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Primigyn Gel
Prescription Required
Salt Composition : Dinoprostone
Manufacturer : BHARAT SERUMS & VACCINES LTD
Origin of Medicine : India
1 Tube Of 3gm
Introduction to Primigyn Gel
Primigyn Gel is a uterotonic medication containing the active ingredient Dinoprostone. This medication is used to induce labour in pregnant women. It facilitates cervical ripening and manages certain pregnancy-related complications. It is a synthetic form of prostaglandin E2, a hormone that influences uterine contractions and cervical changes.
Before receiving Primigyn Gel, it's important to inform your physician about any allergies, sensitivities, existing heart, lung, kidney, or liver disease, previous uterine surgeries, or cesarean sections in your medical history, as well as any ongoing use of medications, supplements, or herbal products. This information will help ensure the safe and effective use of the medication for your specific situation.Â
This medicine can only be given in the later stages of pregnancy to induce labour. Consult your doctor for more advice. While this drug is found in breast milk, it poses no harm to your baby. Therefore, you can continue breastfeeding without concern after childbirth.
Uses of Primigyn Gel
- Induce labor in pregnant women.
Therapeutic Effects of Primigyn Gel
Primigyn Gel works by binding to specific receptors on the uterine muscle cells, leading to an increase in contractions and softening of the cervix. This helps to initiate labor or prepare the cervix for childbirth.
Interaction of Primigyn Gel with other drugs
Inform your physician about all your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Primigyn Gel and reduce effectiveness by causing undesirable side effects.
More Information about Primigyn Gel
- Store Primigyn Gel in a refrigerator between 2°C to 8°C.
- Do not freeze.
How to consume Primigyn Gel
Primigyn Gel is administered intravaginally for the purpose of cervical ripening or labor induction. Using a sterile applicator, the physician gently inserts the gel into the patient's vagina and places it close to the cervix. After application, the patient is monitored for some time.
Safety Advices for Primigyn Gel
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Pregnancy
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Primigyn Gel will only be given in the later stages of pregnancy to induce labour. Consult your doctor for more advice.
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Breast Feeding
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While Primigyn Gel are found in breast milk, they pose no harm to your baby. Therefore, you can continue breastfeeding without concern after childbirth.
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Lungs
  Primigyn Gel should be cautiously used in patients with lung diseases. Inform your doctor if you have lung issues before initiating the therapy.
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Liver
  Primigyn Gel should be cautiously used in patients with severe liver diseases. Dose adjustments are necessary. Inform your doctor if you have liver issues before initiating the therapy.
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Alcohol
 ÂIt is unknown whether consuming alcohol interacts with the Primigyn Gel. Please consult your doctor for more advice.
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Driving
  It is unknown whether Primigyn Gel alters driving ability. However, if you experience side effects like tiredness or drowsiness, avoid driving and using machines.
Side Effects of Primigyn Gel
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious side effects of Primigyn Gel are:
- Severe abdominal pain.
- Heavy vaginal bleeding.
- Signs of an allergic reaction (swelling, rash, itching, difficulty breathing).
Common side effects of Primigyn Gel are:
- Uterine contractions.
- Abdominal pain.
- Nausea and vomiting.
- Diarrhea.
- Headache.
- Changes in blood pressure.
Word of Advice
Primigyn Gel can cause uterine contractions, which are necessary for labor but could potentially be harmful if used inappropriately. It's necessary to ensure that the medication is administered correctly to avoid excessive contractions or complications.
FAQs
Q 1. How is Primigyn Gel administered?
Primigyn Gel can be administered in various forms, including vaginal suppositories, gels, and inserts. The specific form and dosage will depend on the medical condition being treated and the physician's recommendation.
Q 2. Who should not use Primigyn Gel?
Primigyn Gel should be used with caution or avoided in individuals with a history of certain medical conditions, such as hypersensitivity to prostaglandins, a history of uterine surgery, previous cesarean section, or abnormal fetal heart rate. Pregnant individuals with certain medical complications may also not be suitable candidates for this drug.
Q 3. Can Primigyn Gel be used at home?
No, Primigyn Gel is usually administered in a healthcare setting, such as a hospital, under the supervision of medical professionals due to its potential for causing strong uterine contractions and the need for monitoring.
Q 4. How does Primigyn Gel work?
Primigyn Gel works by increasing uterine contractions and softening the cervix. It helps to prepare the cervix for labor and delivery.
Q 5. Are there any side effects of Primigyn Gel?
Some common side effects of Primigyn Gel include uterine contractions, abdominal pain, nausea, vomiting, diarrhea, headache, and changes in blood pressure. Serious side effects are rare but can include allergic reactions and uterine rupture.
Fact Box of Primigyn Gel
Molecule name: Dinoprostone | Therapeutic class: Uterotonic agents |
Pharmacological class:Â Prostaglandin E2 (PGE2) | Indications: Induce labor in pregnant women |
References
- Pfizer, Electronic medicines compendium (EMC), [ Revised on June 2021] [ Accessed on 26th August 2023], https://www.medicines.org.uk/emc/files/pil.1090.pdf
- Pfizer, US Food and Drug Administration, [ Revised on Feb 2010] [ Accessed on 26th August 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/019617s010lbl.pdf
- KD Tripathi, Essentials of Medical Pharmacology, Prostaglandins, Leukotrienes and Platelet-activating factor, 7th edition, 2013, 189.
- Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Contraception and Pharmacotherapy of Obstetrical, 12th edition, 2011, 1850.
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