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Pletoz 50mg Tablet
Last updated on 28 Sep 2026 | 07:16 AM (IST)
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Introduction to Pletoz 50mg Tablet
Pletoz 50mg Tablet contains an active component called Cilostazol. It is used to improve the symptoms of intermittent claudication, a condition characterized by pain, cramping, numbness, or weakness in the legs that occurs during exercise and is relieved by rest. This medication helps to widen the arteries that supply blood to the legs, thereby improving blood flow and reducing the symptoms of intermittent claudication. It helps to improve the symptoms and increase the distance that individuals with this condition can walk without experiencing pain or discomfort. It helps treat peripheral arterial disease (PAD) and reduce thrombosis risk.
Individuals who have a known hypersensitivity or allergy to Pletoz 50mg Tablet or any of its components should not take this medication. It should not be used in patients with congestive heart failure of any severity. It should not be used in patients with bleeding disorders or those at an increased risk of bleeding, as it can further increase the risk of bleeding due to its mechanism of action. It may affect heart rhythm, so it should be used cautiously in patients with certain pre-existing heart rhythm disorders.
Use Pletoz 50mg Tablet with caution in older adults, as they may be more susceptible to the medication's side effects. Close monitoring is recommended, especially for any signs of bleeding or heart-related issues. It has not been studied extensively in children, and its safety and efficacy in pediatric populations have not been established. Therefore, its use in children is generally not recommended.
Uses of Pletoz 50mg Tablet
Pletoz 50mg Tablet is used in the following:
- Intermittent Claudication
- Peripheral arterial disease (PAD)
- Thrombosis risk reduction.
Therapeutic Effects of Pletoz 50mg Tablet
Pletoz 50mg Tablet is a selective phosphodiesterase III (PDE3) inhibitor in various cells, mainly in platelets. Inhibiting PDE3 increases intracellular cAMP (cyclic adenosine monophosphate) levels in platelets and vascular smooth muscle cells. Increased cAMP levels lead to decreased intracellular calcium concentrations, inhibiting platelet aggregation and vasodilation. This dual antiplatelet and vasodilatory effect helps improve blood flow, reduce thrombus formation, and alleviate symptoms associated with peripheral arterial disease and intermittent claudication.
Interaction of Pletoz 50mg Tablet with other drugs
Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Pletoz 50mg Tablet, reducing effectiveness by causing undesirable side effects.
More Information about Pletoz 50mg Tablet
- Store at room temperature, between 20°C to 25°C
- Keep away from moisture, heat, and light.
- It should not be frozen.
- Keep away from children and pets.
How to consume Pletoz 50mg Tablet
Pletoz 50mg Tablet is administered orally in the form of tablets. It is taken orally with or without food, as directed by a healthcare professional. The recommended starting dosage and any necessary dose adjustments are determined based on the specific condition being treated and the patient's response to the medication.
Safety Advice for Pletoz 50mg Tablet
Breast Feeding
Whether Pletoz 50mg Tablet passes into breast milk is unknown. Therefore, it is advisable to consult your healthcare provider before taking it while breastfeeding.
Alcohol
There are no specific known interactions between alcohol and Pletoz 50mg Tablet. However, it is advisable to consult a healthcare professional regarding the consumption of alcohol while taking Pletoz 50mg Tablet, as alcohol use may exacerbate certain side effects of the medication.
Liver
If you have any lung disorders, informing your healthcare provider before starting Pletoz 50mg Tablet is important.
Lungs
Consult your healthcare provider if you have a history of lung conditions before using Pletoz 50mg Tablet.
Driving
Pletoz 50mg Tablet is not known to impair the ability to drive or operate machinery. However, consult your healthcare provider if you experience side effects such as dizziness, headache, or other side effects.
Pregnancy
It is advisable to discuss the risks and benefits with a healthcare provider before using Pletoz 50mg Tablet during pregnancy.
Side Effects of Pletoz 50mg Tablet
Pletoz 50mg Tablet causes some side effects like all medications, although not everyone will experience them.
Serious
- Mood and mental health
- Gastrointestinal disturbances
- Allergic reactions
Common
- Gastrointestinal effects
- Neurological effects
- Respiratory tract infections
- General symptoms
Word of Advice
Pletoz 50mg Tablet can increase the risk of bleeding, so it is important to be cautious if you have a bleeding disorder or are taking other blood-thinning medications. It may also affect your heart and cause palpitations, so be watchful if you have any heart conditions. People with liver or kidney problems should use it carefully and may need adjustments in their dosage. If you have had recent surgery or have known allergies to it or any other medications, make sure to inform your doctor. It can interact with other medications, so let your healthcare provider know about all the drugs you are taking. If you have heart failure, a bleeding disorder, or are older, consult your doctor before taking this medication.
It is a good idea to consult your healthcare provider about consuming alcohol while taking this medication. Always follow your doctor's advice, and if you experience any unusual symptoms, let your doctor know immediately.
FAQs about Pletoz 50mg Tablet
Q1.
How long does it take for Pletoz 50mg Tablet to work?
Pletoz 50mg Tablet's effects may vary from person to person. Some people may notice an improvement in their symptoms within a few weeks, while others may take longer. It is essential to follow the prescribed dosage and give it time to take effect.
Q2.
What should I do if I miss a dose of Pletoz 50mg Tablet?
If you miss a dose of Pletoz 50mg Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.
Q3.
What are the common side effects of Pletoz 50mg Tablet?
Common side effects of Pletoz 50mg Tablet may include headache, diarrhea, abnormal stools, and palpitations. However, everyone may not experience these side effects. If you experience any unusual symptoms, contact your healthcare provider.
Q4.
Can I stop taking Pletoz 50mg Tablet if I feel better?
It is essential not to stop taking Pletoz 50mg Tablet without consulting your healthcare provider, even if you feel better. Abruptly discontinuing the medication can lead to a return of symptoms or other health complications. Always follow your doctor's instructions regarding the duration of treatment.
Q5.
Can Pletoz 50mg Tablet be taken with food?
Pletoz 50mg Tablet is usually taken at least half an hour before or two hours after meals. Consult your healthcare provider or read the medication guide for specific instructions on administering this medication.
Q6.
What should I do if I overdose on Pletoz 50mg Tablet?
If you suspect an overdose of Pletoz 50mg Tablet or experience symptoms such as severe dizziness, fainting, or difficulty breathing, seek immediate medical help. Contact a poison control center or visit the nearest emergency room for assistance.
Fact Box of Pletoz 50mg Tablet
Molecule name: Cilostazol | Therapeutic class: Platelet aggregation inhibitor |
Pharmacological class: PDE3 inhibitor | Indications: 1. Plaque psoriasis 2. Psoriatic arthritis |
References
- Mylan, Electronic medicines compendium (EMC), [Revised on 9th Mar 2020] [Accessed on 19th Oct 2023],https://www.medicines.org.uk/emc/product/2609/smpc#gref
- Otsuka America Pharmaceutical Inc., US Food and Drug Administration, [Revised on July 2017 ] [Accessed on 19th 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/020863s024lbl.pdf
Disclaimer
MrMed’s primary intention is to ensure that its consumers get information that experts, accurate and trustworthy, review. The information and contents of this website are for informational purposes only. They are not intended to substitute for professional medical advice, diagnosis, or treatment. Please seek your doctor's advice and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.
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Author Details
Written By
Dr. Archana Gupta
BDS
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 28 Sep 2026 | 07:16 AM (IST)
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