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Neoprate Injection
Last updated on 31 Mar 2026 | 09:31 AM (IST)
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Introduction to Neoprate Injection
Neoprate Injection is an anticonvulsant medication that belongs to a class of drugs known as sodium channel modulators containing the active ingredient Sodium valproate. It is used to treat epilepsy, including various seizure types and epilepsy syndromes. Epilepsy is a neurological disorder caused by recurrent and unpredictable seizures. Seizures are episodes of abnormal electrical activity in the brain that can lead to a wide range of symptoms, including loss of consciousness, muscle spasms, convulsions, altered sensations, or changes in behavior. It can also be prescribed for neurological conditions like bipolar disorder and migraines.
Do not use Neoprate Injection if you are allergic to Sodium valproate or any of the other ingredients of this medicine. Individuals with a rare condition called porphyria, which affects the breakdown of components of red blood cells, have a history of severe liver problems, urea cycle disorder, or mitochondrial disorder, such as Alpers-Huttenlocher syndrome. This medication should be avoided.
Before initiating the treatment, notify your physician if you have diabetes, kidney problems, brain disease, systemic lupus erythematosus, or a carnitine palmitoyltransferase type II deficiency. In these cases, discussing your medical history and conditions with your physician is necessary to ensure the safe and effective use of this injection. If you are a woman who can become pregnant and are taking Neoprate Injection, use an effective method of birth control throughout your entire treatment with this medication.
Uses of Neoprate Injection
- Treatment of epilepsy/seizures
Therapeutic Effects of Neoprate Injection
Neoprate Injection works by increasing the neurotransmitter levels called gamma-aminobutyric acid (GABA) in the brain. GABA helps to calm nerve activity and reduce the likelihood of seizures or mood swings.
Interaction of Neoprate Injection with other drugs
Inform your healthcare provider about all your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications such as warfarin, zidovudine, temozolamide, selegiline, and propofol may interact with Neoprate Injection and reduce their effectiveness by causing undesirable side effects.
More Information about Neoprate Injection
- Store Neoprate Injection at a controlled room temperature between (15°C-30°C).
- Do not freeze
How to consume Neoprate Injection
Neoprate Injection will be given to you by a doctor or other healthcare professional. It will be given as an intravenous injection (into a vein). It can also be given as an infusion through a drip into a vein. Your healthcare provider will decide the dose, route of administration, and duration of the treatment based on your health condition and other factors. Do not self-administer the medicine.
Safety Advice for Neoprate Injection
Breast Feeding
Breastfeeding is not recommended in patients taking Neoprate Injection because the medicine passes into the breast milk in small amounts and may harm your baby. Do not breastfeed during the treatment.
Alcohol
Consuming alcohol during the treatment with Neoprate Injection is not recommeded. There can be any interactions and harmful side effects.
Liver
Neoprate Injection should be administered cautiously in patients with liver diseases. Dose adjustments are necessary if you have liver problems. Inform your physician if you have any liver disease before initiating the therapy.
Lungs
It is unknown whether Neoprate Injection can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.
Driving
When you are first given Neoprate Injection, you may experience drowsiness as a side effect. If you are affected by drowsiness, it is strongly advised not to drive or operate machinery.
Pregnancy
You should not use Neoprate Injection during pregnancy unless there are no other effective treatment options available. If you are pregnant, planning to become pregnant, or think you may be pregnant, it is essential to consult your doctor before taking the injection.
Side Effects of Neoprate Injection
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious
- Severe blistering rash
- Liver problems
- Blood clotting problems
- Changes in mood, loss of memory, lack of concentration
Common
- Diarrhea
- Stomach pain
- Nausea, vomiting
- Feeling dizzy or fainting
- Hearing problems
- Hair loss
- Changes in women’s periods
- Breast enlargement
- Swelling of feet and legs
- Weight gain
- Agitation
- Tingling or numbness in hands and feet
- Muscle pain and weakness
Word of Advice
Alcohol can interact with Neoprate Injection and potentially increase side effects like drowsiness. It's usually recommended to limit or avoid alcohol consumption while on this medication. Maintain a balanced diet and regular eating schedule. This medicine can affect appetite or cause weight gain, so it's important to discuss any dietary concerns with your doctor or a registered dietitian.
FAQs about Neoprate Injection
Q1.
What is the actual mechanism of action of Neoprate Injection?
Neoprate Injection works by increasing the levels of a neurotransmitter called gamma-aminobutyric acid (GABA) in the brain. GABA helps to calm nerve activity and reduce the likelihood of seizures or mood swings.
Q2.
Can Neoprate Injection be used in children?
Neoprate Injection can be prescribed to children, but the dosage and safety considerations may differ from those in adults. It should only be used in children under the supervision of a pediatrician or neurologist.
Q3.
Can I drink alcohol while taking Neoprate Injection?
It's advisable to avoid alcohol while taking Neoprate Injection, as alcohol can increase the risk of side effects such as drowsiness and liver problems.
Q4.
Is Neoprate Injection safe during pregnancy?
Neoprate Injection is generally not recommended during pregnancy unless there are no other effective treatment options available. Pregnant women should discuss alternative treatment options with their physicians.
Q5.
What are the common side effects of Neoprate Injection?
The common side effects of Neoprate Injection may include drowsiness, dizziness, weight gain, nausea, and hair thinning. However, side effects can vary from person to person.
Fact Box of Neoprate Injection
| Molecule Name: Sodium valproate | Therapeutic Class: Anti-convulsants |
| Pharmacological Class: Sodium channel modulators | Indications: Treatment of epilepsy/seizures |
References
- Desitin Arzneimittel GmbH, Electronic medicines compendium (EMC), [Revised on Dec 2021] [ Accessed on 02 Sep 2023], https://www.medicines.org.uk/emc/files/pil.293.pdf
- Hospira, Inc, US Food and Drug Administration, [Revised on July 2013] [ Accessed on 02 Sep 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/020593s026lbl.pdf
- KD Tripathi, Essentials of Medical Pharmacology, Antiepileptic drugs, 7th edition, 2013, 417.
Disclaimer
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Author Details
Written By
Dr. B. Deiva
Pharm D
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 31 Mar 2026 | 09:31 AM (IST)
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