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OPDYTA 40MG INJECTION_1
OPDYTA 40MG INJECTION_2
OPDYTA 40MG INJECTION_1
8% Off

Opdyta 40mg Injection

Prescription Required

cold-chain

Salt Composition : Nivolumab

Manufacturer : BRISTOL MYERS SQUIBB

Origin of Medicine : United States of America

MRP: 39800
Price : 36616
You Save : 3184 (8%)

1 Vial(s) Of 4ml

Prepaid Only. Non-Returnable

Pincode
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Patient Assistance Programs
Know About PAP

Program Overview:  BRISTOL MYERS SQUIBB Limited, is dedicated to helping patients in need of Opdyta 40mg injection. The program aims to provide eligible patients with access to the medication at a more affordable cost.

Program Benefits:  Get proper guidance from us in getting financial assistance directly from Bristol Myers Squibb Ltd. to cover your cost of medicines or get free medicines for the eligible patient with patient assistance programs (PAP). We encourage you to contact us for the latest updates on this exclusive offer. 

Eligibility Criteria: To qualify for Bristol Myers Squibb’s Patient Assistance Program (PAP), you must meet specific criteria, including having a valid prescription for nivolumab 40mg injection from a medical oncologist and being an Indian patient with a valid identity card. Eligibility is determined based on the diagnosed condition and program-specific requirements.

Contact Information: If you have any questions or need assistance with the application process, our dedicated patient support team is here to help. You can reach us by phone at 89391 69999 or email us at [email protected].

Please note that MrMed is not involved in the PAP program. They offer free consultations to patients to provide information about the program. Patients eligible for the PAP program by Pfizer can avail of it without having to purchase the medication from MrMed. 

Introduction to Opdyta 40mg Injection

Opdyta 40mg Injection consists of the active substance Nivolumab. It is indicated to treat cancers of the skin, lungs, kidney, lymph node, bladder, esophagus, and urinary tract. This medicine is indicated when the cancer has recurred after treatment using medicines, surgery, and radiation. It is a medication that helps the immune system fight cancer more effectively. It works by targeting and inhibiting specific molecules that can suppress or weaken the immune system's ability to recognize and attack cancer cells. By blocking these molecules, it helps to enhance the immune response against cancer and potentially shrink or slow the growth of tumors. 

 

One of the benefits of it and other immunotherapy drugs is that they can produce long-lasting responses in some patients, even after the treatment is stopped. This contrasts traditional chemotherapy and radiation therapy, which typically only provide temporary benefits and can have significant side effects. It is contraindicated in patients with a severe allergic reaction to the drug or its components. It is also contraindicated in patients with certain autoimmune disorders, such as lupus or rheumatoid arthritis because the drug can further stimulate the immune system and exacerbate these conditions. Additionally, it should be used cautiously in patients with a history of organ transplants.


Uses of Opdyta 40mg Injection

  • Advanced skin cancer
  • Skin cancer that recurs after surgery
  • Advanced non-small cell lung cancer
  • Advanced kidney cancer
  • Hodgkin’s lymphoma (lymph node disease)
  • Advanced cancer of the head and neck
  • Advanced urinary tract and bladder cancer
  • Advanced esophageal cancer

Therapeutic Effects of Opdyta 40mg Injection

The therapeutic effect of Opdyta 40mg Injection is to enhance the body's natural immune response to cancer cells. Cancer cells can often evade the immune system by producing proteins that bind to immune cells and prevent them from recognizing and attacking the cancer cells. It works by blocking the interaction between a protein called programmed death-1 (PD-1), found on the surface of immune cells, and its corresponding ligands. Doing so enables the immune system to recognize and attack cancer cells more effectively, helping to slow down or even stop cancer progression. In some cases, treatment with it can lead to long-lasting remission, even after treatment has ended. This is because the drug can stimulate the immune system to "remember" the cancer cells and continue to attack them even after the drug has been cleared from the body.


Interaction of Opdyta 40mg Injection with other drugs

Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Opdyta 40mg Injection and reduce effectiveness by causing undesirable side effects.


More Information about Opdyta 40mg Injection

  • Opdyta 40mg Injection is typically supplied in vials or pre-filled syringes and should be stored at controlled room temperature between 20-25°C (68-77°F).
  • The drug should be protected from light and should not be frozen.
  • Once the vial or syringe is opened, any unused portion should be discarded. It is important to follow the manufacturer's instructions for handling and storage of it to ensure that the drug is effective and safe for use.
  • Keep it out of reach from children and pets.

How to consume Opdyta 40mg Injection

Opdyta 40mg Injection is a medication a healthcare professional administers, typically in a hospital or clinic setting. The medication is given as an intravenous (IV) injection by healthcare professional. The infusion typically takes several hours. You will be closely monitored during and after the infusion to ensure the medication works effectively and to watch for any side effects. The dosage and frequency of administration will depend on the condition being treated and your circumstances. Your healthcare provider will determine the appropriate dosage and schedule for you.


Safety Advices for Opdyta 40mg Injection

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Pregnancy

  

Opdyta 40mg Injection is unsafe for a developing foetus and is not recommended during pregnancy as it can cause harm to the developing foetus.

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Breast Feeding

  

It is unknown whether Opdyta 40mg Injection is excreted in human breast milk, so breastfeeding women should discuss the potential risks and benefits of the medication with their healthcare provider before starting treatment.

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Lungs

  

Opdyta 40mg Injection should be used cautiously in individuals with lung disease, as the medication can potentially worsen lung function. Your healthcare provider will monitor you closely if you have lung disease and adjust your dosage if necessary. If you have lung disease or a history of respiratory problems, discussing the potential risks and benefits of the injection treatment with your healthcare provider is important. Your healthcare provider may recommend additional monitoring or testing to ensure the medication is not causing any adverse effects on your lungs.

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Liver

  

Opdyta 40mg Injection should be used cautiously in individuals with liver disease, as the medication is primarily metabolized in the liver and could potentially worsen liver function. Your healthcare provider will monitor you closely if you have liver disease and adjust your dosage if necessary. 

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Alcohol

  

There are no known interactions between Opdyta 40mg Injection and alcohol. However, it is generally recommended to avoid consuming alcohol while being treated for a medical condition, as alcohol can potentially interfere with the effectiveness of the medication and increase the risk of side effects.

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Driving

  

Patients receiving Opdyta 40mg Injection should be advised to avoid driving or operating machinery if they experience side effects such as fatigue, dizziness, or blurred vision, impairing a patient's ability to drive or operate machinery safely.


Side Effects of Opdyta 40mg Injection

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

Serious:

  • Pneumonitis (inflammation of lung tissue)
  • Colitis (inflammation of the colon)
  • Hepatitis (inflammation of the liver)
  • Hypothyroidism
  • Hyperthyroidism
  • Adrenal insufficiency (a condition in which the adrenal glands do not produce enough hormones).
  • Severe allergic reactions
  • Infusion-related reactions
  • Confusion
  • Seizures
  • Neuropathy
  • Eye disorders (such as uveitis or iritis)

Common:

  • Fatigue
  • Nausea
  • Skin rash
  • Itching
  • Loss of appetite
  • Diarrhea
  • Constipation
  • Joint pain
  • Headache

Word of Advice

If you are considering or receiving Opdyta 40mg Injection treatment, it is important to discuss the potential risks and benefits of the treatment with your healthcare provider. It is also important to follow all safety precautions and guidelines provided by your healthcare provider to minimize any potential risks associated with treatment. Be sure to report any new or worsening symptoms to your healthcare provider promptly, as some side effects can be serious and require immediate medical attention. If you are a women of reproductive age, you should use effective contraception during and for at least 5 months after the last dose of it to avoid potential harm to a developing fetus. Remember to take care of yourself and prioritise self-care during treatment. This can include eating a healthy diet, getting enough rest, and seeking support from loved ones or support groups.


FAQs

Q 1. Can Opdyta 40mg Injection Cause Skin Reactions?

Some patients receiving Opdyta 40mg Injection may experience skin reactions such as rash, itching, or blistering. These side effects should be reported to a healthcare provider as they may require treatment.

Q 2. Can Opdyta 40mg Injection Cause Infertility?

There is limited data on the long-term effects of Opdyta 40mg Injection on fertility. However, the medication may impact fertility in some patients, particularly those receiving high doses or long-term treatment. Patients concerned about their fertility should discuss their options with a healthcare provider.

Q 3. Can Opdyta 40mg Injection Cause Diabetes?

Opdyta 40mg Injection may cause changes in blood sugar levels, leading to diabetes in some patients. Patients should be monitored closely for changes in their blood sugar levels during treatment.

Q 4. Can Opdyta 40mg Injection be Used in Children?

Opdyta 40mg Injection is not currently approved for use in children. However, some clinical trials are underway to evaluate the safety and effectiveness of the medication in pediatric patients.

Q 5. How Does Opdyta 40mg Injection Compare to other Immunotherapy medications?

Opdyta 40mg Injection is one of several immunotherapy medications that are used to treat cancer. The specific medication used may depend on several factors, including the type and stage of the cancer being treated and the patient's response to treatment. Patients should discuss their options with a healthcare provider to determine the best treatment plan for their situation.

Q 6. How Is Opdyta 40mg Injection Different from Chemotherapy?

Opdyta 40mg Injection is an immunotherapy that enhances the body's natural immune response to cancer cells. Chemotherapy, on the other hand, works by killing cancer cells directly. While both treatments may be used in combination for some types of cancer, they work in different ways and may have different side effects.

Q 7. How Often Are Patients Monitored During Opdyta 40mg Injection Treatment?

Patients receiving Opdyta 40mg Injection treatment will typically be monitored closely for any signs of adverse reactions or changes in their cancer status. This may include regular blood tests, imaging studies, and physical exams.


Fact Box of Opdyta 40mg Injection

Molecule name: Nivolumab

 

Therapeutic class: Anticancer

Pharmacological class: Monoclonal antibody

Indications: 

1.Advanced skin cancer

2.Skin cancer that recurs after surgery

3.Advanced non-small cell lung cancer

4.Advanced kidney cancer

5.Hodgkin’s lymphoma (lymph node disease)

6.Advanced cancer of the head and neck

7.Advanced urinary tract and bladder cancer

8.Advanced esophageal cancer


References

  1. Harrison's Principles of Internal Medicine. 20th edition, 2018, 929-932
  2. Bristol-Myers Squibb, U.S. Food and Drug Administration, Nivolumab, [ Last updated, 4 April 2023]. [ Accessed on 4 April] https://www.accessdata.fda.gov/drugsatfda_docs/label/2022/125554s114lbl.pdf.
  3. Goodman & Gilman's The Pharmacological Basis of Therapeutics. 12th edition, 2011,1655-1660
  4. Takeda UK Ltd, Electronic Medicines Compendium (emc), Opdivo 10 mg/mL concentrate for solution for infusion, [Last updated: 30 October 2020], [Accessed on 4 April 2023], https://www.medicines.org.uk/emc/product/6154/smpc

Disclaimer

MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.