PIVIKTO 200MG TABLET
ALPELISIB
Manufacturer : NOVARTIS INDIA LTDOrigin of Medicine : SwitzerlandBuy 18 strips, get 25 strips Free. Contact us for latest updates.
Buy 18 strips, get 25 strips Free. Contact us for latest updates.
Introduction:
Pivikto 200mg Tablet consists of the active ingredient Alpelisib. It effectively treats advanced breast cancer that occurs in men and postmenopausal women. This medicine is specifically active against the type of breast cancer cells called advanced hormone receptor (HR)-positive, human epidermal growth factor receptor 2
(HER2)-negative breast cancer.
Your physician will test a sample of blood or tumor tissue to check for the presence of PI3K mutations. A positive result shows that you are likely to respond to this treatment.
Pivikto 200mg Tablet uses:
- Treatment of advanced breast cancer.
- Adjunct to other hormonal anti cancer therapies for patients who have not responded adequately to other anti cancer treatments.
How Pivikto 200mg Tablet Works:
Phosphatidylinositol 3-kinase (PI3K) enzyme is essential for the survival of cancer cells. When these proteins undergo changes, it makes the cancer cells more aggressive and resists HER2- targeted medicines. Alpelisib Pivikto 200mg Tablet works by blocking the effect of PI3K enzymes. It targets and inhibits the growth and spread of cancer cells.
Interaction with other drugs:
Inform your doctor about any medications you are taking or have taken before the treatment.
More Information:
Keep the tablets away from sight and reach of children. Do not store above 30ËšC.
References:
- Kui-Jin Kim, et al., PI3K-targeting strategy using alpelisib to enhance the antitumor effect of paclitaxel in human gastric cancer, Scientific Reports, Jul 2020, [Accessed on 1st Apr 2021] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7378194
- Novartis Pharmaceuticals, Electronic Medicines Compendium(EMC) [Revised on May 2021] [Accessed on 27th Nov 2021] https://www.medicines.org.uk/emc/files/pil.11684.pdf
How to use Pivikto 200mg Tablet:
Use 200 mg Pivikto Tablets as recommended by your physician. Swallow the whole tablet, do not crush, chew or split the tablets before intake.
Safety Advice:
Pregnancy:
This medicine is not intended for use during pregnancy. Talk to your physician before you take this medicine if you are pregnant or think you might be pregnant.
Breastfeeding:
Consult your physician before taking this medicine if you are a breastfeeding mother.
Kidney:
This medicine should be taken with caution in patients with severe kidney impairment. Your physician might alter the dose while prescribing this medicine for you.
Driving:
This medicine may cause tiredness. hence, it is advisable to practice caution while driving or using machines.
Allergies:
Inform your physician if you have or ever had severe skin allergies, before initiating treatment with Alpelisib.
Others:
- Male patients who have female partners of reproductive age should use an effective and reliable method of contraception while on this treatment.
- Discuss with your physician before you take this medicine if you have diabetes, bone problems or any other health issues.
- This tablet is not suitable for children and adolescents aged below 18 years.
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious:
- High blood sugar levels
- Fever, cough, runny nose, joint pain, night sweats
- Rashes, itching and hives
- Breathing problems
- Altered frequency and amounts of urination
- Swelling of legs, ankles and eyes, tiredness, confusion, nausea, seizure and chest pain
- Osteonecrosis, characterized by heaviness in the jaw, loose teeth, pain, and swelling of the jaw
Common:
- Spontaneous bleeding or bruising
- Strange taste in the mouth
- Mouth sores
- Stomach pain, indigestion
- Hair loss or thinning
- Low calcium and potassium levels in the blood
- Muscle pain
- Insomnia
- Blurry vision and dry eyes

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