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Treatment of hormone receptor (HR)-positive, human epidermal growth factor 2 (HER2)-negative advanced or metastatic breast cancer.

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Palbace 75mg Tablet works by blocking the protein called cyclin-dependent kinases 4 and 6, which are vital for the division and growth of cells. By blocking these proteins, this medication slows the growth and prevents the cancer cells from spreading.

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Inform your doctor about all medications including prescribed, over-the-counter, nutritional or vitamin supplements and herbal products that you are taking or have taken before the treatment. Concurrent use of palbociclib with CYP3A4 inhibitors such as fentanyl has reported increased fentanyl toxicity. certain medications may interact with the effectiveness of this drug.

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Keep Palbace 75mg Tablet out of sight and reach of children.
Store at 20°C to 25°C

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Take Palbace 75mg Tablet exactly as prescribed by your doctor. Take this medication once a day at the same time with food. Swallow this capsule as a whole with a glass of water. Avoid crushing, breaking, or chewing the capsule.

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It is not recommended to take Palbace 75mg tablet while breastfeeding as it is not known whether it passes into the breast milk.

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It is unknown whether it is safe to drink alcohol while taking Palbace 75 mg. Check with your doctor for advice.

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Inform your physician if you have any liver disorders before taking Palbace 75 mg, as it should be used with caution in liver disorder patients.

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Palbace 75mg tablet can cause tiredness. Avoid driving if you are unwell.

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It is not recommended to take Palbace 75mg tablet during pregnancy as it can harm the unborn baby. Women with childbearing potential should use effective contraceptives during treatment and for at least three weeks after treatment.

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Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.

Serious:

Blood disorder (fever, chills, shortness of breath, weakness, bleeding, or bruising)
Lung inflammation (chest pain, dry cough, or difficulty breathing)

Common:

Tiredness
Hair loss
Dry skin, rash
Infections
Low blood cell counts
Decreased of appetite
Nausea, vomiting
Diarrhea
Swelling of lips and mouth
Changes in taste
Nose bleed
Dry eye, blurred vision, increased tearing

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During Palbace 75mg treatment, it is advised to avoid grapefruit and its juices and preparations containing St. John's wort. It is recommended to use effective birth control while receiving treatment as well as for at least three weeks after the final dose for females and at least fourteen weeks after the final dose for males. This medication may reduce fertility, so discuss with the physician if you have any concerns. Your doctor may recommend regular blood tests to determine whether Palbace 75mg tablet affects your blood cells.

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Is Palbace 75mg Tablet targeted therapy?

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Yes, Palbace 75mg Tablet is a targeted therapy. This medication belongs to the class of cyclin-dependent kinase inhibitors.

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Can children use Palbace 75 mg?

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No, Palbace 75mg tablet is not recommended for adolescents and children under 18.

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Does Palbace 75mg Tablet affect fertility?

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Yes, Palbace 75mg Tablet may reduce fertility in men. It may affect your ability to become a father and a child. Hence, men should consider sperm preservation before taking this medication.

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Molecule name	Palbociclib
Therapeutic class	Cyclin-dependent kinase inhibitor
Pharmacological class	Anticancer agents
Indications	HR-positive, HER2-negative advanced or metastatic breast cancer

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Pfizer Labs, US Food and Drug Administration, [Revised on March 2017] [ Accessed on 26 Nov 2022], https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/207103s004lbl.pdf
Neha S Mangini et al; Palbociclib: A Novel Cyclin-Dependent Kinase Inhibitor for Hormone Receptor-Positive Advanced Breast Cancer; The Annals of Pharmacotherapy; Published on Nov 2015; Accessed on 26/11/2022; https://pubmed.ncbi.nlm.nih.gov/26324355/
Palbace; Pfizer; Revised on Oct 2021; Accessed on 26/11/2022; https://labeling.pfizer.com/ShowLabeling.aspx?id=14029

"}},{"id":"b8b8b919-b824-47e5-8b9b-e74a7de14f40","type":"DISCLAIMER","position":13,"content_placement":5,"data":{"heading":"Disclaimer","text":"

MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.

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