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19% Off

Lanvis 40mg Tablet

Prescription Required

Salt Composition : Thioguanine

Manufacturer : GLAXO SMITHKLINE PHARMACEUTICALS LTD

Origin of Medicine : India

MRP: 950
Price :768
You Save :182 (19%)

30 Tablet(s) In A Bottle

Out of Stock

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Introduction to Lanvis 40mg Tablet

Lanvis 40mg Tablet consists of the active ingredient as thioguanine. It is indicated to treat blood problems and cancers, namely acute myelogenous leukemia (AML) and acute lymphoblastic leukemia (ALL). Acute myelogenous leukemia is a rapidly progressing disorder that increases the number of white blood cells produced by the bone marrow. This can cause infections and bleeding. Acute lymphoblastic leukemia (ALL) refers to the accumulation of white blood cells that have not matured due to the abnormal production of white blood cells in the bone marrow. This condition is more prevalent among children aged below 5.

Lanvis 40mg Tablet in studies has also been shown to have a relatively low risk of causing nausea and vomiting compared to other chemotherapy drugs. Additionally, because it is taken orally, it may be more convenient for some patients than intravenous chemotherapy. Patients should also avoid consuming grapefruit or grapefruit juice while taking Lanvis 40mg Tablet, as it can interfere with the metabolism of the drug and increase the risk of side effects.


Uses of Lanvis 40mg Tablet

Lanvis 40mg Tablet uses in the treatment of the following:

  • Acute lymphoblastic leukemia (ALL)
  • Acute myelogenous leukemia (AML)

Therapeutic Effects of Lanvis 40mg Tablet

Lanvis 40mg Tablet is an antimetabolite medication that interferes with the DNA and RNA synthesis process in cancer cells, causing them to undergo programmed cell death, or apoptosis. By preventing the growth and spread of cancer cells, it can help to induce remission or prolong survival for patients with leukemia. This medicine is often used in combination with other chemotherapy drugs to increase its effectiveness.


Interaction of Lanvis 40mg Tablet with other drugs

Inform your healthcare provider about all your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Lanvis 40mg Tablet and reduce effectiveness by causing undesirable side effects.


More Information about Lanvis 40mg Tablet

  • Store at a cool temperature of 68°F and 77°F (20°C and 25°C).
  • Protected from light.
  • Keep it in its original packaging until it is ready to be used.
  • Keep out of the reach of children and pets.
  • Should be disposed of properly.

How to consume Lanvis 40mg Tablet

Lanvis 40mg Tablet is usually taken orally in the form of tablets. The tablets should be swallowed whole with water or another liquid, and should not be crushed, chewed, or broken. It is generally recommended to take it on an empty stomach, either one hour before or two hours after meals, to help maximize its absorption and effectiveness. Do not take a double dose to make up for a missed one.


Safety Advices for Lanvis 40mg Tablet

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Pregnancy

  

Lanvis 40mg Tablet may harm the developing fetus, so it is unsafe to use during pregnancy.

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Breast Feeding

  

Lanvis 40mg Tablet is not recommended during breastfeeding. The drug may be excreted in breast milk and could potentially harm the nursing infant.

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Lungs

  

In studies, it has been seen that Lanvis 40mg Tablet does not cause any harm to the lungs. But patients with pre-existing lung disease should disscuss with the doctor before taking this medication.

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Liver

  

Lanvis 40mg Tablet can cause liver toxicity, particularly in patients with pre-existing liver disease or other medical conditions that affect liver function. Patients with liver disease may be at higher risk for developing liver toxicity while treatment with this medicine.

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Alcohol

  

There is no known interaction between Lanvis 40mg Tablet and alcohol. However, it is important to note that alcohol consumption can harm overall health and potentially exacerbate underlying medical conditions. So patients should consult their healthcare provider before taking alcohol during treatment.

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Driving

  

Lanvis 40mg Tablet can cause dizziness, fatigue, and other central nervous system side effects, which may impair your ability to drive or operate machinery safely. Therefore, it is important to use caution when driving or performing tasks that require mental alertness while treatment.


Side Effects of Lanvis 40mg Tablet

Like all medications, Lanvis 40mg Tablet cause some side effects, although not every person who takes it will experience them. 

Serious:

  • Unexpected bleeding or bruising
  • Infections
  • Yellow skin and eyes
  • Liver toxicity
  • Stevens-Johnson syndrome (life-threatening skin reaction)
  • Tumor lysis syndrome (cancer cells release large amounts of toxins into the blood)

Common:

  • Low number of blood cells and platelets
  • Tiredness
  • Nausea
  • Pruritus
  • Dark urine
  • Rash
  • Fever
  • Vomiting
  • Diarrhea
  • Mouth ulcers
  • Decreased kidney functions

Word of Advice

If you are taking Lanvis 40mg Tablet, it is important to discuss any concerns with your healthcare provider. Patients with a history of allergy to this medication or any of these components should avoid taking it. Pregnant and breastfeeding women should be avoided while taking this medication. Women of reproductive potential should take contraceptives during and after several weeks of treatment. Patients should avoid the consumption of grapefruit during treatment. Falls and sharp cuts should be avoided as this medication increases the tendency of bleeding and raises the risk of infection. Always follow the dosing instructions and precautions provided by your doctor, and report any side effects or adverse reactions to your healthcare provider. Never stop or modify your medication regimen without consulting your healthcare provider.


FAQs

Q 1. Can Lanvis 40mg Tablet be used during radiation therapy?

Lanvis 40mg Tablet may interact with radiation therapy and may not be safe for use during treatment. If you are undergoing radiation therapy or planning to, discuss your options with your healthcare provider.

Q 2. Can I take Lanvis 40mg Tablet if I have tuberculosis?

The use of Lanvis 40mg Tablet may not be recommended if you have tuberculosis (TB). It can suppress the immune system, which can increase the risk of developing infections such as TB or reactivating latent TB infections. If you have active TB or a history of TB, it is important to discuss this with your healthcare provider before starting treatment with this medication.

Q 3. Can I take this medicine if I have kidney stones?

The use of Lanvis 40mg Tablet may not be recommended if you have a history of kidney stones or impaired kidney function. It can increase the levels of uric acid in the body, which can contribute to the formation of kidney stones. In addition, this medication is eliminated from the body primarily through the kidneys, so impaired kidney function can affect the clearance of the drug from the body, leading to a higher risk of side effects.

Q 4. How Lanvis 40mg Tablet will affect my heart?

Lanvis 40mg Tablet can affect the function of the heart and blood vessels, leading to conditions such as hypertension (high blood pressure) and cardiomyopathy (disease of the heart muscle). The risk of these side effects may be increased if you have a history of heart disease or if you take other medications that can affect the heart.

Q 5. Can Lanvis 40mg Tablet cause hair loss?

Hair loss is not a common side effect of Lanvis 40mg Tablet, but it may occur in some people. If you experience hair loss while taking it, discuss it with your healthcare provider.

Q 6. Does Lanvis 40mg Tablet affect fertility?

Lanvis 40mg Tablet may affect fertility in men and women, but the extent of the effect is not well-established. If you are concerned about fertility, discuss your options with your healthcare provider.


Fact Box of Lanvis 40mg Tablet

Molecule name: Thioguanine

Therapeutic class: Antineoplastic

Pharmacological class: Antimetabolites 


 

Indications: 

1. Acute lymphoblastic leukemia (ALL)

2. Acute myelogenous leukemia (AML)


References

  1. Aspen Pharma Trading Limited, Electronic Medicines Compendium (EMC), [Revised on Sep 2017] [Accessed on 27th April 2023], https://www.medicines.org.uk/emc/files/pil.4654.pdf
  2. H.G. Watson, J.I.O. Craig, L.M. Manson, Blood disease, Davidson’s Principles and Practice of Medicine, 22nd Edition, 2014, 989-1056.
  3. Edward Chu, Cancer Chemotherapy, Lange’s Basic and Clinical Pharmacology, 14th Edition, 2018, 948-976
  4. Apsen Global Inc, U.S Drud and Food Safety Administration (FDA), [Revised on May, 2018], [Accessed on 27th April 2023]https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/012429s028lbl.pdf

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