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Fenoxene 50mg Injection
Prescription Required
Salt Composition : Phenoxybenzamine
Manufacturer : SAMARTH LIFE SCIENCES PVT LTD
Origin of Medicine : India
1 Vial(s) Of 1ml
Introduction to Fenoxene 50mg Injection
Fenoxene 50mg injection contains active components such as Phenoxybenzamine. It is a medication primarily used to treat pheochromocytoma, a rare tumor that typically develops in the adrenal glands. This helps to lower blood pressure, which is a critical factor in managing the symptoms of pheochromocytoma. This medication relieves the symptoms of this tumor, such as severe hypertension, rapid heart rate, sweating, headache, and anxiety. In cases where surgical removal of the tumor is not immediately possible, or if it is metastatic, it can be used for long-term management. The decision to use this medication should be made in consultation with a healthcare professional.
If an individual has hypersensitivity to Fenoxene 50mg injection or its components, the medication should not be used. Before starting this medication, it is important to inform the healthcare provider about any known allergies or hypersensitivities. Individuals with severe coronary artery disease or a history of heart attacks should not take this medication. It should not be taken in patients with peptic ulcer disease as it could aggravate peptic ulcers or other gastrointestinal conditions. It is generally not recommended for use in children due to limited study. Older patients may be more sensitive to the effects of Fenoxene 50mg injection, such as postural hypotension and dizziness, so it is necessary to consult a healthcare provider.
Uses of Fenoxene 50mg Injection
Fenoxene 50mg injection is used in the following:
- Pheochromocytoma treatment
- Alpha-blocker therapy
Therapeutic Effects of Fenoxene 50mg Injection
Fenoxene 50mg injection works through non-selective alpha-adrenergic receptor blockade, inhibiting the action of neurotransmitters like norepinephrine on smooth muscle cells lining blood vessels, which leads to vasodilation, reduced vascular resistance, and consequent blood pressure reduction.
Interaction of Fenoxene 50mg Injection with other drugs
Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Fenoxene 50mg injection, reducing effectiveness by causing undesirable side effects.Â
More Information about Fenoxene 50mg Injection
- Stored at room temperature from 20°C to 25°C.
- Keep away from moisture, heat, and light.
- It should not be frozen.
- Keep away from children and pets.
How to consume Fenoxene 50mg Injection
Fenoxene 50mg injection given by healthcare provider in a hospital setting. The specific dosage and administration instructions are provided by a healthcare professional based on the individual's condition and needs.
Safety Advices for Fenoxene 50mg Injection
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Pregnancy
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Fenoxene 50mg injection's safety during pregnancy has not been well studied. If you are pregnant or planning to become pregnant, consult your doctor before using this medication.
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Breast Feeding
 ÂFenoxene 50mg injection's effects on nursing infants are not clear. Consult a doctor if you are a breastfeeding woman before taking this medication.
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Lungs
  If you have any lung conditions, consult a doctor before starting Fenoxene 50mg injection.
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Liver
  If you have a history of liver conditions, it's important to consult your doctor before receiving Fenoxene 50mg injection.Â
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Alcohol
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Excessive alcohol can increase the risk of dizziness and fainting. It is not safe to take Fenoxene 50mg injection with alcoholÂ
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Driving
  Fenoxene 50mg injection can cause dizziness, particularly during the initial stages of treatment.
Side Effects of Fenoxene 50mg Injection
Fenoxene 50mg injection can cause some side effects. But not every individual who takes this medication will experience them
Serious
- Bleeding
- Thrombocytopenia
- Allergic Reactions
- Thrombosis
Common
- Bleeding at injection site
- Nausea
- Fever
- Headache
- Low blood pressure
Word of Advice
Inform your healthcare provider about your complete medical history, including any heart conditions, liver problems, kidney issues, lung disorders, and a history of low blood pressure before taking Fenoxene 50mg injection . Regularly monitor your blood pressure as directed by your healthcare provider. Be cautious when changing positions, especially from lying down to standing up, to avoid sudden drops in blood pressure and dizziness. Watch for signs of fluid retention, such as leg swelling or sudden weight gain, and inform your doctor if you notice any unusual changes. If you are scheduled for surgery, including dental procedures, inform your healthcare provider that you are taking this medication. Discuss dietary recommendations with your healthcare provider, especially regarding salt intake, as changes in blood pressure regulation could impact your dietary requirements. Be vigilant for signs of allergic reactions, such as rash, itching, swelling, or difficulty breathing.Â
FAQs
Q 1. Can I suddenly stop taking Fenoxene 50mg injection?
No, do not stop taking Fenoxene 50mg injection suddenly without consulting your healthcare provider. Stopping abruptly can lead to rebound high blood pressure.
Q 2. Can Fenoxene 50mg injection be used for conditions other than pheochromocytoma?
Fenoxene 50mg injection's primary use is for managing symptoms related to pheochromocytoma. Its use for other conditions is limited due to its non-selective alpha-blocking effects.
Q 3. How long does it take for Fenoxene 50mg injection to start working?
The onset of action can vary, but some symptom relief might be noticed shortly after starting treatment. However, it can take several days or weeks to achieve the full therapeutic effects.
Q 4. What should I do if I miss a dose of Fenoxene 50mg injection?
If you miss a dose, take it as soon as you remember. However, if it's close to the time for the next dose, skip the missed dose and resume your regular dosing schedule. Do not double up on doses.
Q 5. Can Fenoxene 50mg injection cause weight gain?
Some individuals may experience mild fluid retention while taking Fenoxene 50mg injection, which can lead to weight gain. Report any significant changes in weight to your healthcare provider.
Q 6. Are there any long-term side effects of Fenoxene 50mg injection?
Long-term effects can vary. Your healthcare provider will monitor your condition and assess whether the benefits of continued treatment outweigh any potential risks.
Fact Box of Fenoxene 50mg Injection
Molecule name:Â Â Phenoxybenzamine | Therapeutic class: Antihypertensive, Alpha-Adrenergic |
Pharmacological class: Non-Selective Alpha-Adrenergic Antagonist | Indications:  1. Pheochromocytoma treatment 2. Alpha-blocker therapy |
References
- Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Adrenergic agonists and antagonists, 12th edition, 2011, 309.
- KD Tripathi, Essentials of Medical Pharmacology, Antiadrenergic drugs and drugs for glaucoma, 7th edition, 2013, 141.
- ADVANZ Pharma, Electronic medicines compendium (emc), [Revised on 30th Aug 2022] [ Accessed on 24th August 2023], https://www.medicines.org.uk/emc/medicine/25189/PIL/Phenoxybenzamine#gref
- WellSpring Pharmaceutical Corporation, US Food and Drug Administration, [Revised on March 2008] [ Accessed on 24th August 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/008708s025lbl.pdf
Disclaimer
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