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DACOPLICE 15MG TABLET
Salt Composition : Dacomitinib
Manufacturer : PFIZER LTD
Origin of Medicine : United States of America
30 Tablet(s) In A Bottle
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Introduction to Dacoplice 15mg Tablet
Dacoplice 15mg tablet contains the active substance Dacomitinib. It is an antineoplastic drug that belongs to the class tyrosine kinase inhibitor. It is used as a first-line treatment in adults with a type of lung cancer called non-small cell lung cancer which has spread to other parts of the body, and if a test has shown that your cancer has certain changes in a gene called EGFR (epidermal growth factor receptor).
Do not take Dacoplice 15mg tabletif you are allergic to dacomitinib or any other ingredients of this medicine. Before initiating the treatment, inform your physician if you have any other lung problems because some lung problems may get worse during treatment with this medicine. Report to your doctor immediately if you develop diarrhea, skin rash, or symptoms of jaundice, including yellowing of your skin and eyes, dark or brown urine, and light-colored bowel movements.
Dacoplice 15mg Tablet is not indicated in children or adolescents under the age of 18 years. Inform your physician if you have any heart disease, liver disorder, or kidney problems before initiating the treatment. The most common side effects are skin rash, changes in nails, inflamed sore mouth, decreased appetite, dry skin, decreased weight, hair loss, cough, and severe itching of the skin. This medicine is not recommended for pregnant and breastfeeding women.
Uses of Dacoplice 15mg Tablet
- Metastatic non-small cell lung cancer with positive EGFR
Therapeutic Effects of Dacoplice 15mg Tablet
Dacoplice 15mg Tablet is a protein-tyrosine kinase inhibitor that blocks a specific abnormal protein created by a chromosomal abnormality that signals cancer cells to multiply. It inhibits the multiplication and induces cell death in abnormal cancer cells.
Interaction of Dacoplice 15mg Tablet with other drugs
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional and vitamin supplements, and herbal products. Certain medications may interact with the effects of Dacoplice 15mg Tablet and reduce its effectiveness by causing undesirable side effects. Inform your physician, especially if you are using medicines for any heart disease or psychiatric illness.
More Information about Dacoplice 15mg Tablet
- Store Dacoplice 15mg Tablet at room temperature ( 20 °C to 25 °C)
- keep the injection away from the reach of children and pets.
- If you forgot to take a dose, take it as soon as you remember. however, skip the missed dose if it is nearly time for the next dose.
- Do not take a double dose to make up a forgotten dose.
- Avoid direct contact with crushed tablets with the skin or mucous membrane. If such contact occurs, wash thoroughly.
How to consume Dacoplice 15mg Tablet
Your doctor will decide the dose and duration of the treatment based on your disease condition, severity, and other factors. Take the tablets as prescribed by your doctor. Do not break, crush, or chew the tablets. Swallow the tablet whole with a glass of water. Take this medicine with a meal to avoid stomach problems. Take the tablet at about the same time each day.
Safety Advices for Dacoplice 15mg Tablet
Dacoplice 15mg Tablet is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. An effective birth control method is necessary during the treatment and for 17 days after your last dose.
Breastfeeding is not recommended in patients taking Dacoplice 15mg Tablet because the medicine passes into the breast milk in small amounts and may harm your baby.
It is unknown whether Dacoplice 15mg Tablet can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.
Dacoplice 15mg Tablet is safe when administered in patients with liver diseases. No dose adjustments are necessary for mild, moderate or severe liver failure. Inform your physician if you have liver problems before initiating the therapy.
It is not known whether it is safe to consume alcohol with Dacoplice 15mg Tablet. Please consult your doctor.
Driving or operating heavy machinery is unsafe after taking Dacoplice 15mg Tablet because you may feel dizzy, drowsy, or have eye irritation.
Side Effects of Dacoplice 15mg Tablet
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
- Hair fall
- Inflammation in the nails
- Itchy skin
- Dry skin
- Decreased weight
- Decreased appetite
- Inflamed and sore mouth
- Severe itchy skin
- Respiratory illness
Word of Advice
This medicine contains lactose. If you have been diagnosed with an intolerance to some sugars, contact your doctor before taking this medicine. Your doctor will regularly do lab tests to check whether the medicine is working. Do not breastfeed during the treatment with this medicine and for 17 days after your last dose. This medicine makes your skin more sensitive to sunlight; wear sunscreen after consulting your doctor. Wear protective clothing before going outdoors.
Q 1. How to use Dacoplice 15mg Tablet?
Dacoplice 15mg Tablet is administered orally in the form of a tablet. The dose depends on several factors, including the condition being treated, the patient's weight, the particular regimen being used, and the patient's overall health. It should be taken with food and a large glass of water to minimize gastrointestinal irritation.
Q 2. Since I started using Dacoplice 15mg Tablet, I have noticed rashes and severe itching when I have sun exposure. Is it because of the medicine or the disease?
This medicine may make your skin much more sensitive to sunlight than it normally is. Exposure to sunlight may cause skin rash, itching, redness, or severe sunburn. When you are outdoors, wear protective clothing and use sunscreen with an SPF. Consult your doctor before taking necessary precautions.
Q 3. Can Dacoplice 15mg Tablet cause kidney damage?
Yes, when taken for a longer period the medicine may cause damage to your kidneys. Your doctors may recommend you take a routine blood tests to assess your kidney function.
Q 4. When is the best time to take Dacoplice 15mg Tablet?
Take the tablet as prescribed by your doctor. Take Dacoplice 15mg Tablet at the same time every day. It is usually taken with a meal and a large glass of water to avoid stomach problems.
Q 5. Does Dacoplice 15mg Tablet affect memory?
Memory impairments have been only reported in limited studies. Consult your doctor immediately if you have any trouble concentrating.
Fact Box of Dacoplice 15mg Tablet
Molecule name: Dacomitinib
Therapeutic class: Antineoplastics
Pharmacological class: Tyrosine kinase inhibitor
Indications: Non-small cell lung cancer
- HIGHLIGHTS OF PRESCRIBING INFORMATION. [Revised on 2018] [cited 2023 Mar 23]. Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/211288s000lbl.pdf
- Vizimpro 45 mg film-coated tablets - Summary of Product Characteristics (SmPC) - (emc). www.medicines.org.uk. [Revised on 2021] [cited 2023 Mar 23]. Available from: https://www.medicines.org.uk/emc/product/10356/smpc
- Sally CM Lau et al; Dacomitinib in the Management of Advanced Non-Small-Cell Lung Cancer; Drugs; Published on June 2019; Accessed on 02/12/2021; https://pubmed.ncbi.nlm.nih.gov/31069718/
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