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Rojuzda 75mg Injection

Prescription Required

cold-chain

Salt Composition : Luspatercept

Manufacturer : BRISTOL MYERS SQUIBB

Origin of Medicine : United States of America

MRP: 101000
Price :90900
You Save :10100 (10%)

1 Vial(s)

Prepaid Only. Non-Returnable

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Introduction to Rojuzda 75mg Injection

Rojuzda 75mg injection contains an active component as luspatercept. It is a medication that has been developed for the treatment of certain types of anemia. Specifically, it treats anemia associated with two rare blood disorders: beta-thalassemia and myelodysplastic syndromes (MDS). Beta-thalassemia is an inherited blood disorder that affects the production of hemoglobin, the protein responsible for carrying oxygen in red blood cells. Myelodysplastic syndromes (MDS) are a group of bone marrow disorders characterized by ineffective blood cell production. One of the primary benefits of this medication is its ability to reduce the frequency of blood transfusions in patients with anemia associated with beta-thalassemia and MDS.

Rojuzda 75mg injection should not be used in individuals who have a known hypersensitivity or allergic reaction to the medication or any of its components. It may increase the risk of blood clot formation. Suppose you have a history of blood clots or are at an increased risk for clotting disorders. In that case, your healthcare provider should carefully evaluate the potential risks and benefits of Rojuzda 75mg injection treatment. Tell your healthcare provider if you have any other medical conditions or are undergoing treatments before taking it.


Uses of Rojuzda 75mg Injection

Rojuzda 75mg injection is used in treating the following:

  • Beta-thalassemia
  • Myelodysplastic syndromes

Therapeutic Effects of Rojuzda 75mg Injection

Rojuzda 75mg injection is a medication with a therapeutic effect that promotes red blood cell production and reduces the need for blood transfusions in individuals with beta-thalassemia and myelodysplastic syndromes (MDS). By targeting proteins involved in regulating red blood cell formation, this medication stimulates the production of mature red blood cells, leading to increased hemoglobin levels and improved oxygen-carrying capacity. This not only reduces the frequency of blood transfusions but also enhances the quality of life by alleviating fatigue and improving overall well-being. Additionally, it may have disease-modifying effects, potentially mitigating organ complications associated with chronic anemia.


Interaction of Rojuzda 75mg Injection with other drugs

Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Rojuzda 75mg injection, reducing effectiveness by causing undesirable side effects.


More Information about Rojuzda 75mg Injection

  • Stored in the refrigerator at a temperature between 2°C to 8°C (36°F to 46°F).
  • Keep away from moisture, heat, and light.
  • It should not be frozen.
  • Keep away from children and pets.

How to consume Rojuzda 75mg Injection

To use Rojuzda 75mg injection, follow the instructions provided by your healthcare provider or as indicated on the medication label. It is typically administered as an injection. The exact dosing and administration instructions may vary based on the specific condition being treated.


Safety Advices for Rojuzda 75mg Injection

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Pregnancy

  

Rojuzda 75mg injection poses risks to a developing fetus and may cause harm during pregnancy. 

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Breast Feeding

  

The safety of Rojuzda 75mg injection during breastfeeding is not well established, and it is recommended to exercise caution and consult a healthcare professional before using this medication while breastfeeding.

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Lungs

  

If you have a pre-existing lung condition or any concerns about the impact of Rojuzda 75mg injection on your respiratory health, it is crucial to discuss these concerns with your healthcare provider.

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Liver

  

Individuals with pre-existing liver conditions or underlying liver diseases need to consult a healthcare provider before starting treatment.

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Alcohol

  

It is generally recommended to avoid consuming alcohol while taking Rojuzda 75mg injection. Alcohol can interact with theophylline, one of the components of this medication, and potentially increase the risk of side effects.

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Driving

  

Rojuzda 75mg injection may cause side effects that can impair driving ability and overall alertness. Common side effects include dizziness, headache, and tremors, affecting coordination and reaction time.


Side Effects of Rojuzda 75mg Injection

Rojuzda 75mg injection causes some side effects like all medications, although not everyone will experience them. 

Serious:

  • Blood clots
  • Hypertension (high blood pressure)
  • Stroke
  • Heart attack
  • Venous thromboembolism (blood clot in a vein)
  • Thrombosis (blood clotting disorder)
  • Embolism (blockage of blood vessels by a clot or other substance)
  • Hemorrhage (excessive bleeding)
  • Allergic reactions (rare, but may include rash, itching, swelling, severe dizziness, or difficulty breathing)

Common:

  • Headache
  • Fatigue
  • Dizziness
  • Nausea
  • Joint pain
  • Bone pain
  • Muscle pain
  • Injection site reactions (e.g., pain, redness, swelling)

Word of Advice

To ensure the safe and effective use of Rojuzda 75mg injection, it is important to approach its use with caution and adhere to the advice given by healthcare provider. Regular monitoring of blood pressure, liver function, kidney function, and iron levels are typically recommended during treatment. Any abnormalities or changes in these parameters should be promptly addressed and managed accordingly. Individuals with a history of blood clots, clotting disorders, or significant bleeding episodes should be closely monitored during treatment due to the increased risk of thrombotic events and hemorrhage. It is important to promptly report any signs of bleeding, such as unusual bruising, nosebleeds, or blood in the urine or stool, to your healthcare provider. You should discuss the potential risks of this medication during pregnancy or breastfeeding with your healthcare provider and communicate openly with your healthcare provider about your medical history, ongoing treatments, and any concerns you may have. By being proactive and informed and maintaining regular communication with your healthcare provider, you can maximize the benefits of this medicine while minimizing potential risks.


FAQs

Q 1. Can Rojuzda 75mg injection be used in children?

Rojuzda 75mg injection is not approved for children, as its safety and efficacy have not been established in pediatric populations. It is primarily indicated for adult patients with specific medical conditions.

Q 2. Can Rojuzda 75mg injection be used in patients with kidney disease?

Rojuzda 75mg injection may require dose adjustment or close monitoring in patients with kidney disease. Your healthcare provider will assess your kidney function and determine the appropriate dose or any necessary precautions based on your circumstances.

Q 3. Can Rojuzda 75mg injection be used during chemotherapy or radiation therapy?

The use of Rojuzda 75mg injection in conjunction with chemotherapy or radiation therapy has yet to be extensively studied. It is important to discuss your treatment plan with your healthcare provider to determine the most appropriate approach and any potential interactions or effects.

Q 4. Can Rojuzda 75mg injection be used in patients with a history of cardiovascular disease?

Rojuzda 75mg injection should be used cautiously in patients with a history of cardiovascular disease, as it may increase the risk of cardiovascular events such as heart attack or stroke. Your healthcare provider will assess your cardiovascular health and determine the suitability of this medication treatment.

Q 5. Can Rojuzda 75mg injection cause any side effects in patients with a history of bleeding disorders?

Patients with a history of bleeding disorders should be closely monitored during Rojuzda 75mg injection treatment due to the increased risk of hemorrhage. It is important to discuss your medical history with your healthcare provider to determine the appropriate precautions and monitoring plan.

Q 6. Can Rojuzda 75mg injection cause fertility problems?

Rojuzda 75mg injection may affect fertility in both males and females. If you have concerns about fertility or family planning, discussing this with your healthcare provider before starting treatment with Rojuzda 75mg injection is important. They can provide guidance and recommendations based on your circumstances.


Fact Box of Rojuzda 75mg Injection

Molecule name: Luspatercept

Therapeutic class: Hematopoietic agent

Pharmacological class: Erythroid maturation agent



 

Indications: 

1. Beta-thalassemia

2. Myelodysplastic syndromes


References

  1. Lonza Biologics Tuas Pte Ltd, European Medicines Agency, [Revised on 25 June 2020] [Accessed on 17th June 2023], https://www.ema.europa.eu/en/documents/product-information/reblozyl-epar-product-information_en.pdf
  2. Acceleron Pharma, Inc, US Food and Drug Administration, [Revised on April 2020] [Accessed on 17th June 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/761136orig2lbl.pdf

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