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Salt Composition : Ledipasvir,sofosbuvir
Manufacturer : ZYDUS CADILA
Origin of Medicine : India
28 Tablet(s) In A Bottle
Introduction to Ledihep Tablet
Ledihep Tablet is a medicine that contains the active substances ledipasvir and sofosbuvir. It is indicated to treat chronic (long-term) hepatitis C virus infection in adults and children three years of age and older. Hepatitis C is a virus that mainly infects the liver. It is mainly triggered by a virus named Flavivirus. Most patients remain asymptomatic, and the symptoms show up only when they develop chronic liver disease or cirrhosis. The progression of liver disease is faster in people who consume alcohol and those with a weak immune system. The main treatment goal for Hepatitis C infection is complete eradication of the virus causing this infection.
This drug is contraindicated for individuals with decompensated cirrhosis or severe liver disease. In such cases, alternative treatment options should be considered. This drug should not be used if you have any known allergy or hypersensitivity to Ledihep Tablet or other ingredients in the medication. Your liver function may change with the treatment of hepatitis C and, therefore, affect other medications (e.g., medicines used to suppress your immune system, etc.). Your doctor may need to monitor your other medicines and make dose adjustments closely. If you have liver disease other than hepatitis C, are awaiting a liver transplant, have a current or previous infection with the hepatitis B virus (HBV), or receive ongoing treatment for HIV infection. It's important to inform your doctor. They will consider these conditions before starting treatment.
Talk to your doctor immediately before taking this drug if you have diabetes. You may need closer monitoring of your blood glucose levels or adjustment of your diabetes medication after starting this drug. Some diabetic patients have experienced low sugar levels in the blood (hypoglycemia) after starting treatment with medicines like Ledihep Tablet. The doctor will test your blood before, during, and after your treatment with this medicine. So that your doctor can confirm that your treatment has worked and you are free of the hepatitis C virus, do not breastfeed during treatment with this tablet. It is unknown whether this drug passes into human breast milk. Consult your doctor if you are breastfeeding. Do not give this tablet to children under three years of age. The use of this drug has not yet been studied. This tablet can interact with certain medications, potentially affecting their efficacy or increasing the risk of side effects. It's necessary to inform your doctor about all your medications, including prescription, over-the-counter, and herbal supplements, to ensure no potential interactions.
Uses of Ledihep Tablet
- Chronic Hepatitis C virus infection.
Therapeutic Effects of Ledihep Tablet
The active substances in the Ledihep Tablet work together by blocking two different proteins that the virus needs to grow and reproduce itself, allowing the infection to be permanently eliminated from the body.
Interaction of Ledihep Tablet with other drugs
Inform your doctor about all your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications, including rifampicin, rifabutin, St. John's wort, carbamazepine, phenobarbital, phenytoin, and rosuvastatin, may interact with Ledihep Tablet, reducing effectiveness by causing undesirable side effects.
More Information about Ledihep Tablet
- Store the Ledihep Tablet at a controlled room temperature of (30°C).
- Keep it out of reach of children.
How to consume Ledihep Tablet
It is an orally available prescription drug. Your doctor will decide the dose and duration of Ledihep Tablet based on the disease condition and other factors. Always take this medicine as prescribed by your doctor. Take the tablet with or without food. Do not break, chew, or crush the tablet. Swallow the whole tablet with water.
Safety Advices for Ledihep Tablet
The effects of this tablet during pregnancy are not known. If you are pregnant or plan to have a baby, consult your doctor before taking Ledihep Tablet.
Do not breastfeed during treatment with Ledihep Tablet. It is unknown whether this drug passes into human breast milk. Consult your doctor if you are breastfeeding.
Patients with pre-existing lung disease should consult a healthcare provider before taking Ledihep Tablet.
Ledihep Tablet should be cautiously administered in patients with liver diseases. Dose adjustments are necessary. However, inform your physician of any liver diseases before initiating the therapy.
It is unknown whether alcohol may interact with Ledihep Tablet. Inform your physician if you drink alcoholic beverages.
The Ledihep Tablet, is known to affect driving ability. It is unsafe to ride a bike or operate machines.
Side Effects of Ledihep Tablet
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
- Allergic reactions
Word of Advice
It is always advised to take this tablet exactly as your doctor said. If you accidentally take more than the prescribed dose, you should immediately contact your doctor or the nearest emergency department for advice. Keep the tablet bottle with you to describe what you have taken easily. This medicine contains lactose as an inactive ingredient that the body cannot digest lactose, a sugar found in milk and dairy products. It can cause symptoms such as bloating and abdominal pain. If you have lactose intolerance, inform your doctor before starting this therapy.
Do not stop taking this tablet unless your doctor tells you to. Complete the entire course of treatment to give the medicine a great chance to treat your hepatitis C virus infection. Talk with your pharmacist, doctor, or nurse if you have further doubts regarding Ledihep Tablet.
Q 1. What types of hepatitis C do Ledihep Tablet treat?
Ledihep Tablet are effective against multiple genotypes (strains) of the hepatitis C virus, including genotypes 1, 4, 5, and 6. It may also be used in certain cases of genotype three infections, but the treatment duration and additional medications may vary.
Q 2. How can I get Ledihep Tablet?
Ledihep Tablet, is a prescription medication, which means you will need a prescription from a healthcare provider to obtain it. Your doctor will evaluate your situation, including your HCV genotype, liver function, and medical history, to determine if this tablet is right for you. Once you have a prescription, you can get it from a pharmacy.
Q 3. Can Ledihep Tablet interact with other medications?
Ledihep Tablet may interact with certain medications, including rifampicin, rifabutin, St. John's wort, carbamazepine, phenobarbital, phenytoin, and rosuvastatin. Inform your physician about all your medications, supplements, and herbal products to avoid potential interactions.
Q 4. How does the Ledihep Tablet work?
Ledihep Tablet, is an antiviral medication that works by targeting specific proteins in the hepatitis C virus, preventing its replication, and reducing the amount of virus in the body.
Q 5. Who should not take Ledihep Tablet?
You should avoid taking the tablet if you have an allergy or hypersensitivity to Ledihep Tablet, or other ingredients.
Q 6. How long is the treatment with Ledihep Tablet?
The treatment duration with Ledihep Tablet can be varied on factors such as the specific genotype of the hepatitis C virus and any liver damage. In many cases, treatment can last for 8 to 12 weeks.
Fact Box of Ledihep Tablet
Molecule name: Ledipasvir, Sofosbuvir
Therapeutic class: Antiviral
Pharmacological class: Direct-acting antiviral agents (DAAs)
Indications: Chronic hepatitis C virus (HCV) infection.
- Gilead Sciences Ltd., Electronic Medicines Compendium (EMC), [Revised on Jan 2021] [Accessed on 16 May 2023], https://www.medicines.org.uk/emc/files/pil.11849.pdf
- Sharon Safrin, Antiviral Agents, Lange's Basic and Clinical Pharmacology, 14th Edition, 2018, 863-894.
- Q.M. Anstee, D.E.J. Jones, Liver, and biliary tract disease, Davidson's Principles and Practice of Medicine, 22nd Edition, 2014, 921-988.
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