an active component such as Dabigatran etexilate. It is a medication used to prevent blood clots in individuals at risk of stroke due to atrial fibrillation, a type of irregular heartbeat, or for the treatment and prevention of blood clots like deep vein thrombosis (DVT) and pulmonary embolism (PE). It is an anticoagulant, which means it helps prevent the formation of blood clots by inhibiting the activity of thrombin, an enzyme responsible for blood clotting. Dabigat 110mg capsule is the prodrug form, which converts it into dabigatran in the body. 

Unlike warfarin, which requires frequent monitoring and dose adjustments based on INR (International Normalized Ratio) measurements, the Dabigat 110mg capsule has a fixed dosage regimen. This means that patients do not need regular blood tests to monitor its effectiveness, making it more convenient for patients and healthcare providers. It has a relatively quick onset of action, providing a more immediate anticoagulant effect than other anticoagulants.

Individuals with known hypersensitivity or allergy to the Dabigat 110mg capsule or any of its components should not use the medication. This medication is an anticoagulant that can increase the risk of bleeding. It is contraindicated in patients with active pathological bleeding, such as gastrointestinal bleeding, intracranial bleeding, or bleeding disorders. It is primarily eliminated through the kidneys. It is contraindicated in patients with severe renal impairment unless under specific circumstances where the benefits outweigh the risks and a dose adjustment is made.  It capsules contain lactose, and individuals with lactose intolerance should exercise caution while taking the medication. They should consult their healthcare provider if they experience any gastrointestinal symptoms after starting the medication.


Uses of Dabigat 110mg Capsule

Dabigat 110mg capsule is used in:

  • Prevention and treatment of blood clots

Therapeutic Effects of Dabigat 110mg Capsule

Dabigat 110mg capsule, as an anticoagulant, exerts its therapeutic effects by inhibiting the activity of thrombin, a key enzyme in the blood clotting process. By doing so, it helps prevent the formation of blood clots, reducing the risk of stroke and systemic embolism in patients with non-valvular atrial fibrillation. Additionally, it is effective in the treatment and prevention of deep vein thrombosis (DVT) and pulmonary embolism (PE). 


Interaction of Dabigat 110mg Capsule with other drugs

Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Dabigat 110mg capsule, reducing effectiveness by causing undesirable side effects. 


More Information about Dabigat 110mg Capsule

  • Store at room temperature, between 20°C to 25°C (68°F to 77°F).
  • Keep away from moisture, heat, and light.
  • It should not be frozen.
  • Keep away from children and pets.

How to consume Dabigat 110mg Capsule

To use Dabigat 110mg capsule effectively, follow your healthcare provider's prescribed instructions. Typically, it comes in capsule form and should be taken orally, with or without food, as directed. Swallow the capsule whole with a full glass of water to ensure proper absorption. Avoid breaking, crushing, or chewing the capsules, as it may interfere with the medication's effectiveness. The dosage and frequency of administration will depend on your medical condition, such as atrial fibrillation or deep vein thrombosis, and your health status. 


Safety Advices for Dabigat 110mg Capsule

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Pregnancy

  

Dabigat 110mg capsule is generally not recommended during pregnancy due to potential risks to the fetus. Pregnant women or those planning to become pregnant should discuss the risks and benefits of the medication with their healthcare provider.

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Breast Feeding

  

The safety of Dabigat 110mg capsule during breastfeeding is not well-established, and its use is generally not recommended. Breastfeeding women should consult their healthcare provider about the potential risks before using the medication.

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Lungs

  

If you have a lung condition and your healthcare provider has prescribed Dabigat 110mg capsule for another condition, it's essential to inform them about your lung condition and any other medical issues you may have. 

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Liver

  

If you have a liver condition or any concerns about the safety of Dabigat 110mg capsule in your specific case, it's crucial to discuss this with your healthcare provider. They can evaluate your liver function, consider your overall health status

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Alcohol

  

The use of alcohol while taking Dabigat 110mg capsule should be approached with caution. Alcohol can interact with medications, including anticoagulants like this medication, and may increase the risk of certain side effects.

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Driving

  

Dabigat 110mg capsule can cause certain side effects that may impair your ability to drive safely. These side effects can include dizziness, lightheadedness, blurred vision, and transient changes in heart rhythm. These effects can interfere with your concentration, alertness, and coordination, making driving potentially unsafe.


Side Effects of Dabigat 110mg Capsule

Dabigat 110mg capsule causes some side effects like all medications, although not everyone will experience them. 

Serious:

  • Severe allergic reactions, including rash, itching, swelling, severe dizziness, or difficulty breathing
  • Severe bleeding
  • Liver problems
  • Stroke or embolism

Common:

  • Upset stomach or indigestion
  • Heartburn
  • Nausea
  • Diarrhea
  • Mild bleeding, such as nosebleeds or bleeding gums
  • Bruising more easily than usual

Word of Advice

Advice regarding Dabigat 110mg capsule is to always consult with a healthcare professional before starting or making any changes to your medication regimen. They can assess your medical history, evaluate potential risks and benefits, provide personalized guidance, and monitor your progress throughout treatment. Additionally, closely follow the instructions and recommendations your healthcare provider gives, promptly report any unusual or concerning symptoms, and communicate openly about any concerns or questions you may have. 

Precautions should be taken when using this medication in patients with liver or kidney impairment, as dosage adjustments or special monitoring may be required. Be vigilant for any signs of bleeding, such as unusual bruising, nosebleeds, or blood in urine or stools, and promptly inform your healthcare provider if you experience any of these symptoms. Avoid discontinuing the medication without medical advice, as sudden cessation may increase the risk of stroke. Before any medical procedures or surgeries, inform all healthcare providers about your use. Pregnant and breastfeeding individuals should consult with healthcare professionals before using this medication. Your healthcare professional is the best resource for ensuring safe and effective medication use.


FAQs

Q 1. Do I need to have regular blood tests while on Dabigat 110mg capsule?

Unlike warfarin, Dabigat 110mg capsule does not require routine blood monitoring. However, your healthcare provider may perform periodic blood tests to assess kidney function or in specific situations

Q 2. What should I do if I miss a dose of Dabigat 110mg capsule?

If you miss a dose, take it as soon as you remember. However, if it's close to the next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take double doses to make up for the missed one.

Q 3. Can Dabigat 110mg capsule be used in patients with liver problems?

Dabigat 110mg capsule is generally safe for patients with mild to moderate liver impairment. However, caution is advised in severe liver impairment, as there is limited clinical experience in this population.

Q 4. Do I need to have regular blood tests while on Dabigat 110mg capsule?

Unlike warfarin, Dabigat 110mg capsule does not require routine blood monitoring. However, your healthcare provider may perform periodic blood tests to assess kidney function or in specific situations.

Q 5. Can Dabigat 110mg capsule be used in children or adolescents?

Dabigat 110mg capsule is primarily approved for adults and is not typically used in children or adolescents. Its safety and efficacy in pediatric populations have not been well-established.


Fact Box of Dabigat 110mg Capsule

Molecule name: Dabigatran etexilate

Therapeutic class: Anticoagulants

Pharmacological class: Direct thrombin inhibitors

Indications: Prevention and treatment of blood clots

References

  1. Spinler Sarah; The pharmacology and therapeutic use of Dabigat 110mg capsule; Journal of Clinical Pharmacology 2013; [Accessed on 24th July 2023], https://pubmed.ncbi.nlm.nih.gov/23400738/
  2. KP Garnock Jones; Dabigatran etexilate: A review of its use in the prevention of stroke and systemic embolism in patients with atrial fibrillation; American Journal of Cardiovascular Drugs: drugs, devices and other inventions 2011; [Accessed on 24th July 2023], https://pubmed.ncbi.nlm.nih.gov/21265583/
  3. Boehringer Ingelheim Ltd; Electronic Medicines Compendium; [Revised: May 2020] [Accessed on 24th July 2023], https://www.medicines.org.uk/emc/files/pil.4703.pdf
  4. Boehringer Ingelheim Pharmaceuticals, Inc, US Food and Drug Administration, [Revised on Nov 2011], [Accessed on 24th July 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/022512s007lbl.pdf

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