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Letronat 2.5mg Tablet 10's
Salt Composition : Letrozole
Manufacturer : NATCO PHARMA LTD
Origin of Medicine : India
10 Tablet(s) In A Strip
Introduction to Letronat 2.5mg Tablet 10's
Letronat 2.5mg is an anti-cancer drug that belongs to the class aromatase inhibitor. It is indicated as a supportive therapy after the main therapy or first-line therapy for postmenopausal women with early and advanced breast cancer whose tumors are hormone receptor-positive. Since high amounts of estrogen are found to trigger breast cancer, this medicine reduces the levels of the female reproductive hormone by blocking the enzyme (aromatase) that is involved in the production of estrogen. This medicine aims to slow or stop the growth and/or spreading to other body parts.
Inform your physician if you have not attained menopause yet, as this medicine does not work for premenopausal women. Since this medicine tends to reduce the levels of female reproductive hormones, it is not advised for menstruating women as it is related to causing fertility issues. It is advised to keep track of your cholesterol levels as this medicine tends to elevate cholesterol levels. Letronat 2.5mg could also decrease bone mineral density. Hence, discuss with your physician and consider monitoring your bone parameters regularly. It is advised to use effective birth control during the treatment and at least 3 weeks after the last dose.
Uses of Letronat 2.5mg Tablet 10's
- First and second-line treatment of postmenopausal women with hormone receptor-positive breast cancer.
- Supportive to standard treatment for postmenopausal women with early breast cancer.
- Treatment for unknown advanced breast cancer in postmenopausal women.
- Extended supportive therapy for postmenopausal women with early breast cancer who have already taken other anti-cancer medication.
Therapeutic Effects of Letronat 2.5mg Tablet 10's
The growth of some cancers in breasts is stimulated by estrogens. Letronat 2.5mg tablet is a nonsteroidal compound that inhibits estrogen production by blocking the enzyme aromatase. This medicine reduces the tumor size and stops or slows the progression of the disease, avoiding the reoccurring of early-stage breast cancer and improving the survival rate.
Interaction of Letronat 2.5mg Tablet 10's with other drugs
Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, or herbal products you take or have taken before the treatment. Certain medications may interact with Letronat 2.5mg and cause undesirable side effects.
More Information about Letronat 2.5mg Tablet 10's
- Keep the tablets away from the reach of children and pets.
- Store Letronat 2.5mg Tablets at an optimal temperature not exceeding 25°C.
How to consume Letronat 2.5mg Tablet 10's
It is advised to consume Letrozole Tablets exactly as your doctor prescribes. It can be consumed with or without food and should be swallowed with a glass of water. Letronat 2.5mg can be taken with or without food. It is better to take the tablet at a fixed time. Do not break, chew or crush the tablet.
Safety Advices for Letronat 2.5mg Tablet 10's
Letronat 2.5mg tablet are highly unsafe during pregnancy because they may cause harm to the unborn baby. Discuss with your doctor about effective contraceptive methods. It is recommended to consult your physician if you are pregnant or may be pregnant.
It is unsafe to breastfeed your baby when taking Letronat 2.5mg tablet. It is advised to avoid breastfeeding for at least three weeks after the last dose of the medicine.
Inform your physician if you have liver disease, as the Letronat 2.5mg tablet is not recommended for patients with severe liver disease. Dose adjustment may be required.
Certain lung diseases can occur while using Letronat 2.5mg tablet. Consult your doctor if you have lung disease.
It is not recommended to consume alcohol while you are on the treatment with Letronat 2.5mg tablet as it may cause serious complications.
Caution is required while driving and operating machinery when you take Letronat 2.5mg tablet causes dizziness, sleepiness, and tiredness.
Side Effects of Letronat 2.5mg Tablet 10's
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
- Decreased red blood cells
- Decreased bone mineral density
- Fluid build up in lungs
- Swelling in the face, eyes, feet, and legs
- Hot sweats and excessive sweating
- Hypercholesterolemia (high cholesterol)
- Heart palpilation
- Loss of appetite
- Nausea and Vomiting
- Muscle pain, bone pain, and joint stiffness
- Dizziness, tiredness, and sleepiness
- Breathing difficulty
Word of Advice
Notify your doctor if you have osteoporosis or bone fractures, as this medication is contraindicated for these conditions. Regular monitoring of bone mineral density is necessary while using Letronat 2.5mg tablet. Discuss with your doctor if you are planning a pregnancy or have not yet gone through menopause, as it may affect fertility. Inform your doctor of any sugar intolerance, as the tablet contains lactose ingredients. If you miss a dose, do not double dose; instead, resume your regular schedule.
Q 1. How does Letronat 2.5mg tablet work?
Letronat 2.5mg tablet is an anti-estrogen medication. It reduces estrogen levels in your body by inhibiting the enzyme aromatase, which is responsible for estrogen production. Estrogen stimulates the growth of certain types of breast cancer in your body. Reduced estrogen production may prevent cancer from spreading.
Q 2. Can Letronat 2.5mg cause mood changes?
Mood changes, such as depression or anxiety, are not common side effects of Letronat 2.5mg. However, if you experience any changes in mood while taking the medicine, it's important to talk to your doctor.
Q 3. What are the serious side effects of the Letronat 2.5mg tablet?
The serious side effects do not occur in everyone; very few people experience them. The serious side effects of the Letronat 2.5mg tablet include stroke, angina, heart attack, blood clotting, cataract, osteoporosis, and fluid build-up in the lungs.
Q 4. Is it better to take Letronat 2.5mg in the morning or at night?
Your doctor should determine the timing for taking Letronat 2.5mg based on your specific needs and medical condition. Always follow the doctor's instructions.
Q 5. How often should I have my bone density checked while taking Letronat 2.5mg ?
Letronat 2.5mg can increase the risk of bone fractures in some people, so it's important to have regular bone density checks while taking the medication. Your doctor will recommend how often you should have these checks.
Q 6. How long is Letronat 2.5mg taken?
The duration of treatment with Letronat 2.5mg depends on the specific medical condition and individual response. Follow your doctor's instructions and only stop taking the medication if advised.
Fact Box of Letronat 2.5mg Tablet 10's
Molecule name: Letrozole
Therapeutic class: Aromatase Inhibitor
Pharmacological class: Anti-Neoplastic drug
Indications: Treatment for early breast cancer in postmenopausal women
- Cipla (EU) Limited, Electronic Medicines Compendium (EMC), [Revised on Oct 2021], [Accessed on 22th Mar 2023], https://www.medicines.org.uk/emc/files/pil.9957.pdf
- Novartis Pharmaceuticals Corporation, [Revised on May 2020], [Accessed on 22th Mar 2023], https://www.novartis.us/sites/www.novartis.us/files/Femara.pdf?TB_iframe=true
- Highlights of prescribing information. (n.d.), US Food and Drug Administration [Accessed on 22th Mar 2023]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/020726s027lbl.pdf
- Edward Chu, Cancer Chemotherapy, Lange’s Basic and Clinical Pharmacology, 14th Edition, 2018, 948-976.
- KD Tripathi, Estrogens, Progestins and Contraceptives, Essentials of Medical Pharmacology, 8th Edition, 2019, 330-353.
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