• Reversible loss of consciousness (General anesthesia)

The action of hyprovan 200mg, like all general anesthetics, needs to be better understood. However, it is thought to produce loss of consciousness by potentiating the actions of certain brain chemicals (neurotransmitter GABA) through the specific receptors (ligand-gated GABA A receptors) and decreasing the flow of chloride ions across the nerve cells required to maintain alertness.

Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications may interact with hyprovan 200mg  injection and cause undesirable side effects, especially if you are taking the antibiotic rifampicin (for tuberculosis- TB).

• Store hyprovan 200mg below 25°C.
• Protect from light.
• Keep out of reach of children.

This medicine is given only in a hospital set up by a trained healthcare provider. It will be given to you as an injection into a vein, usually in the back of your hand or forearm. Your doctor will decide your most apt dosage based on age, body weight, and physical circumstances.  

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.

Serious

• Allergic reactions - symptoms of difficulty in breathing, swelling of the eyelids, face, or lips, rash or itching (especially affecting your whole body)
• Stress cardiomyopathy - symptoms of chest pain, shortness of breath, nausea, or an irregular heartbeat, especially if you are stressed.

Common

• Injection site pain
• Low blood pressure
• Changes in your breathing pattern
• Slow heartbeat
• Nausea and Vomiting
• Headache
• Withdrawal symptoms - unusual behavior, sweating, shaking, and feeling anxious (in children)
• Flushing of the skin (in children)

Please inform your doctor if you are on a sodium-controlled diet or have allergies to peanuts or soya, as hyprovan 200mg  injection contains these components. If the injection is administered over extended periods in intensive care, your doctor may prescribe a zinc supplement to prevent a decrease in your zinc levels. Before starting the treatment, it is essential to inform your doctor if you are allergic to any of these components or have any concerns.

It is essential to trust your medical team and communicate openly with them. Hyprovan 200mg  is a powerful anesthetic used to induce and maintain anesthesia, and while it is generally safe, it is crucial to disclose your complete medical history, allergies, and any medications you are taking to your healthcare provider. Follow their instructions diligently, and be sure to inform them about any unusual sensations or discomfort during the procedure. It is natural to feel apprehensive, but focusing on the expertise of your medical team and openly communicating your concerns with your doctor can help ensure a safer and more comfortable experience. 

1. Mercury Pharmaceuticals Ltd, Electronic medicines compendium (EMC), [Revised on April 2022], [Accessed on 27th Sept 2023], https://www.medicines.org.uk/emc/files/pil.5492.pdf
2. Fresenius Kabi USA, US Food and Drug Administration (FDA), [Revised on Aug 2022], [Accessed on 27th Sept 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2022/019627s069lbl.pdf
3. KD Tripathi, Essentials of Medical Pharmacology, Drugs acting on central nervous system, 2019, 409-410
4. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, General Anesthetics and Therapeutic Gases, 2018, 390-391