LYNPARZA 150MG TABLET

Introduction:

Lynparza 150 mg Tablet is a targeted therapy containing the active constituent olaparib. It is used to treat ovarian cancer, breast cancer, pancreatic cancer, and prostate cancer. Cancer is a disease in which cells multiply in an uncontrolled and abnormal manner. This medication can be given alone or in combination with other anticancer medications.

Before taking Lynparza 150 mg Tablet, you need to inform your physician if you have lung disorders, kidney problems, allergic conditions, or other diseases. Use effective birth control during the treatment and for at least 3 months after the last dose. You should not drink grapefruit juice or eat grapefruits during the treatment as it can affect how the medication works.

Lynparza 150 mg may affect the way some medications work. Before taking this medication, you should tell your physician about all the medicines you have been taking recently, including supplements and herbal medicines. Do not take more than recommended.

Uses of Lynparza 150 mg Tablet:

• Ovarian cancer
• Breast cancer
• Prostate cancer
• Pancreatic cancer

How Lynparza 150mg Tablet works:

Lynparza 150 mg Tablet inhibits the poly (ADP-ribose) polymerase (PARP) enzymes, damages the genetic material (DNA) and prevents the growth and multiplication of cancer cells.

Interactions with other drugs:

Inform your doctor about any medications you are taking or have taken before the treatment.

More information:

• Keep Lynparza 150mg Tablet out of sight and reach of children.

References:

1. AstraZeneca UK Limited, Electronic medicines compendium (emc), [Revised on Jan 2021] [ Accessed on 2nd Dec 2021], https://www.medicines.org.uk/emc/files/pil.9204.pdf
2. AstraZeneca Pharmaceuticals LP, US Food and Drug Administration, [Revised on Jan 2018] [ Accessed on 2nd Dec 2021], https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/208558s001lbl.pdf
3. Sylvia Bochum, Stephanie Berger, Uwe M Martens; Olaparib; Recent Results in Cancer Research; Published on 2018; Accessed on 02/12/2021; https://pubmed.ncbi.nlm.nih.gov/30069770/
4. Xiao Xia Guo et al; The efficacy and safety of olaparib in the treatment of cancers: a meta-analysis of randomized controlled trials; Cancer Management and Research; Published on Aug 2018; Accessed on 02/12/2021; https://pubmed.ncbi.nlm.nih.gov/30127642/

How to use Lynparza 150mg Tablet:

Take Lynparza 150mg Tablet in a dose and duration prescribed by your doctor. Swallow the tablets whole with water. Do not crush or chew the tablets. You should not drink grapefruit juice or eat grapefruits during the treatment.

Safety advice:

Pregnancy:

Lynparza 150mg Tablet should not be taken during pregnancy as it can harm the baby. You need to tell your physician if you are pregnant or planning to get pregnant before taking this medicine. 

Breastfeeding:

Do not breastfeed while taking Lynparza 150mg Tablet and for at least one month after the last dose. You need to tell your physician if you are breastfeeding before taking this medicine. 

Kidney:

You need to tell your physician if you have any kidney disorders before taking Lynparza 150mg Tablet, as this medication should be used with caution in kidney disease patients.

Driving: 

Lynparza 150mg Tablet may cause dizziness or tiredness. Avoid driving if you are unwell.

Others:

• Before taking Lynparza 150mg Tablet, talk to your physician if you have lung disorders, allergic conditions, or other diseases.

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. The Lynparza side effects are:

Serious:

• Anemia (Shortness of breath, fast heartbeat, pale skin, feeling very tired)

Common:

• Nausea, vomiting
• Indigestion or heartburn
• Loss of appetite
• Changes in taste
• Cough
• Dizziness, headache
• Diarrhea