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Prepit 125mg/80mg Kit
Prescription Required
Salt Composition : Aprepitant
Manufacturer : KHANDELWAL LABORATORIES PVT LTD
Origin of Medicine : India
3 Capsule(s) In A Strip
Introduction to Prepit 125mg/80mg Kit
Prepit 125mg/80mg capsule contains the active constituent Aprepitant in two different doses. It belongs to a class of medicines called NK1 Receptor antagonists. It is used with a combination of other medicine to prevent nausea and vomiting caused by chemotherapy (cancer treatment) in adults and children of twelve years and older. Do not take this medicine if you are allergic to this medicine or any of the other ingredients of this medicine.Â
Before taking Prepit 125mg/80mg capsule, it is important to inform your physician about all the medications you are taking recently, including supplements and herbal medicines. Notify your doctor if you planning a pregnancy or think you might be pregnant because this medicine is unsafe to use in such conditions. This medication may reduce the efficacy of hormonal contraceptives. Talk with your doctor about alternative birth control options. Before taking this capsule, inform your doctor if you have liver disorders because the liver is crucial in breaking down medicine. Â
The doctor may therefore have to monitor the condition of the liver. Notify your doctor if you have had any allergic conditions or other diseases. Indigestion, tiredness, headache, hiccups, and loss of appetite are the common side effects of Prepit 125mg/80mg medication. Talk to your doctor if you have an intolerance to some sugars as this medication contains sucrose. Do not give this medicine to children under 12 years of age, because the medicines have not been studied in this population.Â
Uses of Prepit 125mg/80mg Kit
- Prevents nausea and vomiting due to chemotherapy
Therapeutic Effects of Prepit 125mg/80mg Kit
Prepit 125mg/80mg capsule blocks the action of a natural substance called neurokinin in the brain that causes nausea and vomiting. This medicine reduces the severity of chemotherapy-induced nausea and vomiting.
Interaction of Prepit 125mg/80mg Kit with other drugs
Inform your healthcare provider about all your medicines, including prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products. Certain medications, such as Pimpzide, Terfenadine, and Cisapride may interact with Prepit 125mg/80mg and reduce effectiveness by causing undesirable side effects.
More Information about Prepit 125mg/80mg Kit
- Store at room temperature 20°C to 25°C.
- Keep out of sight and reach of children.
- Store in the original package in order to protect it from moisture.
How to consume Prepit 125mg/80mg Kit
Swallow the Prepit 125mg/80mg capsule as a whole with water. Do not crush or chew the capsules. These capsules can be taken with or without food. Do not take more than recommended. If this medicine is prescribed, your physician will choose the dosage based on your medical condition because it differs for each person.
Safety Advices for Prepit 125mg/80mg Kit
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Pregnancy
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This medication is unsafe because it may harm your unborn baby. Inform your physician if you are pregnant or planning to get pregnant before taking the Prepit 125mg/80mg capsule. It will be given to you if clearly needed.
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Breast Feeding
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It is unknown whether Prepit 125mg/80mg is excreted in human milk. So, it is not recommended to breastfeed while taking this capsule. Inform your physician before taking this medicine.
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Lungs
  Inform your doctor, if you have or had any lung condition before starting to take Prepit 125mg/80mg. Contact your physician immediately if you experience any lung-related symptoms such as difficulty to breath.Â
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Liver
  Inform your physician if you have any liver disorders before taking the Prepit 125mg/80mg capsule, as this medication should be used with caution in liver disorder patients.Â
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Alcohol
 ÂIt is unknown whether consuming alcohol with Prepit 125mg/80mg. Consult your doctor for more information.Â
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Driving
  The medicine may make you dizzy. Avoid driving or handling heavy machines if you are unwell.
Side Effects of Prepit 125mg/80mg Kit
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.
Serious
- Allergic reactions (rash, itching, difficulty breathing, or swallowing)
Common
- Tiredness
- Increased liver enzyme
- Indigestion
- Constipation
- Loss of appetite
- Hiccups
- Headache
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Word of Advice
Report to your doctor if you are intolerant to any type of sugar because Prepit 125mg/80mg contains sucrose. It is not advised for patients under the age of 12. Notify your doctor if you are pregnant or planning to get pregnant or if you are breastfeeding. It is not recommended to consume this medicine if you have any underlying liver conditions. Your doctor may monitor your liver to understand its functioning level.Â
FAQs
Q 1. Can Prepit 125mg/80mg be taken with other medications?
Prepit 125mg/80mg can be taken with other antiemetic drugs to provide more comprehensive prevention of chemotherapy-induced nausea and vomiting.
Q 2. Can Prepit 125mg/80mg be used to treat other conditions?
Prepit 125mg/80mg is primarily used to prevent nausea and vomiting caused by chemotherapy or surgery, but it may also be used to treat other conditions, such as migraine headaches.
Q 3. Why patients with liver conditions should not consume Prepit 125mg/80mg?
Because the Prepit 125mg/80mg initially gets metabolized in the liver. Hence patients with liver disorders will feel difficult to metabolize this medicine which may lead to an increased risk of side effects.
Q 4. What should I inform my doctor about before starting with Prepit 125mg/80mg?
You need to inform if you have any underlying liver conditions if you are allergic to Prepit 125mg/80mg, and if you are intolerant to sucrose or any other sugar.
Q 5. Is Prepit 125mg/80mg safe for use during pregnancy?
Prepit 125mg/80mg should only be used during pregnancy if the potential benefits outweigh the potential risks to the fetus.
Fact Box of Prepit 125mg/80mg Kit
Molecule name: Aprepitant | Therapeutic class: Antiemetic |
Pharmacological class: NK1 Receptor antagonists | Indication: Prevents nausea and vomiting due to chemotherapy |
References
- KD Tripathi, Essentials of Medical Pharmacology, Antiemetic, Prokinetic and Digestant Drugs, 7th edition, 2013, 669-670.
- Goodman & Gilman’s, The Pharmacological Basics of Therapeutics, Treatment of disorders of bowel motility and water flux, 12th edition, 2011, 1345.
- Ethypharm, Electronic Medicines Compendium (EMC), [Revised on Oct 2022]; [Accessed on 19th April 2023], https://www.medicines.org.uk/emc/files/pil.14650.pdf
- Merck Sharp & Dohme Corp, US Food and Drug Administration, [Revised date April 2015], [Accessed on 19th April 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/021549s025lbl.pdf
Disclaimer
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