MYCEPT SUSPENSION

Introduction:

Mycept Suspension consists of the active ingredient Mycophenolate mofetil. It is an immunosuppressant used to prevent and treat organ rejection in patients receiving allogenic, renal, cardiac, or hepatic transplants. It is indicated along with other immunosuppressants to avoid the rejection of the transplanted organ. 

Inform your physician right away if there is a sign of fever, sore throat, bleeding, stomach ulcer. Talk to your physician before getting vaccinated using live vaccines.

After solid organ transplantation, the body generates an aggressive immune response because it recognizes the transplanted organ's antigens as a foreign antigen. Thus, treatment with immunosuppressive agents is necessary after an organ transplant to prevent organ rejection.

Immunosuppressants increase the risk of skin cancer. Limit your exposure to the sun, wear protective clothing and use a sunscreen with high SPF.

Uses of Mycept Suspension:

• Prevention of organ rejection after organ transplantation (liver, kidney or heart)
• To prolong the survival of the transplanted organ.
• Prophylaxis and treatment of acute and chronic Graft versus Host disease in hematopoietic stem cell transplant patients.

How Mycept Suspension Works:

Mycept Suspension converts into its active form known as Mycophenolic acid and suppresses the production of T- and B-cells. This reduces the cell-mediated immune responses and antibody formation. 

Interaction with other drugs:

Inform your doctor about any medications you are taking or have taken before the treatment.

More Information:

Store the medicine below 25°C.

References:

1. Roche Products Limited, Electronic Medicines Compendium (EMC), [Revised on Feb 2020] [Accessed on 13th Jan 2022], https://www.medicines.org.uk/emc/files/pil.1569.pdf
2. S.E. Marshall, Immunological Factors in disease, Davidson’s Principles and Practice of Medicine, 22nd Edition, 2014, 71-96.
3. KD Tripathi, Immunosuppressant Drugs, Essentials of Medical Pharmacology, 8th Edition, 2019,.937-945.
4. Ahmed A. Negm & Daniel E. Furst, Nonsteroidal Anti-Inflammatory Drugs, Disease-Modifying Antirheumatic Drugs, Nonopioid Analgesics, & Drugs Used in Gout, Lange’s Basic & Clinical Pharmacology, 14th Edition, 2018, 642-666.

How to use Mycept Suspension: 

Use as directed by your physician. Your physician will prescribe a dose depending upon the type of organ transplant performed (heart, liver or kidney). 

Safety Advice:

Pregnancy:

This medicine could harm the fetus and cause birth defects when taken during pregnancy. Tell your physician before taking this medicine if you are pregnant or planning to have a baby. 

Breast feeding:

Breastfeeding during this treatment is not recommended. Hence, discuss with your physician before taking this medicine if you are breastfeeding or planning to breastfeed your baby.

Driving: 

If you feel drowsy, numb or confused, talk to your doctor and do not drive or use any tools or machines until you feel better.

Others:

• Do not donate blood for at least 6 weeks after the last dose of Mycept Suspension.
• Inform your physician if you have stomach ulcers
• Use an effective method of contraception while on treatment with Mycept Suspension.
• Your physician will regularly conduct blood tests to check for changes in your blood cells and detect signs of infections.
• Inform your physician in case you experience allergic reactions to Mycept Suspension or its ingredients.

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

Serious:

• Infections, fever or sore throat
• Unusual bleeding or bruising
• Severe allergic reactions
• Lung problems

Common:

• Higher risk of developing lymphoma and other cancers
• High risk of developing infections
• Nausea, abdominal pain
• Diarrhea
• Anaemia
• Blood in urine
• Skin problems
• Constipation
• Mouth ulcers
• Inflammation of the pancreas, colon or stomach
• Indigestion
• Loss of appetite
• Dizziness
• Drowsiness
• Tremor
• Muscle spasms
• Changes in heartbeat, blood pressure
• Sinus problems
• Weight loss