MADOPAR 250MG TABLET

Introduction:

Madopar 250mg Tablet is a combination medication containing the active constituents levodopa and benserazide hydrochloride. It is used to treat Parkinson’s disease. People with Parkinson’s disorder lack enough chemical substance called dopamine in some parts of their brains, and this can lead to tremors, stiff muscles, and slow movements. 

Before taking Madopar 250mg Tablet, you need to inform your physician if you have eye diseases, heart problems, kidney diseases, liver diseases, mental health problems, ulcers, diabetes, or have ever had skin cancer. If you are going to have an operation, inform your doctor that you are taking this medication.

Make sure you inform the physician of all the medications, including herbal medications and supplements, you are taking before you start treatment with Madopar 250mg Tablet. Use effective birth control during the treatment.

Uses of Madopar 250mg Tablet:

• Treatment of Parkinson’s disease

How Madopar 250mg Tablet works:

Dopamine transmits messages between parts of the brain and nerves that control movement. In the body, levodopa gets converted into dopamine and compensate for the depleted levels of dopamine. Benserazide allows more levodopa to enter the brain by preventing its breakdown in other body parts. This increases dopamine levels in the brain.

Interactions with other drugs:

Inform your doctor about any medications you are taking or have taken before the treatment.

More information:

• Keep Madopar 250mg Tablet out of sight and reach of children. 
• Do not store above 25°C.

References:

1. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Treatment of central nervous system degenerative disorders, and cytokines, 12th edition, 2011, 614-619.
2. KD Tripathi, Essentials of Medical Pharmacology, Antiparkinsonian drugs, 7th edition, 2013, 425-435.
3. Roche Products Limited, Electronic medicines compendium (emc), [ Revised on May 2019] [ Accessed on 12th Jan 2022], https://www.medicines.org.uk/emc/files/pil.6926.pdf   

How to use Madopar 250mg Tablet:

Always take Madopar 250mg Tablet exactly as your doctor has told you. Swallow the capsules whole with little water. Do not chew or crush the tablets. Take them thirty minutes before or one hour after meals.

Safety advice:

Pregnancy:

Madopar 250mg Tablet is not recommended for pregnant patients. You need to inform your doctor if you are pregnant or planning to get pregnant before taking this medicine.

Breastfeeding:

Madopar 250mg Tablet is not recommended for breastfeeding patients. Inform your doctor if you are breastfeeding before taking this medicine.

Liver:

You need to tell your physician if you have any liver disorders before taking Madopar 250mg Tablet, as this medication is contraindicated in patients with serious liver disorders.

Kidney:

You need to tell your physician if you have any kidney disorders before taking Madopar 250mg Tablet, as this medication is contraindicated in patients with serious kidney disorders.

Driving: 

Madopar 250mg Tablet can make you feel very sleepy. Avoid driving if you are unwell.

Others:

• Inform your physician if you have eye diseases, heart problems, mental health problems, ulcers, diabetes, or have ever had skin cancer.
• If you are going to have an operation, inform your doctor that you are taking this medication.

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.

Serious:

• Allergic reactions (itching, rash)
• Uneven heartbeat
• Bleeding in the stomach or intestines (black and tarry stools)
• Low blood cell counts

Common:

• Nausea, vomiting
• Headache, dizziness
• Dryness in the mouth
• Anxiety
• Constipation
• Abnormal dreams
• Feeling sleepy