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IMFINZI 120MG INJECTION_1
IMFINZI 120MG INJECTION_2
IMFINZI 120MG INJECTION_1
22% Off

Imfinzi 120mg Injection

Prescription Required

cold-chain

Salt Composition : Durvalumab

Manufacturer : ASTRAZENECA PHARMA INDIA LTD

Origin of Medicine : United Kingdom

MRP: 45500
Price :35385
You Save :10115 (22%)

1 Vial(s) Of 2.4ml

Prepaid Only. Non-Returnable

PAP Information :    Buy 1, get 1 Free. Contact us for latest updates.


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Introduction to Imfinzi 120mg Injection

Imfinzi 120mg injection is an anticancer drug belonging to the class of Anti-PD-1 monoclonal antibodies, containing the active ingredient Durvalumab. It is used to treat non-small cell lung cancer(has not spread outside your chest ), small cell lung cancer(has spread within your lungs), and biliary tract cancers(cancer of the bile ducts). Tell your doctor if you have had an organ transplant, liver problems, lung or breathing problems, or autoimmune disease (the body’s immune system attacks its own cells) before taking this injection.

The common side effects that are likely to occur with this injection are cough, upper respiratory tract infections, feeling tired, shortness of breath, inflammation in the lungs, and rash. This medicine may increase the risk of developing immune-mediated adverse reactions like pneumonitis, colitis, hepatitis, endocrinopathies, and nephritis which have been reported.

This medicine is not recommended for adolescents and children under the age of 18. During the Durvalumab treatment, your doctor may periodically monitor your white blood cell counts, platelets, blood sugar, electrolytes, and kidney parameters to prevent serious complications. This drug is often used in combination with carboplatin or cisplatin for the treatment of small-cell lung cancer and also used in combination with gemcitabine for the treatment of biliary tract cancer. This medicine has the potential to cause kidney problems. Report to your doctor if you have been diagnosed with kidney disorders, heart failure, high blood cholesterol levels, or hypertension before starting this treatment.


Uses of Imfinzi 120mg Injection

  • Non-Small Cell Lung Cancer
  • Small Cell Lung Cancer
  • Biliary Tract Cancer

Therapeutic Effects of Imfinzi 120mg Injection

It works by blocking a protein called programmed death-ligand 1 (PD-L1), which is found on the surface of certain cancer cells. When PD-L1 binds to its receptor on T cells, it can inhibit the immune system's ability to recognize and attack cancer cells.  By blocking the interaction between PD-L1 and its receptor, durvalumab allows T cells to recognize and attack cancer cells more effectively. Durvalumab helps the immune system to fight cancer and potentially slow or stop its growth.


Interaction of Imfinzi 120mg Injection with other drugs

Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Imfinzi 120mg injection and reduce effectiveness by causing undesirable side effects.


More Information about Imfinzi 120mg Injection

  • Store Imfinzi 120mg injection in the refrigerator at (2°C to 8°C).
  • Do not freeze.
  • Keep it out of reach from children.

How to consume Imfinzi 120mg Injection

Durvalumab is a prescription drug available in injection form. This injection will be given intravenously into a vein in your arm or hand by a healthcare professional in a hospital setting. Do not self-administer this medicine. The dose of the injection will be decided by your doctor based on your disease condition and other factors. During the infusion, you will be monitored for any side effects or reactions to the medication. The infusion usually takes a few hours to complete, and you may need to receive multiple infusions over the course of several weeks.


Safety Advices for Imfinzi 120mg Injection

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Pregnancy

  

Imfinzi 120mg injection is not recommended for pregnant women as it may cause fetal harm. Consult your doctor if you are pregnant or planning for pregnancy during the treatment.

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Breast Feeding

  

It is not known if Imfinzi 120mg injection passes into your breast milk or if it will affect your baby. Please consult your doctor before breastfeeding. 

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Lungs

  

Consult your doctor if you have any lung diseases before starting the treatment.

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Liver

  

Inform your doctor if you have any liver problems before taking Imfinzi 120mg injection. Regular monitoring of liver function tests is recommended.

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Alcohol

  

It is unknown whether consuming alcohol interacts with Imfinzi 120mg injection. Please consult your doctor for more advice.

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Driving

  

It is unsafe to drive vehicles or operate heavy machinery after taking Imfinzi 120mg injection, it may cause dizziness and impair your concentration.


Side Effects of Imfinzi 120mg Injection

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

Serious

  • Infection (chills, increased temperature)
  • serious lung infections (pneumonia)
  • fungal infection in the mouth
  • tooth and mouth soft tissue infections
  • flu-like illness
  • overactive thyroid gland that can cause fast heart rate or weight loss
  • inflammation of the lungs (pneumonitis)
  • hoarse voice (dysphonia)
  • abnormal liver tests (aspartate aminotransferase increased; alanine aminotransferase increased)  night sweats
  • muscle pain (myalgia)
  • abnormal kidney function tests (blood creatinine increased)
  • painful urination
  • swelling of the legs (oedema peripheral)
  • reaction to the infusion of the medicine that can cause fever or flushing

Common

  • Cough
  • upper respiratory tract infections
  • feeling tired
  • shortness of breath
  • inflammation in the lungs
  • rash

Word of Advice

Imfinzi 120mg injection has the tendency to cause harm to unborn fetus. Inform your healthcare provider before starting this treatment if you are pregnant, or have a partner who can become pregnant. Your healthcare provider will conduct a pregnancy test before you start treatment with Durvalumab Tablet. Discuss effective birth control methods with your healthcare provider and use them during treatment and for 8 weeks after your last dose. It is not known if Durvalumab passes into breast milk. Hence, it is not recommended to breastfeed during this treatment. This drug can increase your risk of sunburn and skin damage, so it is important to wear protective clothing and sunscreen while moving outdoors.  If you experience any gastrointestinal symptoms, such as diarrhea, abdominal pain, or nausea, be sure to inform your doctor immediately so that he may prescribe you antiemetic medicines also to prevent the symptoms.


FAQs

Q 1. How will I receive Imfinzi 120mg injection?

Imfinzi 120mg injection is administered intravenously into a vein in your arm or hand by a healthcare professional.

Q 2. How does Imfinzi 120mg injection work?

It works by blocking a protein called programmed death-ligand 1 (PD-L1), which is found on the surface of certain cancer cells. When PD-L1 binds to its receptor on T cells, it can inhibit the immune system's ability to recognize and attack cancer cells. By blocking the interaction between PD-L1 and its receptor, durvalumab allows T cells to recognize and attack cancer cells more effectively. Durvalumab helps the immune system to fight the cancer and potentially slow or stop its growth.

Q 3. Can Imfinzi 120mg injection be used in combination with other drugs?

Yes, Imfinzi 120mg injection is often used in combination with other immunotherapy drugs, such as tremelimumab, to boost the immune response against cancer cells.

Q 4. Whether Imfinzi 120mg injection is safe to use during pregnancy?

Imfinzi 120mg injection is not recommended during pregnancy and it is unsafe because it may harm a developing fetus. Women who are pregnant or planning to become pregnant should discuss their treatment options with their doctor immediately.

Q 5. Who should not take a Imfinzi 120mg injection?

This drug is not recommended in patients with autoimmune diseases, such as lupus, rheumatoid arthritis, or multiple sclerosis, who may be at an increased risk of side effects from Durvalumab, and it should be used with caution in these patients.


Fact Box of Imfinzi 120mg Injection

Molecule name: Durvalumab

Therapeutic class: Anticancer

Pharmacological class: Anti-PD-1 monoclonal antibodies

Indications: 

1. Non-Small Cell Lung Cancer

2. Small Cell Lung Cancer

3. Biliary Tract Cancers


References

  1. AstraZeneca Pharmaceuticals LP, US Food and Drug Administration, [ Revised on Sep 2022] [ Accessed on 28th March 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2022/761069s035lbl.pdf
  2. AstraZeneca UK Limited, Electronic medicines compendium (EMC), [ Revised on Dec 2020] [ Accessed on 28th March 2023], https://www.medicines.org.uk/emc/files/pil.9495.pdf
  3. Ema (2022) Imfinzi, European Medicines Agency. Available at: https://www.ema.europa.eu/en/documents/product-information/imfinzi-epar-product-information_en.pdf [Accessed on 28th March 2023].

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