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Fibrogen-I Injection
Last updated on 31 Mar 2026 | 09:31 AM (IST)
₹13156
MRP: ₹16445
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Fibrogen-I Injection
Salt Composition
FIBRINOGENMarketer
INTAS PHARMACEUTICALS LTD
Prepaid Only. Non-Returnable.
20% OFF
₹13156
MRP: ₹16,445.00
Inclusive of all taxes
20% Off
Salt Composition
FIBRINOGENMarketer
INTAS PHARMACEUTICALS LTD
Prepaid Only. Non-Returnable.
Dispatch: Today
Care delivered without the wait. Your order is prioritized for rapid dispatch to ensure it reaches your doorstep on time.
Substitutes
Fibrinorel 1gm Injection
RELIANCE LIFE S...
₹ 12500.00/injection
4% cheaper
Introduction
Fibrinogen-I Injection contains an active component called human fibrinogen. It is mainly used to treat bleeding episodes in people with a congenital fibrinogen deficiency, which may result from genetic mutations or liver disease. This medicine is also used as an adjunct to hemostasis (blood clotting) in adults undergoing surgery when standard surgical techniques are not enough to control bleeding. It helps stop bleeding and prevent further blood loss in cases of massive hemorrhage. Doctors may also recommend this injection to women who are at risk of premature delivery to help manage bleeding risks. Additionally, it is useful for patients with acquired fibrinogen deficiency caused by conditions such as liver disease, disseminated intravascular coagulation (DIC), afibrinogenemia, hypofibrinogenemia, or other disorders that damage the liver or interfere with fibrinogen production.
Many patients look for information about the Fibrogen-I Injection price and the Fibrogen-I Injection composition, which contains human fibrinogen as the main active ingredient. The exact Fibrogen-I Injection dosage is determined by your doctor based on your health condition, bleeding severity, and individual response to treatment. If you are wondering where to buy Fibrogen-I Injection in India, it is usually available in major hospitals, specialized pharmacies, or can be ordered through trusted online medical suppliers.
When is Fibrogen-I Injection given? It is generally administered during active bleeding episodes, before or during surgery when there is a risk of severe blood loss, in massive hemorrhage cases, and in conditions like congenital or acquired fibrinogen deficiency to help restore normal clotting ability.
Uses
Fibrinogen-I Injection is used in the following:
- Fibrinogen replacement therapy for bleeding disorders
- Coagulation management in liver diseases
- Disseminated intravascular coagulation (DIC)
- Afibrinogenmia
- Hypofibrinogenemia
How Fibrogen-I Injection works
Fibrinogen-I Injection molecules are converted into fibrin by the enzyme thrombin. Fibrin strands form a meshwork, trapping blood cells and creating a stable blood clot at the site of injury or bleeding. This clot helps to staunch bleeding and promote wound healing. The missing Fibrinogen-I Injection enhances the body's ability to form these essential blood clots, preventing excessive bleeding in individuals with Fibrinogen-I Injection deficiency disorders.
Interaction of Fibrogen-I Injection with other drugs
Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Fibrinogen-I Injection, reducing effectiveness by causing undesirable side effects.
Storage conditions
- Stored at room temperature from 2°C to 8°C.
- Keep away from moisture, heat, and light.
- It should not be frozen.
- Keep away from children and pets.
How to use Fibrogen-I Injection
Fibrinogen-I Injection can be administered through several routes, including intravenous (IV), intramuscular (IM), and, in some cases, intraarterial (IA). The healthcare provider determines the choice of administration route based on the patient's needs and the urgency of treatment.
Safety Advice for Fibrogen-I Injection
Breast Feeding
Fibrinogen-I Injection concentrate is generally safe to take while breastfeeding. However, talking to your doctor before taking any breastfeeding medication is important.
Alcohol
It is not safe to take Fibrinogen-I Injection with alcohol. Alcohol can interfere with how Fibrinogen-I Injection works and increase the risk of bleeding.
Liver
If you have liver conditions, consult a healthcare provider before using Fibrinogen-I Injection.
Lungs
Before using Fibrinogen-I Injection in individuals with lung conditions, consult with a healthcare provider if you have lung conditions.
Driving
If you have Fibrinogen-I Injection deficiency and you need to drive, it is important to talk to your doctor. Your doctor may recommend that you take it before driving.
Pregnancy
There is not enough information about the safety of fibrinogen-I injection concentrates in pregnant women. So consult your doctor before using it.
Side Effects
Fibrinogen-I Injection causes some side effects like all medications, although not everyone will experience them.
Serious
- Allergic Reactions
- Transfusion-related acute lung injury (TRALI)
- Transfusion-associated circulatory overload (TACO)
- Transfusion-transmitted infections
- Thrombosis
- Fluid overload
Common
- Fever
- Chills
- Flushing
- Nausea
- Headache
- Mild allergic reactions (itching, hives)
Expert Tips
-
Assess patients for allergies and potential allergic reactions before using Fibrinogen-I Injection.
-
Review underlying medical conditions such as cardiovascular, liver, or kidney diseases, as these can impact treatment safety and effectiveness.
-
Consider possible medication interactions, especially with anticoagulants or antiplatelet drugs, and adjust dosages if needed.
-
Monitor patients with thrombocytopenia, kidney dysfunction, or those receiving multiple transfusions, as these factors can affect treatment response.
-
Inform patients receiving Fibrinogen-I Injection derived from human plasma about the minimal risk of viral transmission.
FAQs about Fibrogen-I Injection
Q1.
Is Fibrinogen-I Injection therapy a lifelong treatment for congenital Fibrinogen-I Injection deficiency?
For individuals with congenital fibrinogen deficiency, fibrinogen-I injection therapy is often required throughout their lifetime to prevent bleeding episodes. The treatment plan is tailored to the patient's specific needs.
Q2.
Can Fibrinogen-I Injection therapy cause blood clots (thrombosis)?
While Fibrinogen-I Injection therapy promotes clot formation, it must be administered carefully to avoid excessive clotting (thrombosis). Patients at risk of thrombosis or with a history of clotting disorders should be monitored during treatment.
Q3.
Is it safe to receive too much Fibrinogen-I Injection?
Yes, excessive fibrinogen-I injection therapy can lead to an increased risk of thrombosis (clot formation). Healthcare providers closely monitor fibrinogen levels during treatment to ensure they remain within the desired range.
Q4.
Can Fibrinogen-I Injection be used in rare bleeding disorders other than fibrinogen deficiency?
Fibrinogen-I Injection may be considered in rare bleeding disorders characterized by dysfunction in fibrinogen function or in cases of acquired fibrinogen deficiencies due to underlying medical conditions.
Q5.
Is it safe to resume Fibrinogen-I Injection after experiencing side effects?
Whether to continue Fibrinogen-I Injection after experiencing side effects should be carefully evaluated by healthcare providers. In some cases, therapy may be resumed with precautions, while alternative treatments may be considered in others.
Fact Box of Fibrogen-I Injection
|
Molecule name |
Fibrinogen |
|
Therapeutic class |
Coagulation Factor Replacement |
|
Pharmacological class |
Hemostatic Agent |
|
Indications |
1. Fibrinogen-I Injection replacement therapy for bleeding disorders 2. Coagulation management in liver diseases 3. Disseminated intravascular coagulation (DIC) 4. AFibrinogen-I Injectionemia 5. HypoFibrinogen-I Injectionemia |
References
- KD Tripathi, Essentials of Medical Pharmacology, Drugs affecting coagulation, Bleeding and Thrombosis, 7th edition, 2013, 616.
- Grifols UK Ltd, Electronic medicines compendium (EMC), [Revised on 4th August 2023] [Accessed on 8th September 2023], https://www.medicines.org.uk/emc/files/pil.5909.pdf
- Octapharma USA Inc, US Food and Drug Administration, [Revised on Dec 2020] [Accessed on 8th September 2023], https://www.fda.gov/media/105864/download
Disclaimer
MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.
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Author Details
Written By
Dr. Archana Gupta
BDS
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 31 Mar 2026 | 09:31 AM (IST)
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