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Granicip 1-DT Tablet
Last updated on 21 Aug 2026 | 06:44 AM (IST)
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Introduction to Granicip 1-DT Tablet
Granicip 1-DT tablet belongs to the group of medicines known as 5-HT3 receptor antagonists or antiemetics. It contains the active ingredient Granisetron. It is used to prevent and treat nausea, vomiting, or sickness caused by cancer treatments such as chemotherapy, radiotherapy, or after surgery. Nausea is characterized by stomach pain and the urge to vomit. The forcible voluntary or involuntary emptying of the stomach's contents through the mouth is known as vomiting.
The common side effects of Granicip 1-DT tablet are headaches, constipation, diarrhea, insomnia, and changes in liver function. These side effects do not appear in everyone and vary individually. Inform your physician if these side effects disturb or persist with you.
Report to your doctor if you have allergic reactions to Granicip 1-DT tablet and its ingredients. Inform your physician if you have any bowel movement problems or heart problems before starting treatment with a Granicip 1-DT tablet. Serotonin syndrome is a rare but serious complication that can arise when this medicine is taken with certain other medicines (such as duloxetine, fluvoxamine, etc.) Inform your doctor about your medications before starting treatment with a Granicip 1-DT tablet. It is suggested for pregnant and breastfeeding women.
Uses of Granicip 1-DT Tablet
Prevent or treat nausea and vomiting during cancer treatment.
Therapeutic Effects of Granicip 1-DT Tablet
Granicip 1-DT tablet works by blocking the action of serotonin (chemical messenger) in the brain, which is responsible for nausea and vomiting during cancer treatment like chemotherapy, radiation therapy, or after surgery.
Interaction of Granicip 1-DT Tablet with other drugs
Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional and vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications may interact with Granicip 1-DT tablet and cause undesirable side effects.
More Information about Granicip 1-DT Tablet
- Keep this medicine out of sight and reach of children.
- Do not use it after the expiration date.
How to consume Granicip 1-DT Tablet
Swallow the whole Granicip 1-DT tablet with a glass of water. Avoid chewing or breaking the tablet. Your physician will decide the dose and duration depending on the severity of your medical condition.
Safety Advice for Granicip 1-DT Tablet
Breast Feeding
Granicip 1-DT tablet is used with caution in breastfeeding women as it is unknown if it passes into breast milk. Consult with your physician for advice.
Alcohol
It is unknown whether it is safe to consume alcohol with Granicip 1-DT tablet. Consult your doctor for advice.
Liver
Inform your physician before starting this treatment if you have liver disease.
Lungs
Inform your physician before starting this treatment if you have lung diseases.
Driving
Granicip 1-DT tablet usually does not affect your ability to drive and operate heavy machines. Avoid driving or using machinery if you experience side effects.
Pregnancy
Granicip 1-DT tablet is not safe to be used during pregnancy. Consult with your doctor for advice.
Side Effects of Granicip 1-DT Tablet
Side effects are unwanted symptoms caused by medicines. Although all medicines cause side effects, not everyone gets them.
Serious
- Allergic reaction (anaphylaxis)
- Skin rashes
- Abnormal involuntary movements, such as shaking
- Muscle rigidity and contractions
- Changes in the heartbeat and ECG readings
Common
- Headache
- Constipation
- Diarrhea
- Insomnia (difficulty in sleeping)
- Changes in liver function tests
Word of Advice
Inform your healthcare provider while taking Granicip 1-DT tablet if you are undergoing any medical tests. It is advised to monitor your heart function with an ECG (electrocardiogram) since this medication may cause irregular heartbeat. It is not given to children to treat sickness after surgery. Eat high-fiber foods in your diet and drink more water to stay hydrated.
FAQs about Granicip 1-DT Tablet
Q1.
What is Granicip 1-DT tablet used for?
Granicip 1-DT tablet is used to prevent or treat nausea and vomiting during cancer treatment, like radiotherapy, chemotherapy, or after surgery.
Q2.
Does Granicip 1-DT tablet cause constipation?
Yes, Granicip 1-DT tablet can cause constipation, which is one of the side effects of this medication. You can avoid it by eating high-fiber foods in your diet.
Q3.
Can I drive after taking Granicip 1-DT tablet?
Yes, Granicip 1-DT tablet does not affect the ability to drive and operate heavy machines. If you experience any side effects, then avoid driving or operating any machine.
Q4.
What class of medication is Granicip 1-DT tablet?
Granicip 1-DT tablet belongs to the class of medications known as 5-HT3 receptor antagonists or antiemetics.
Q5.
Who is contraindicated to taking Granicip 1-DT tablet?
Patients who have experienced allergic reactions (hypersensitivity), bowel movement problems, heart problems, and pregnant and breastfeeding women should not use Granicip 1-DT tablet.
Fact Box of Granicip 1-DT Tablet
Molecule name: Granisetron | Therapeutic class: 5-HT3 receptor antagonists |
Pharmacological class: Anti emetics | Indications: 1. Prevent or treat nausea and vomiting during cancer treatment. |
References
1. Hameln Pharma, Electronic Medicines Compendium (EMC), [Revised on Apr 2020] [Accessed on 22 November 2022], https://www.medicines.org.uk/emc/files/pil.6423.pdf
2. Roche Laboratories Inc., US Food and Drug Administration, [ Revised on Sep 2009] [ Accessed on 22 November 2022], https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/20334s007s008lbl.pdf
3. GL Plosker et al; Granisetron: A review of its pharmacological properties and therapeutic use as an antiemetic; Published on 1991, Accessed on 22/09/2022, https://pubmed.ncbi.nlm.nih.gov/1723376/
4. Matti Apro; Granisetron: an update on its clinical use in the management of nausea and vomiting; Published on 2004, Accessed on 22/9/2022, https://pubmed.ncbi.nlm.nih.gov/15561811/
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Author Details
Written By
Dr. Bhairavi S
Pharm. D
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 21 Aug 2026 | 06:44 AM (IST)
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