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Posafung 300mg Injection
Prescription Required
Salt Composition : Posaconazole
Manufacturer : GUFIC BIOSCIENCE LTD
Origin of Medicine : India
1 Vial(s) Of 16.7ml
Introduction to Posafung 300mg Injection
Posafung 300mg Injection belongs to a class of drugs called azole antifungals containing the active ingredient Posaconazole. It is used to treat and prevent certain fungal infections. The medication is commonly prescribed for preventing and treating invasive fungal infections in patients with weak immune systems, such as those undergoing cancer chemotherapy, stem cell transplantation, or those with HIV/AIDS. It also treats certain fungal infections in individuals who cannot tolerate or have not responded to other antifungal treatments.
This drug is contraindicated in individuals with known hypersensitivity or allergy to other antifungal medications like ketoconazole, fluconazole, itraconazole, or voriconazole. Before taking Posafung 300mg Injection, it is necessary to consult with your physician if you have certain heart conditions like abnormal heart rhythm (long QTc interval), weakness of the heart muscle, heart failure, or any heart rhythm disturbances, or if you experience severe kidney problems, diarrhea or vomiting while on treatment with this drug, it's important to inform your physician immediately, as these conditions may affect the medicine's effectiveness.
Posafung 300mg Injection may affect the levels of potassium, magnesium, or calcium in the blood. If you have any problems with these electrolyte levels, your doctor will monitor you closely during treatment. If you are taking medications such as vincristine, vinblastine, or any other vinca alkaloids drugs which are used to treat cancer, you should also inform your physician before initiating the treatment. If you are pregnant, use this drug only if your doctor advises. Taking this drug while breastfeeding may be unsafe because it passes into breast milk and affects the child. Do not breastfeed while taking this medicine.
Uses of Posafung 300mg Injection
- Treatment of fungal infections
Therapeutic Effects of Posafung 300mg Injection
Posafung 300mg Injection works by inhibiting the synthesis of ergosterol, a vital component of the fungal cell membrane. This disruption weakens the membrane, leading to cell death, and effectively treats fungal infections.
Interaction of Posafung 300mg Injection with other drugs
Inform your physician about all your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications such as terfenadine, astemizole, cisapride, pimozide, halofantrine, and quinidine may interact with Posafung 300mg Injection and reduce effectiveness by causing undesirable side effects.
More Information about Posafung 300mg Injection
- Store Posafung 300mg Injection below (30°C).
- Protect from light and moisture.
How to consume Posafung 300mg Injection
Posafung 300mg Injection can be administered only as an intravenous injection into a vein by your physician in a hospital setting. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition.Â
Safety Advices for Posafung 300mg Injection
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Pregnancy
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If you are pregnant, suspecting, or planning for the pregnancy, consult your doctor for more advice before taking Posafung 300mg Injection.
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Breast Feeding
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Taking Posafung 300mg Injection while breastfeeding may be unsafe because it passes into breast milk and affects the child. Do not breastfeed while taking this medicine.
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Lungs
  Inform your doctor if you have liver disease because the Posafung 300mg Injection should be used cautiously with a liver condition.
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Liver
  It is unknown whether Posafung 300mg Injection is safe for patients with lung problems. Inform your physician if you have lung disease before starting the treatment.Â
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Alcohol
 ÂIt is unknown whether consuming alcohol during treatment with Posafung 300mg Injection is safe. Please speak with your physician.
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Driving
  Some side effects of Posafung 300mg Injection may impair your ability to drive or operate machinery safely. It is unsafe to administer this drug.
Side Effects of Posafung 300mg Injection
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious
- Serious allergic reactions
- Skin rash or ulcers in the mouth, bruising, pale skin
- Yellow discoloration of eyes and skin, abdominal pain
Common
- Loss of appetite
- Low white blood cells
- Mild increase in blood pressure
- Diarrhea
- Nausea, vomiting
- Rectal discomfort
Word of Advice
Before taking this drug, your doctor will likely assess your medical history and perform any necessary tests to determine if it suits your specific condition. They will also provide instructions on taking the medication properly and monitoring your progress during treatment. If you have been prescribed Posafung 300mg Injection and have any questions or concerns about the medication or its potential side effects, be sure to discuss them with your physician for better clarification.
FAQs
Q 1. What conditions does Posafung 300mg Injection treat?
Posafung 300mg Injection treats and prevents invasive fungal infections caused by certain fungi, such as Aspergillus and Candida species. It is commonly prescribed for patients undergoing cancer chemotherapy, stem cell transplantation, or those with HIV/AIDS.
Q 2. What formulations are available for Posafung 300mg Injection?
Posafung 300mg Injection is available in different formulations, including oral suspension, syrup, delayed-release tablets, and intravenous (IV) infusion. The specific formulation and dosing will depend on the individual's condition and the physician's recommendation.
Q 3. Are there any precautions or contraindications for using Posafung 300mg Injection?
Individuals who have had an allergic reaction to other azole antifungal medications, those with certain heart conditions, liver problems, or abnormal potassium, magnesium, or calcium levels in the blood should exercise caution or avoid Posafung 300mg Injection. Always inform your physician about your medical history before initiating the treatment.
Q 4. Are there any side effects associated with Posafung 300mg Injection?
Common side effects of Posafung 300mg Injection include nausea, diarrhea, headache, and abdominal pain. Serious side effects are rare but may also include liver problems and allergic reactions. If you experience any concerning side effects, contact your physician immediately.
Q 5. Can pregnant or breastfeeding individuals take Posafung 300mg Injection?
Posafung 300mg Injection may not be safe during pregnancy, and its use during breastfeeding is not recommended. If you are pregnant, planning to become pregnant, or breastfeeding, discuss the risks and benefits of this drug with your doctor.
Fact Box of Posafung 300mg Injection
Molecule name: Posaconazole | Therapeutic class: Antifungal |
Pharmacological class:Â Azole derivative | Indications: Treatment of fungal infections |
References
- Merck Sharp & Dohme (UK) Limited, Electronic medicines compendium (EMC), [Revised on June 2023] [ Accessed on 20th July 2023], https://www.medicines.org.uk/emc/files/pil.5388.pdf
- Merck & Co. Inc, US FDA, [Revised on Dec 2016] [Accessed on 20th July 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/022003s018s020,0205053s002s004,0205596s001s003lbl.pdf
- KD Tripathi, Antifungal drugs, Essentials of Medical Pharmacology, 7th Edition, 2013, 795.
- Goodman & Gilman's, The Pharmacological Basis of Therapeutics, Antifungal agents, 12th edition, 2011, 1581.
Disclaimer
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