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Keytruda 100mg Injection
Last updated on 31 Mar 2026 | 09:31 AM (IST)
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Keytruda 100 mg Injection is a prescription anticancer medicine used to treat various types of cancer, including melanoma, lung cancer, head and neck cancer, and certain other solid tumors. It contains pembrolizumab, an immunotherapy drug that works by blocking the PD-1 pathway, helping the immune system recognize and attack cancer cells. Keytruda is administered under strict oncologist supervision as part of a personalized cancer treatment plan.
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Keytruda 100mg Injection
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MSD PHARMACEUTICALS PVT LTD
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Introduction to Keytruda 100mg Injection
Keytruda 100mg Injection is an immunotherapy medication containing the active constituent pembrolizumab. It is used to treat cancers in the skin, lungs, bladder, stomach, liver, gallbladder, cervix, kidney, colon, rectum, esophagus, breast, and uterus cancers. It is used to treat head and neck cancer and classical Hodgkin lymphoma (a type of blood cancer). Cancer is a disorder in which cells multiply in an uncontrolled and abnormal manner. It can lead to durable responses and improved survival in some patients with advanced cancer. It can improve overall survival in patients with several types of advanced cancer. However, not all patients respond to it, and some may experience side effects.
Keytruda 100mg Injection is not recommended for adolescents and children under 18 years of age, except for children with classical Hodgkin lymphoma aged three years and older. Use effective birth control during the treatment and for at least four months after the last dose. As with any cancer treatment, the decision to use it will depend on several factors, including the type and stage of cancer, the patient's overall health, and other treatments the patient has received. Patients should discuss the potential risks and benefits with their healthcare provider.
Uses of Keytruda 100mg Injection
- Advanced melanoma
- Non-small cell lung cancer
- Classical Hodgkin lymphoma
- Urothelial carcinoma
- Gastric cancer
- Head and neck squamous cell carcinoma
- Cervical cancer
- Primary mediastinal large B-cell lymphoma
Therapeutic Effects of Keytruda 100mg Injection
The therapeutic effect of pembrolizumab is the activation of the immune system to identify and attack cancer cells in the body. It is a type of immunotherapy drug that blocks a protein called PD-1 present in immune cells, which allows the immune system to identify and attack cancer cells more effectively. By doing so, this drug can help slow or inhibit the spread and growth of cancer cells in the body.
Interaction of Keytruda 100mg Injection with other drugs
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Keytruda 100mg Injection and reduce effectiveness by causing undesirable side effects.
More Information about Keytruda 100mg Injection
- Keytruda 100mg Injection should be kept refrigerated between 2°C and 8°C (36°F to 46°F).
- This medication should be protected from light and kept in its original packaging until the time of use.
- Keep it out of reach from children and pets.
How to consume Keytruda 100mg Injection
Keytruda 100mg Injection is a medication that is administered by a healthcare professional, typically in a hospital or clinic setting. The medication is given as an intravenous (IV) infusion. The dosage and frequency will depend on the type and stage of the cancer, as well as the patient's overall health and response to the medication. The medication is typically given every three to four weeks, and the number of treatment cycles varies with the type and staging of cancer and the patient's response to the drug. During the infusion, the patient will be monitored by a healthcare professional for any potential side effects or reactions to the medication.
Safety Advice for Keytruda 100mg Injection
Breast Feeding
If women is taking then it is a potential risk of harm to a nursing infant. Breastfeeding women should discuss the potential risks and benefits of the medication with their healthcare provider before starting treatment.
Alcohol
It is generally recommended that patients taking Keytruda 100mg Injections avoid or limit their alcohol intake, as alcohol increases the risk of liver damage and exacerbates any liver-related side effects.
Liver
Keytruda 100 mg Injection can affect liver function, and patients with pre-existing liver disease or abnormalities may be at increased risk of liver damage. Patients should tell their healthcare provider if they have a history of liver disease or abnormal liver function tests because it is unsafe to use this drug with pre-existing liver disease.
Lungs
Keytruda 100mg Injection has been associated with mild lung-related side effects, although these are relatively uncommon. You should consult the doctor if you have any lung diseases before starting the treatment.
Driving
Patients receiving Keytruda 100mg Injection should avoid driving or operating machinery if they experience side effects such as fatigue, dizziness, or blurred vision, impairing a patient's ability to drive or operate machinery safely.
Pregnancy
Keytruda 100mg Injection is unsafe for a developing fetus, and it is not recommended for use during pregnancy.
Side Effects of Keytruda 100mg Injection
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious
- Pneumonitis (inflammation of the lungs).
- Hepatitis (inflammation of the liver).
- Colitis (inflammation of the colon).
- Hypothyroidism or hyperthyroidism.
- Adrenal insufficiency (decreased adrenal function).
- Type 1 diabetes.
Common
- Fatigue
- Nausea
- Loss of appetite
- Diarrhea or constipation
- Skin rash or itching
- Headache
- Muscle or joint pain
- Cough or shortness of breath
- Fever or chills
- Low blood cell counts
Word of Advice
It is important to follow the healthcare provider's instructions carefully when receiving treatment with Keytruda 100mg Injection or any other medication. One of the most essential things you can do is attend all scheduled appointments. It will allow your healthcare provider to monitor your progress, check for any potential side effects, and adjust your treatment plan as needed. In addition to attending appointments, it is important to report any symptoms or side effects to your healthcare provider as soon as possible. women in reproductive age se effective birth control during the treatment and for at least four months after the last dose. Nursing women should avoid breastfeeding during treatment. Maintaining a healthy lifestyle while receiving treatment with Keytruda 100mg Injection is also essential. It includes eating a balanced diet, getting enough rest, and engaging in regular physical activity, as the healthcare provider recommends. Finally, being patient and staying positive throughout the treatment process is essential. Staying positive and optimistic can help you stay motivated and focused on your recovery.
FAQs about Keytruda 100mg Injection
Q1.
How is the effectiveness of Keytruda 100mg Injection measured?
The effectiveness of Keytruda 100mg Injection is measured by imaging tests, such as CT (computed tomography) scans or MRIs (magnetic resonance imaging), to monitor the tumor's size and growth. A reduction in tumor size or stabilization is considered a positive response to treatment.
Q2.
Can Keytruda 100mg Injection cause depression or anxiety?
Depression and anxiety have been reported as rare side effects while taking taking this medication. Patients should inform their healthcare provider if they experience new or worsening mental health symptoms while taking Keytruda 100mg Injection.
Q3.
What are the Potential Side Effects of Keytruda 100mg Injection?
The potential side effects of Keytruda 100mg Injection include fatigue, nausea, loss of appetite, skin rash or itching, headache, muscle or joint pain, cough or shortness of breath, and low blood cell counts. Immune-mediated side effects may also occur, such as inflammation of the lungs, liver, or colon, changes in thyroid function, decreased adrenal function, or autoimmune destruction of insulin-producing cells.
Q4.
How can side effects be managed?
Side effects may be managed through dose adjustment, supportive care, or medication. In some cases, treatment with it may need to be stopped if side effects are severe or life-threatening.
Q5.
Can patients continue to work or perform daily activities while taking Keytruda 100mg Injection?
Many patients are able to continue working and performing daily activities while taking Keytruda 100mg Injection. However, some patients may experience side effects that affect their ability to work or perform daily activities, such as fatigue or nausea.
Q6.
Can Keytruda 100mg Injection cure cancer?
Keytruda 100mg Injection can lead to long-lasting remissions in some patients, but it is not a cure for cancer. Patients should discuss their individual treatment plan and expected outcomes with their healthcare provider.
Q7.
Can Keytruda 100mg Injection be used in combination with other cancer treatments?
Yes, Keytruda 100mg can be combined with other cancer treatments such as chemotherapy, radiation therapy, and targeted therapy. Combining it with other cancer treatments may provide better outcomes than either treatment alone.
Q8.
In how much time will the drug show effect?
The time it takes for Keytruda 100mg Injection to show its effect can vary depending on the type and stage of the cancer being treated. In some cases, patients may see a response within a few weeks of starting treatment, while in other cases, it may take several months.
Fact Box of Keytruda 100mg Injection
Molecule name: Pembrolizumab
| Therapeutic class: Anticancer |
Pharmacological class: Monoclonal Antibody | Indications: 1. Advanced melanoma 2. Non-small cell lung cancer 3. Classical Hodgkin lymphoma 4. Urothelial carcinoma 5. Gastric cancer 6. Head and neck squamous cell carcinoma 7. Cervical cancer 8. Primary mediastinal large B-cell lymphoma |
References
Merck Sharp & Dohme (UK) Limited, European Medicines Agency (emc), [Revised on Nov 2022], [ Accessed on 30th March 2023], https://www.ema.europa.eu/en/documents/procedural-steps-after/keytruda-epar-procedural-steps-taken-scientific-information-after-authorisation_en.pdf
Merck, U.S. Food and Drug Administration, Highlights of Prescribing Information: Pembrolizumab, [Last revised 2023], [Accessed on 30th March 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2023/125514s128lbl.pdf
Goodman and Gilman's, The Pharmacological Basis of Therapeutics, 13th Edition, 2018, 1026,
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Author Details
Written By
Sakshi Anil More
B. Pharm
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 31 Mar 2026 | 09:31 AM (IST)
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