GAZYVA 1000MG INJECTION
OBINUTUZUMAB
Manufacturer : ROCHE PRODUCTS INDIA PVT LTDOrigin of Medicine : SwitzerlandContact us for latest updates.
Contact us for latest updates.
Introduction:
Gazyva 1000mg Injection contains Obinutuzumab. It is used to treat two kinds of cancer, namely chronic lymphocytic leukemia (CLL) and follicular lymphoma (FL). In both CLL and FL, the white blood cells called lymphocytes multiply in an uncontrolled and abnormal manner. In CLL, the cancer cells occur in the blood and bone marrow. In FL, the cancer cells occur in lymph node sites in the body as well as in the bone marrow.
Talk to your physician if you have any infections, heart problems, brain problems, lung disorders, liver disorders, or taking medicines for high blood pressure or blood clots. You need to inform your physician if you have ever taken medicines that affect your immune system (immunosuppressants or chemotherapy) or if you are about to have any vaccination before taking Gazyva 1000mg Injection.
This medication is not recommended for adolescents and children under the age of 18. Use effective birth control during the treatment and for at least 18 months after the last dose. The most common side effects of Gazyva 1000mg Injection are headache, nausea, diarrhea, and alterations in blood pressure and heartbeat.
Uses of Gazyva 1000mg Injection:
- Chronic lymphocytic leukemia (CLL)
- Follicular lymphoma (FL)
How Gazyva 1000mg Injection works:
Gazyva 1000mg Injection binds to the target on the surface of the affected cells (B-lymphocytes) and and inhibits the growth of cancer cells.
Interactions with other drugs:
Inform your doctor about any medications you are taking or have taken before the treatment.
More information:
- Keep Gazyva 1000mg Injection out of sight and reach of children.
- Store in a refrigerator (2°C to 8°C).
References:
- Roche Products Limited, Electronic medicines compendium (emc), [Revised on Jan 2021] [ Accessed on 11th August 2021], https://www.medicines.org.uk/emc/files/pil.3279.pdf
- Genentech, Inc, US Food and Drug Administration, [Revised on Nov 2017] [ Accessed on 9th August 2021], https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/125486s017s018lbl.pdf
- Jenny O’Nions, William Townsend et al; The role of obinutuzumab in the management of follicular lymphoma; Future Oncology; Published on Nov 2019; Accessed on 11/08/2021; https://pubmed.ncbi.nlm.nih.gov/31538821/
How to use Gazyva 1000mg Injection:
It will be given to you by your health care professional.
Safety advice:
Pregnancy:
Gazyva 1000mg Injection may cause harm to the unborn baby. You need to tell your physician if you are pregnant or planning to get pregnant before taking this medication.
Breastfeeding:
You must not breastfeed your baby during treatment with Gazyva 1000mg Injection or for 18 months after stopping the treatment. You need to tell your physician if you are breastfeeding before taking this medicine.
Liver:
You need to tell your physician if you have any liver disorders before taking Gazyva 1000mg Injection.
Driving:
Gazyva 1000mg Injection may cause dizziness. Avoid driving if you are unwell.
Others:
- Talk to your physician if you have brain problems, lung disorders, heart diseases, infections, or are about to have any vaccines before taking Gazyva 1000mg Injection.
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.
Serious:
- Infusion-related reactions (nausea, dizziness, diarrhea, headache, fever, high or low blood pressure, fast heartbeats, chest discomfort, vomiting, tiredness)
- Infections (sore throat, burning pain when passing urine, feeling weak, painful rash, cough, chest pain)
Common:
- Joint pain, muscle pain
- Constipation
- Hair loss, itchiness
- Low blood cell count
- Sleeplessness
- Depression
- Weight gain
- Runny or blocked nose
- Pain in mouth or throat
- Bone pain
- Heartburn
- Kidney problems

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