All Substitutes



Want to know more?
Read Our Editorial Policy

Did you find this information helpful?

25% Off

Prolavir LR Tablet

Prescription Required

Salt Composition : Lopinavir,ritonavir

Manufacturer : LAURUS LABS LTD

Origin of Medicine : India

MRP: 6099
Price :4575
You Save :1524 (25%)

30 Tablet(s) In A Bottle

Delivery By -

Introduction to Prolavir Lr Tablet

Prolavir LR Tablet is an antiretroviral drug belonging to the protease inhibitors category, containing the active ingredient Lopinavir, Ritonavir. It is used in the treatment of HIV-1 infection. It is a Human immunodeficiency virus that mainly occurs when a person's immune system is attacked and weakened by the human immunodeficiency virus (HIV). This infection progressively weakens the immune system, making individuals more susceptible to opportunistic infections.

Suppose you have Hepatitis B, Hepatitis C, or other liver problems. In that case, you may have a greater risk of developing new or worsening liver illness during treatment with Prolavir LR Tablet. Tell your healthcare provider immediately if you have any signs and symptoms of liver problems, such as loss of appetite, dark-colored urine, yellow skin and whites of eyes(jaundice), and pale-colored stools. People with high levels of certain fat (triglycerides) have a greater chance of developing pancreatitis(a condition caused by inflammation of the pancreas, a gland behind the stomach). If you have a history of pancreatitis, you may have a greater chance of it returning during treatment with this drug.

During the early stages of HIV-1 treatment, some patients may experience an inflammatory response to opportunistic infections. This condition is called immune reconstitution syndrome. It can occur after starting the drug or other antiretroviral therapies. Knowing this possibility and monitoring for any signs of worsening infections or inflammatory symptoms is necessary. Inform your healthcare provider if the symptoms concern you or persist longer than usual. It is advised to avoid using Prolavir LR Tablet if you are mainly allergic to it or its ingredients. Tell your doctor about all the medications you have been taking recently, including herbal and supplements, before taking this drug.

Uses of Prolavir Lr Tablet

  • Treatment of HIV-1 infection

Therapeutic Effects of Prolavir Lr Tablet

Prolavir LR Tablet work together to inhibit the protease enzyme, which is necessary for the replication of HIV. By blocking this enzyme, this drug prevents the virus from multiplying and spreading in the body. It mainly helps reduce the viral load and slow the progression of HIV infection.

Interaction of Prolavir Lr Tablet with other drugs

Inform your healthcare provider about all your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications such as carbamazepine, phenobarbital, phenytoin, efavirenz, nevirapine, and nelfinavir may interact with Prolavir LR Tablet and reduce effectiveness by causing undesirable side effects.

More Information about Prolavir Lr Tablet

  • Store Prolavir LR Tablet at room temperature below ( 30°C).
  • Keep the tablet out of reach of children and pets.

How to consume Prolavir Lr Tablet

It is an orally available prescription drug. Your doctor will decide the dose and duration of the drug based on the disease condition and other factors. Always take Prolavir LR Tablet as prescribed by your doctor. Take the tablet with or without food. Do not break, chew, crush, or break the tablet. Swallow the whole tablet with water.

Safety Advices for Prolavir Lr Tablet

Image Not Available  



Your doctor shall prescribe Prolavir LR Tablet only if it is essential and the benefits outweigh the risks.

Image Not Available  

Breast Feeding


Taking Prolavir LR Tablet during breastfeeding is unsafe because it tends to get excreted in human milk

Image Not Available  



It is unknown whether Prolavir LR Tablet can be prescribed for patients with lung problems. Consult your doctor if you have any lung diseases before starting the treatment.

Image Not Available  



Prolavir LR Tablet should be cautiously administered in patients with severe liver diseases. Dose adjustments are necessary for severe liver failure. Inform your physician if you have liver problems before initiating the therapy.

Image Not Available  



Consuming alcohol may affect the effectiveness of Prolavir LR Tablet. It is highly advised to stop consuming alcohol if you take this medicine. 

Image Not Available  



Driving vehicles or operating heavy machinery is unsafe after taking Prolavir LR Tablet it may cause dizziness and impair concentration.

Side Effects of Prolavir Lr Tablet

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.


  • Osteonecrosis (stiffness and pain in joints, difficulty moving)
  • Lactic acidosis (breathing difficulties along with weakness in limbs, stomach pain, and drowsiness)
  • Symptoms of muscle weakness or infection
  • Changes in body fat
  • Inflammation of the pancreas (nausea, vomiting, along with abdominal pain)
  • Liver problems (yellow skin and whites of eyes, dark-colored urine, pale-colored stools, loss of appetite)
  • High blood sugar (Increased thirst or urination)
  • Severe allergic reactions


  • Diarrhea
  • Increased lipid levels in the blood

Word of Advice

To prevent the spread of HIV infection, avoid sharing needles or syringes, which can transmit HIV-1 infections easily. It's necessary for individuals who use injectable drugs to use sterile needles and syringes and never share them with others. Personal items like toothbrushes, razor blades, or anything with body fluids or blood on them should also be avoided. They should not be shared because HIV-1 can be present in blood and certain body fluids, and sharing these items could mainly transmit the virus. 

Since this drug is unsafe for breastfeeding because HIV infection can be passed to the baby in the breast milk, alternative feeding methods can be followed to nourish the infant's growth. If you forget to take Prolavir LR Tablet for the entire day, take your usual dose the next day. However, do not double-dose yourself.


Q 1. What is the actual mechanism of Prolavir LR Tablet?

Prolavir LR Tablet interfere with the protease enzyme necessary to produce new viruses in HIV-infected cells. By inhibiting this enzyme, they prevent the virus from multiplying and spreading in the body.

Q 2. Are there any special precautions or warnings associated with Prolavir LR Tablet?

Yes, there are certain precautions and warnings to consider Prolavir LR Tablet may have potential interactions with other medications, can affect liver function, and may cause changes in heart rhythm. It's important to discuss any pre-existing medical illness or concern with your doctor before starting this medication.

Q 3. What should I say to the physician before taking Prolavir LR Tablet?

Before taking Prolavir LR Tablet, you should inform your physician about any medical illness, including liver or kidney problems, diabetes, heart disease, pancreatitis, or any history of drug allergies. Also, inform about all the medications, supplements, or herbal products you are currently taking, as this tablet can interact with other drugs and cause adverse effects.

Q 4. What is the most necessary information I should know about Prolavir LR Tablet?

Suppose you have Hepatitis B, Hepatitis C, or other liver problems. In that case, you may have a greater risk of developing new or worsening liver illness during treatment with Prolavir LR Tablet. Tell your healthcare provider immediately if you have any signs and symptoms of liver problems.

Q 5. How should I store Prolavir LR Tablet?

Store Prolavir LR Tablet at room temperature, between (20°C to 25°C). Please do not keep the tablets out of the container for longer than two weeks, especially in areas with a lot of humidity. Keep the container closed tightly.

Q 6. What strength is Prolavir LR Tablet?

It is available in tablet form, and each tablet contains 200 milligrams of lopinavir and 50 milligrams of Ritonavir. The combination of Prolavir LR Tablet in Lopimune is formulated to provide an effective antiviral treatment for certain conditions, including HIV.

Fact Box of Prolavir Lr Tablet

Molecule name: Lopinavir, Ritonavir

Therapeutic class: Antiretroviral

Pharmacological class:  Protease inhibitors

Indications:  Treatment of HIV-1 infection


  1. AbbVie Deutschland GmbH & Co. KG, Electronic medicines compendium (EMC), [ Revised on March 2021] [ Accessed on 17th May 2023],
  2. AbbVie Inc, US Food and Drug Administration, [ Revised on December 2018] [ Accessed on 17th May 2023],
  3. KD Tripathi, Essentials of Medical Pharmacology, Antiviral drugs, 7th edition, 2013, 809 - 811.
  4. Goodman & Gilman's, The Pharmacological Basis of Therapeutics, Antiretroviral agents and treatment of HIV infection, 12th edition, 2011, 1645-1654.


MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.

4000+ products

We maintain strict quality controls on all our partner retailers, so that you always get standard quality products.

Secure Payment

100% secure and trusted payment protection

Easy Return

We have a new and dynamic return window policy for medicines and healthcare items. Refer FAQs section for more details.