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Darzalex 400mg Injection
Prescription Required
Salt Composition : Daratumumab
Manufacturer : JOHNSON & JOHNSON PVT LTD
Origin of Medicine : United States of America
1 Vial(s) Of 20ml
Introduction to Darzalex 400mg Injection
Darzalex 400mg injection is a targeted therapy for cancer containing the active ingredient Daratumumab, which belongs to the group of medicine called monoclonal antibodies. Monoclonal antibodies are proteins that recognize and attach to the specific target, killing the cancer cells. It is used to treat a type of cancer called multiple myeloma (bone marrow cancer) in adults 18 years or older. Report to your doctor if you have ever had a hepatitis B infection; this medicine may cause the hepatitis B virus to become active again. This medicine can decrease platelets (helps in blood clotting) and white blood cell counts (helps fight infections).Â
Do not take a Darzalex 400mg injection if you are allergic to Daratumumab or other medicine ingredients. This medicine is not recommended for children and adolescents. Inform your doctor if you get any infusion-related reactions, such as swollen face, lips, mouth, tongue, or throat. If you notice any infusion reactions, you need other medicine, or the infusion will be slowed down or stopped.Â
Consult your doctor if you are on a salt-controlled diet, as this medicine contains sodium. Tell your physician if you have a history of breathing problems (asthma or chronic obstructive pulmonary disease) or had shingles before taking Darzalex 400mg. This medicine can change the results of blood tests to match your blood type. You must tell your healthcare provider you are being treated with this medicine before receiving blood transfusions. Inform your doctor if you are pregnant or planning to get pregnant. Use effective contraception during and after the treatment for three months.
Uses of Darzalex 400mg Injection
Treatment of Multiple myeloma
Therapeutic Effects of Darzalex 400mg Injection
Darzalex 400mg binds specifically to a protein called CD38 found on the surface of multiple myeloma cells. This binding can trigger the immune system to attack and kill the cancer cells.
Interaction of Darzalex 400mg Injection with other drugs
Inform your healthcare provider about all the medicines you take, including prescription, over-the-counter, nutritional, supplements, and herbal products. In particular, tell your doctor if you are taking medicines for blood pressure or other heart conditions. Certain medications may interact with Darzalex 400mg and reduce its effectiveness by causing undesirable side effects.Â
More Information about Darzalex 400mg Injection
- Store Darzalex 400mg in the refrigerator (2°C to 8°C)
- Do not freeze
- keep the injection away from the reach of children and pets.
- If you have missed any dosing appointments, inform your doctor and schedule immediately.
How to consume Darzalex 400mg Injection
A trained doctor or nurse should only administer Darzalex 400mg. Do not self-administer the injection. Your doctor will decide the dose and duration of your treatment based on the disease severity and other factors. It will be given as an intravenous infusion, and you will be monitored carefully for unwanted side effects.Â
Safety Advices for Darzalex 400mg Injection
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Pregnancy
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Your doctor will prescribe Darzalex 400mg only if needed, as this medicine might cause harm to the unborn baby. So notify your doctor before starting the preganat if you are preganat or planning to get pregnant. Use effective contraception during and after the treatment for three months.Â
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Breast Feeding
 ÂIt is unknown whether Darzalex 400mg is safe to administer in breastfeeding patients. Before starting the treatment, notify your doctor if you are breastfeeding.Â
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Lungs
  It is unknown whether Darzalex 400mg is safe for patients with lung problems. Inform your physician if you have any lung disease before starting the treatment. Contact your doctor if you experience any lung-related symptoms, such as difficulty breathing.Â
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Liver
  It is unknown whether Darzalex 400mg is safe for patients with liver-related problems. Inform your physician if you have any liver disease before starting the treatment. Contact your doctor if you experience any liver-related symptoms.
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Alcohol
 ÂIt is unknown whether it is safe to consume alcohol with Darzalex 400mg as this medicine makes you feel drowsy. Please consult your doctor for more information.
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Driving
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It is unsafe to drive while taking Darzalex 400mg because this medicine might cause minor influence, so avoid driving and operating machinery during this treatment.
Side Effects of Darzalex 400mg Injection
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.
Serious
- Infusion reactions (itching, wheezing, chills, fever, throat tightness, runny nose, headache, low pressure)
- Changes in blood tests
- Decrease in blood cell counts
Common
- Nausea, vomiting
- Back pain, muscle spasms
- Diarrhea
- Tiredness
- Shortness of breath
- Upper respiratory tract infection
- Tingling, numbness, or pain
- Constipation
- Trouble sleeping
- Dizziness
- Joint pain
Word of Advice
If you experience any symptoms mentioned above, consult your doctor immediately. While undergoing treatment, use effective contraception and continue it for three months after stopping treatment. Darzalex 400mg is not recommended for children and adolescents under 18 years. Do not freeze the medicine. Before starting the treatment, inform your doctor about every underlying medical condition. Talk to your physician if you are on a salt-controlled diet, as this medicine contains sodium.
FAQs
Q 1. Is Darzalex 400mg chemotherapy medicine?
No, It is not a type of chemotherapy. Darzalex 400mg is a monoclonal antibody, a type of immunotherapy medication that works by stimulating the body's immune system to attack cancer cells.
Q 2. How often should I need to receive Darzalex 400mg treatments?
The frequency of Darzalex 400mg treatments can vary depending on the type and stage of the cancer being treated and other factors, such as the patient's overall health.
Q 3. Does Darzalex 400mg cure cancer?
Darzalex 400mg is not a cure for cancer. Instead, it can help to slow down or restrict the growth and spread of cancer cells, improving the quality of patients with certain types of cancer.
Q 4. Do I need to maintain any diet during the treatment with Darzalex 400mg?
No, you dont need to maintain any diet. Instead, inform your doctor if you are on a salt-controlled diet, as Darzalex 400mg contains sodium.
Q 5. I had a history of hepatitis B virus. Should I inform it before taking the Darzalex 400mg?
Yes, informing the past with HBV and every underlying medical condition before starting the treatment is mandatory.
Fact Box of Darzalex 400mg Injection
Molecule name: Daratumumab | Therapeutic class: Antineoplastics |
Pharmacological class: Monoclonal antibody | Indications: Treatment of multiple myeloma |
References
- Janssen-Cilag International NV, Electronic medicines compendium (EMC), [ Revised on Feb 2023] [ Accessed on 1 May 2023], https://www.medicines.org.uk/emc/files/pil.7250.pdf
- Janssen Biotech, Inc, US Food and Drug Administration, [ Revised on May 2018] [ Accessed on 1 May 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/761036s013lbl.pdf
- Danai Dima et al.; Evaluating Daratumumab in the Treatment of Multiple Myeloma: Safety, Efficacy, and Place in Therapy; Cancer Management and Research; Published on 26/08/2020; Accessed on 1 May 2023; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457558/
Disclaimer
MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.
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