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Gestone 50mg Injection

Prescription Required

Salt Composition : Progesterone


Origin of Medicine : India

MRP: 72.7
Price :64
You Save :9 (12%)

10 Ampoule(s) Of 1ml

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Introduction to Gestone 50mg Injection

Gestone 50mg Injection contains the active component Progesterone. It is a hormone that plays a vital role in the female reproductive system and menstrual cycle. It is produced mainly by the ovaries after ovulation, but the placenta can also produce it during pregnancy and in smaller amounts by the adrenal glands. Gestone 50mg Injection is a synthetic form of Progesterone prescribed for various medical purposes. These medications are designed to mimic the natural effect. It is commonly used in hormone replacement therapy for menopausal women or to regulate the menstrual cycle in cases of irregular periods.

Individuals who have a known allergy or hypersensitivity to it or any of its components should avoid this medication. It may not be recommended for individuals with certain medical conditions, such as liver disease, certain types of cancer (e.g., breast cancer, liver cancer), a history of blood clotting disorders, or undiagnosed vaginal bleeding. These conditions can increase the risk of complications or may be exacerbated by Gestone 50mg Injection. In some cases, individuals with certain hormonal imbalances, such as uncontrolled hyperthyroidism or poorly managed diabetes, may need careful monitoring or adjustment of their medication regimen.

Uses of Gestone 50mg Injection

  • Hormone replacement therapy: Gestone 50mg Injection is used along with estrogen to reduce menopausal symptoms.
  • Amenorrhea: A condition in which women don’t get their periods for months
  • Reduce the risk of uterine cancer

Therapeutic Effects of Gestone 50mg Injection

The therapeutic effect of Gestone 50mg Injection is to regulate and support various reproductive processes in the body, including the menstrual cycle, fertility treatments, hormone replacement therapy, and pregnancy maintenance. It helps prepare the uterus for potential pregnancy, maintains the uterine lining, prevents contractions that could lead to miscarriage, and contributes to overall hormonal balance. It can also be used in contraception to inhibit ovulation, thicken cervical mucus, and create an unfavorable environment for sperm, thus preventing pregnancy.

Interaction of Gestone 50mg Injection with other drugs

Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Gestone 50mg Injection, reducing effectiveness by causing undesirable side effects. 

More Information about Gestone 50mg Injection

  • Stored at controlled room temperature, between 20°C to 25°C (68°F to 77°F).
  • Keep away from moisture, heat, and light.
  • It should not be frozen.
  • Keep away from children and pets.

How to consume Gestone 50mg Injection

This injection is given by a healthcare provider. The dosage and frequency will depend on the specific condition being treated. 

Safety Advices for Gestone 50mg Injection

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This medicine is safe for pregnancy if prescribed by your doctor. It does not cause any harm to developing fetus.

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Breast Feeding


Gestone 50mg Injection may not be recommended while breastfeeding, as it can pass into breast milk and potentially affect the nursing infant.

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If you have pre-existing lung conditions or respiratory issues, it's important to inform your healthcare provider before taking Gestone 50mg Injection.

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Gestone 50mg Injection is generally used cautiously in individuals with liver impairment or liver disease. The medication is metabolized in the liver, and impaired liver function can affect the metabolism and clearance of this medication from the body.

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Combining Gestone 50mg Injection with alcohol is generally not recommended. Alcohol can increase the sedative effects of this medication and may enhance certain side effects, such as drowsiness, dizziness, and impaired coordination.

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Gestone 50mg Injections can cause side effects that may impair your ability to drive or operate machinery safely. Common side effects are drowsiness, dizziness, and vision changes. These effects can affect your coordination, reaction time, and judgment, making driving unsafe or performing tasks requiring alertness.

Side Effects of Gestone 50mg Injection

Gestone 50mg Injection cause some side effects like all medications, although not everyone will experience them. 


  • Allergic reaction
  • Swelling
  • Painful urination
  • Vaginal bleeding
  • Depression
  • Memory loss
  • Breast lumps
  • Dark patches on skin
  • Vomiting
  • Blood clots


  • Nausea
  • Bloating
  • Vaginal discharge
  • Mood swings
  • Frequent urination
  • Tiredness

Word of Advice

It is important to inform your healthcare provider about any existing medical conditions, including liver or kidney impairment, epilepsy, or cardiovascular diseases. Some individuals may experience hypersensitivity reactions to Gestone 50mg Injection, including allergic reactions. Seek immediate medical attention if you develop symptoms such as rash, itching, swelling, or difficulty breathing. It should be used cautiously in individuals with a history of cardiovascular disease, arrhythmias, or those taking other medications that can affect heart rhythm. Pregnant or breastfeeding individuals should seek medical advice before using it.  Do not smoke while taking this medication, as this may increase your chances of a blood clot.


Q 1. Can Gestone 50mg Injection be used for male patients?

While Gestone 50mg Injection is primarily associated with female reproductive health, it may also have uses in certain male conditions. Your healthcare professional can provide more information on cases where this medication may be prescribed for male patients.

Q 2. Can Gestone 50mg Injection be used for non-reproductive health conditions?

While Gestone 50mg Injection is commonly used in reproductive health contexts, emerging studies explore its potential therapeutic applications in various non-reproductive conditions such as neuroprotection, mood disorders, and cardiovascular health. However, the use of this medication for non-reproductive conditions is still being researched, and its efficacy and safety may vary.

Q 3. Can Gestone 50mg Injection be used for contraception?

Gestone 50mg Injection can be used as a form of contraception. Discussing contraceptive options with your healthcare professional to determine the most suitable method for you is important.

Q 4. Can Gestone 50mg Injection be used for fertility treatment in menopausal women?

Gestone 50mg Injection is commonly used in fertility treatments, but its use in menopausal women for fertility purposes may vary. Depending on the specific circumstances and underlying causes of infertility, your healthcare professional can guide the potential role of this medication in your fertility treatment plan.

Q 5. Can Gestone 50mg Injection be used to prevent miscarriages?

Gestone 50mg Injection is often prescribed to support pregnancy and reduce the risk of miscarriage, particularly in cases of Progesterone deficiency or other factors impacting pregnancy viability. Your healthcare professional can evaluate your situation and determine if this medication is an appropriate intervention for preventing miscarriages.

Q 6. Can Gestone 50mg Injection affect mood and emotional well-being?

Gestone 50mg Injection, like any hormone therapy, can potentially impact mood and emotional well-being. While some individuals may experience mood changes or emotional fluctuations while using this medication, others may not. If you have concerns about the effects on your mood or emotional state, discussing them with your healthcare professional is important.

Q 7. What are the common side effects of Gestone 50mg Injection?

Common side effects of Gestone 50mg Injection may include fatigue, dizziness, headache, breast tenderness or swelling, bloating, nausea, mood changes, and changes in menstrual bleeding patterns. These side effects are typically mild and transient, and not everyone experiences them.

Fact Box of Gestone 50mg Injection

Molecule name: Progesterone

Therapeutic class: Progestins

Pharmacological class: Progestational agent



1. Gastroparesis

2. Nausea and vomiting

3. Gastroesophageal reflux disease (Acid reflux and heartburn)


  1. Watson Laboratories Inc, US Food and Drug Administration, [Revised on 2007] [Accessed on 12th June 2023],
  2. MP Warren et al., Use of Progesterone in clinical practice, Int J Fertil Womens Med, 1999, 44(2):96-103. [Accessed on 12th June 2023],
  3. Donald G Stein et al, The case for Progesterone, Ann N Y Acad Sci, 2005, 1052:152-69 [Accessed on 12th June 2023],
  4. Edwards M et al., Progestins, NCBI Bookshelf, [Revised on 2020] [Accessed on 12th June 2023],
  5. Besins Healthcare (UK) Ltd, Electronic Medicines Compendium (EMC) [Revised on 10 May 2022], [Accessed on 12th June 2023], 


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