MINIRIN 0.2MG TABLET

Introduction:

Minirin 0.2 mg Tablet contains desmopressin acetate as an active constituent. It is the synthetic form of vasopressin and it mimics the functions of vasopressin, a hormone that regulates the amount of urine produced in the kidneys. Minirin 0.2 mg Tablet is used for the treatment of diabetes insipidus in adults and bedwetting in children during nighttime.

Diabetes insipidus is referred to as water diabetes because it is a condition that causes the overproduction of urine. People with diabetes insipidus often experience polyuria (excessive urination) and polydipsia (excess intake of water due to thirst).

Follow a strict fluid restriction while taking a Minirin 0.2 mg Tablet to avoid the risk of hyponatremia (elevated sodium levels).it is advised to reduce the consumption of water by at least an hour before the intake of the medicine. For elderly patients, it is necessary to monitor renal function tests while taking this medicine to prevent renal impairment. Talk to your physician if you have a history of allergy, kidney, or heart diseases before taking Minirin 0.2mg Tablet. Also, inform your physician if you are taking any other medications to avoid drug-drug interactions. 

Uses of Minirin 0.2 mg Tablet:

• Diabetes insipidus
• Primary Nocturnal enuresis or Bedwetting in children
• Post removal of the pituitary gland-

How Minirin 0.2 mg Tablet works:

Minirin 0.2 mg Tablet produces its antidiuretic action by stimulating the vasopressin 2 receptors. Thereby, decreases urine production by increasing the water reabsorption in the kidneys. 

Interactions with other drugs:

Inform your doctor about any medications you are taking or have taken before the treatment.

More information:

• Keep Minirin 0.2 mg Tablet out of sight and reach of children.
• Store it at a controlled room temperature not exceeding 25°c. Avoid exposure to excess light or heat

References:

1. Ferring Pharmaceuticals, Electronic medicines compendium (EMC), [Revised on June 2011] [ Accessed on 25th April 2022], https://www.medicines.org.uk/emc/files/pil.3795.pdf
2. Ferring Pharmaceuticals, US Food and Drug Administration, [Revised on October 2019 ], [Accessed on 25th April 2022]; https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/021795s006lbl.pdf
3. Achinger SG, Ayus JC. Use of desmopressin in hyponatremia: foe and friend. Kidney Medicine. 2019 Mar 1;1(2):65-70. https://www.kidneymedicinejournal.org/action/showPdf?pii=S2590-0595%2819%2930023-8

How to use Minirin 0.2 mg Tablet:

Minirin 0.2 mg tablet is indicated for oral use only. Swallow the tablets whole with water. Do not crush or chew the tablets. Do not consume this medicine more than the prescribed dose in 24 hours.

Safety advice:

Pregnancy:

You need to inform your physician if you are pregnant or planning for a  pregnancy, before taking this medicine as Minirin 0.2mg Tablet is associated with a high risk of pre-eclampsia. Pre-eclampsia is a condition that occurs in pregnant women that causes complications such as high blood pressure, fluid accumulation, and proteinuria.

Breastfeeding:

If you are breastfeeding, it is important to seek advice from your doctor before taking this medicine as it can pass into breast milk.

Kidney:

You need to inform your physician if you have any renal impairment before taking the Minirin 0.2 mg Tablet. 

Alcohol: 

It is recommended to avoid taking alcohol while you are on Minirin 0.2 mg Tablet. 

Allergies: 

Inform your doctor if you have a known history of allergy to Minirin 0.2 mg Tablet or to the components present in the tablet.

Others:

inform your doctor before starting this medicine if you have the following conditions -

• Lactose intolerance, as this tablet contains lactose monohydrate.
• Cardiac disorders or are taking any diuretic medications.
• Infection, fever, or fluid/electrolyte imbalance.

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.

Serious:

• Convulsion-Fits

Common:

• Chronic headache
• Confusion
• Dramatic weight gain
• Nausea, vomiting
• Skin rashes, itching all over the body like allergic skin reactions
• Wheezing, Chest tightness, shortness of breath
• Swelling of the ankle, face, lips, or throat
• Decrease in sodium levels(hyponatremia)
• Stomach pain
• Diarrhea or constipation
• Urinary retention
• Dehydration