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Nerivio Remote Electrical Neuromodulation Device for Migraine_203437
Nerivio Remote Electrical Neuromodulation Device for Migraine_203437
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Nerivio Remote Electrical Neuromodulation Device for Migraine

Prescription Required

Salt Composition : Device

Manufacturer : DR REDDY'S LABORATORIES LTD

Origin of Medicine : Israel

MRP: 16000
Price : 12800
You Save : 3200 (20%)

1 Device(s)

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Introduction to Nerivio Remote Electrical Neuromodulation Device For Migraine

Nerivio Remote Electrical Neuromodulation (REN) Device is a non-invasive, FDA-approved therapy designed for the acute treatment of migraine in individuals aged 12 years and older. This device uses remote electrical stimulation applied to the upper arm to modulate pain signals and relieve migraine attacks effectively. It is a user-friendly, wireless device controlled through a smartphone app, making it convenient for at-home use.

The active mechanism involves neuromodulation through electrical pulses that stimulate the body's Conditioned Pain Modulation (CPM) system. Nerivio provides pain relief by triggering the release of serotonin and norepinephrine, two neurotransmitters that play a key role in reducing headache severity. While generally safe, Nerivio should not be used by individuals with implanted medical devices, severe heart conditions, or epilepsy. Pregnant or breastfeeding women should consult their doctor before using this device.


Uses of Nerivio Remote Electrical Neuromodulation Device For Migraine

Nerivio is approved for the following uses:

  • Acute treatment of migraine with or without aura in patients aged 12 years and above.
  • Can be used for episodic and chronic migraine management.

Therapeutic Effects of Nerivio Remote Electrical Neuromodulation Device For Migraine

Nerivio works by delivering electrical pulses to the C-fiber nerves in the upper arm, which transmit signals to the brainstem. This process activates the brain’s Conditioned Pain Modulation (CPM) mechanism, leading to the release of pain-inhibiting chemicals such as serotonin and norepinephrine. These neurotransmitters reduce pain perception and alleviate migraine symptoms effectively.

By modulating pain at the source and promoting natural pain-relief mechanisms, Nerivio helps manage both the intensity and duration of migraine attacks without the need for pharmaceutical interventions.


Interaction of Nerivio Remote Electrical Neuromodulation Device For Migraine with other drugs

Nerivio should not be used in the following conditions due to potential safety risks:

  • Cardiac and Cerebrovascular Conditions: Patients with severe cardiac disorders, cerebrovascular disease, or congestive heart failure should avoid using this device as electrical stimulation may interfere with heart rhythm.
  • Epilepsy and Seizure Disorders: Patients with a history of epilepsy or seizure disorders should not use Nerivio, as electrical neuromodulation may trigger seizures.
  • Implantable Medical Devices: Individuals using pacemakers, hearing aids, cochlear implants, or any other electronic or implantable medical device should avoid Nerivio to prevent device interference.
  • Pregnancy and Breastfeeding: Safety data is limited, and patients should consult a doctor before using Nerivio during pregnancy or lactation.

More Information about Nerivio Remote Electrical Neuromodulation Device For Migraine

  • Store the device in a cool, dry place away from direct sunlight.
  • Since this is a device-based therapy, missed doses do not apply. However, it is best to use the device as prescribed.
  • Do not extend therapy sessions beyond 45 minutes without medical consultation. Overuse may result in increased skin irritation or discomfort.
  • Ensure the device is charged and properly maintained between uses.

How to consume Nerivio Remote Electrical Neuromodulation Device For Migraine

To use the Nerivio device effectively, place it on the upper arm of the non-dominant side (opposite hand to the one you write with) and secure it properly. Activate the device using the companion smartphone app, which allows you to control the intensity and duration of the session. For acute migraine attacks, use the device within 60 minutes of headache onset, with a standard session lasting 45 minutes. For preventive treatment, use the device for 45 minutes every alternate day. Always follow the instructions provided in the user manual and consult your doctor before adjusting the duration or frequency of sessions.


Safety Advices for Nerivio Remote Electrical Neuromodulation Device For Migraine

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Pregnancy

  

There is limited data on the safety of Nerivio during pregnancy. It is recommended to consult a healthcare provider before using the device if you are pregnant.

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Breast Feeding

  

The effects of Nerivio on breastfeeding mothers and infants are unknown. It is advisable to inform your doctor before starting the treatment.

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Lungs

  

No established data is available on the use of Nerivio in individuals with chronic lung diseases. Inform your doctor if you have any respiratory issues before use.

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Liver

  

There is no conclusive data on the safety of using Nerivio in patients with chronic liver disease. It is best to consult your doctor before using the device.

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Alcohol

  

The interaction of Nerivio with alcohol consumption is not well studied. Avoid excessive alcohol consumption while using this device.

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Driving

  

Nerivio does not impair driving abilities. However, avoid using the device while driving or operating heavy machinery.


Side Effects of Nerivio Remote Electrical Neuromodulation Device For Migraine

Common side effects:

  • Mild skin irritation or redness at the application site.
  • Tingling or numbness in the arm during or after use.

Serious side effects:

  • Severe skin irritation or allergic reaction.
  • Electrical sensitivity or increased discomfort during use.

Word of Advice

Patients with a history of heart conditions, epilepsy, or implantable devices should avoid using Nerivio. It is essential to follow the prescribed usage duration to prevent any discomfort or adverse effects. Do not extend the therapy beyond 45 minutes without medical supervision. Ensure the device is properly charged and maintained for consistent performance. Seek immediate medical advice if you experience any severe skin reactions or unusual sensations during use.


FAQs

Q 1. What is Nerivio used for?

Nerivio is a remote electrical neuromodulation device used for the acute treatment of migraine with or without aura in patients aged 12 years and older. It provides a non-pharmaceutical option for managing migraine pain.

Q 2. How does Nerivio help relieve migraine pain?

Nerivio stimulates the nerves in the upper arm, which sends signals to the brainstem to activate the Conditioned Pain Modulation (CPM) system. This process releases serotonin and norepinephrine, reducing pain and alleviating migraine symptoms.

Q 3. Can I use Nerivio for preventing migraines?

Yes, Nerivio can be used as a preventive treatment for migraines. It is recommended to use the device for 45 minutes every alternate day to reduce the frequency and severity of migraine attacks.

Q 4. Is Nerivio safe for people with heart conditions?

No, individuals with severe cardiac disorders, pacemakers, or implantable devices should avoid using Nerivio. It may interfere with the functioning of such devices, posing a safety risk.

Q 5. Can pregnant or breastfeeding women use Nerivio?

There is limited information on the safety of Nerivio during pregnancy and breastfeeding. It is best to consult a healthcare provider before using the device during these conditions.


Fact Box of Nerivio Remote Electrical Neuromodulation Device For Migraine

Molecule name: N/A (Device Based Therapy)

 

Pharmacological class: Neuromodulation device

Therapeutic Class: Non-Pharmaceutical Migraine Management

 

Indications: 

Acute treatment of migraine with or without aura in patients aged 12 years and older


References

  1. Nierenburg, H., & Stark-Inbar, A. (2021). Nerivio® remote electrical neuromodulation for acute treatment of chronic migraine. Pain Management, 12(3), 267-281.
  2. Product Highlight Nerivio (Accessed 6 June 2024) https://dtxalliance.org/products/nerivio/ 

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