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Icikinase 1.5MIU Injection

Prescription Required

Salt Composition : Streptokinase

Manufacturer : ABBOTT

Origin of Medicine : India

MRP: 2225.09
Price :1350
You Save :875 (39%)

1 Vial(s)


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Introduction to Icikinase 1.5miu Injection

Icikinase 1.5MIU Injection contains an active component such as Streptokinase. It is a medication that is used for the treatment of blood clot-related conditions.It is used to treat deep vein thrombosis, a condition where blood clots form in the deep veins, usually in the legs.This medication is used to treat pulmonary embolism, which occurs when a blood clot travels to the lungs and blocks blood flow.  In certain cases, It is used to treat arterial blood clots, such as those that can cause ischemic strokes.  Icikinase 1.5MIU Injection is used to maintain the patency of dialysis fistulas or grafts, which are artificial connections between an artery and a vein used in patients with kidney failure who require dialysis.

Individuals with a known hypersensitivity or allergic reaction to Icikinase 1.5MIU Injection or any components of the medication should not take Icikinase 1.5MIU Injection. Do not take this medication in the presence of active internal bleeding, such as gastrointestinal bleeding or recent surgery. Patients with a history of hemorrhagic stroke should not take this medication. Do not take this medication if you are having severe kidney dysfunction. Old-age patients should always consult a healthcare provider because of the higher risk of bleeding due to age-related changes in blood vessels and other medical conditions. Icikinase 1.5MIU Injection is generally not recommended for use in children because there is limited study on its safety and efficacy in pediatric populations.


Uses of Icikinase 1.5miu Injection

Icikinase 1.5MIU Injection is used in the following:

  • Myocardial Infarction (heart attack)
  • Deep vein thrombosis (DVT)
  • Pulmonary embolism
  • Arterial clots
  • Peripheral arterial disease
  • Thrombosis in dialysis fistulas/grafts

Therapeutic Effects of Icikinase 1.5miu Injection

Icikinase 1.5MIU Injection operates as a thrombolytic agent by interacting with plasminogen, a precursor protein in the blood. Through its binding, It triggers plasminogen's conversion into plasmin, an active enzyme that dismantles fibrin, the structural framework of blood clots, leading to their dissolution. Promoting this clot breakdown restores blood flow by eliminating blockages in blood vessels, which is essential for preventing tissue damage and related complications.


Interaction of Icikinase 1.5miu Injection with other drugs

Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Icikinase 1.5MIU Injection, reducing effectiveness by causing undesirable side effects. 


More Information about Icikinase 1.5miu Injection

  • Store at room temperature, between  2°C to 8°C
  • Keep away from moisture, heat, and light.
  • It should not be frozen.
  • Keep away from children and pets.

How to consume Icikinase 1.5miu Injection

Icikinase 1.5MIU Injection is administered through the intravenous (IV) route or intracoronory. It may also be delivered through an arterial catheter for more localized treatment. Healthcare professionals perform administration following prescribed dosages and guidelines.


Safety Advices for Icikinase 1.5miu Injection

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Pregnancy

  

Icikinase 1.5MIU Injection is unsafe during pregnancy due to potential risks to the developing fetus.

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Breast Feeding

  

It is unknown whether Icikinase 1.5MIU Injection is excreted in human milk. Always consult a healthcare provider before taking this medication.

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Lungs

  

If you have preexisting lung conditions, informing your healthcare provider before starting Icikinase 1.5MIU Injection is advisable.

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Liver

  

Discuss your liver health with your healthcare provider before using Icikinase 1.5MIU Injection, as they can determine its suitability and monitor your liver function if necessary.

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Alcohol

  

If you are an alcoholic, always consult a healthcare provider before taking Icikinase 1.5MIU Injection.

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Driving

  

If you have any side effect that will impair your driving ability, consult a doctor before taking Icikinase 1.5MIU Injection.


Side Effects of Icikinase 1.5miu Injection

Icikinase 1.5MIU Injection causes some side effects like all medications, although not everyone will experience them. 

Serious

  • Bleeding
  • Allergic Reactions
  • Hypotension (Low Blood Pressure)
  • Fever and Chills

Common

  • Bleeding at Injection Site
  • Nausea and Vomiting
  • Fever
  • Allergic Skin Reactions
  • Minor Drop in Blood Pressure
  • Flushing

Word of Advice

Monitor for signs of allergic reactions, including rash, itching, swelling, and difficulty breathing. Discontinue Icikinase 1.5MIU Injection and seek medical attention immediately if any allergic symptoms occur. Use with caution in individuals with a history of bleeding disorders, recent surgery, ulcers, or other conditions that might increase bleeding risk. Monitor blood pressure during administration and address any hypotensive episodes. Follow the prescribed dosage as directed by your healthcare provider. Individuals with severe liver or kidney impairment should talk to healthcare providers to assess their condition and determine the appropriate course of action. Use this medication with caution in individuals who have recently undergone surgery, or had significant trauma.


FAQs

Q 1. Is Icikinase 1.5MIU Injection still commonly used today?

Icikinase 1.5MIU Injection usage has decreased over the years due to newer and safer thrombolytic agents available. Healthcare providers often opt for these alternatives.

Q 2. What should I do if I miss a dose of Icikinase 1.5MIU Injection?

Icikinase 1.5MIU Injection is usually administered by healthcare professionals in controlled settings, so missing a dose isn't applicable in the same way as oral medications. Follow your healthcare provider's instructions.

Q 3. How long does a Icikinase 1.5MIU Injection infusion typically take?

The duration of an infusion can vary based on the condition being treated and the patient's response. Healthcare providers determine the appropriate duration.

Q 4. Can Icikinase 1.5MIU Injection dissolve all types of blood clots?

Icikinase 1.5MIU Injection is effective for certain types of clots, but its use is limited to specific conditions. Healthcare providers choose treatments based on clot location and characteristics.

Q 5. Can Icikinase 1.5MIU Injection be used in emergency situations?

In emergency situations like heart attacks and pulmonary embolisms, Icikinase 1.5MIU Injection might be considered to quickly restore blood flow. However, alternatives are often preferred.

Q 6. What should I do if I experience any adverse effects while on Icikinase 1.5MIU Injection?

If you experience any unexpected or concerning side effects, contact your healthcare provider or seek medical attention immediately.


Fact Box of Icikinase 1.5miu Injection

Molecule name: Streptokinase

Therapeutic class:  Fibrinolytic or Thrombolytics

Pharmacological class: Thrombolytic Agent

Indications: 

1. Myocardial Infarction (heart attack)

2. Deep vein thrombosis (DVT)

3. Pulmonary embolism

4. Arterial clots

5. Peripheral arterial disease

6. Thrombosis in dialysis fistulas/grafts


References

  1. KD Tripathi, Essentials of Medical Pharmacology, Drugs affecting Coagulation, bleeding, and thrombosis, 7th edition, 2013, 626.
  2. Tetris Pharma Ltd, Electronic medicines compendium (emc), [Revised on 18th Dec 2021] [ Accessed on 25th 2023], https://www.medicines.org.uk/emc/product/13114/smpc#gref
  3. Adinarayana Kunamneni, Thaer Taleb Abed Abdelghani, Poluri Ellaiah; streptokinase--the drug of choice for thrombolytic therapy; Journal of Thrombosis and Thrombolysis; Published on Feb 2007; Accessed on 25/08/2023; https://pubmed.ncbi.nlm.nih.gov/17111203/

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