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Rosuvas EZ 10mg Tablet

Prescription Required

Salt Composition : Rosuvastatin,ezetimibe

Manufacturer : EMCURE PHARMACEUTICALS LTD

Origin of Medicine : India

MRP: 358.35
Price :305
You Save :53 (15%)

10 Tablet(s) In A Strip


Introduction to Rosuvas Ez 10mg Tablet

Rosuvas EZ 10mg tablet contains two active ingredients in one tablet. One of the active substances is rosuvastatin, which belongs to the group of medications called HMG-CoA reductase inhibitors (statins); the other active substance is ezetimibe belonging to the group of medications called 2-Azetidinones. This combination is used to reduce total cholesterol levels, LDL (bad cholesterol), and fatty substances called triglycerides in your blood. It also helps to raise levels of HDL (good cholesterol).   

Rosuvas EZ 10mg tablet is used in patients whose cholesterol levels cannot be controlled by a cholesterol-lowering diet alone. It is used in patients with heart disease. This medicine reduces the risk of heart attack, stroke, surgery to increase heart blood flow, or hospitalization for chest pain. This tablet does not help you lose weight. Do not take this medicine if you are allergic to rosuvastatin, ezetimibe, or any of the other ingredients of this medicine. The use of this medicine is not recommended in children and adolescents under the age of 18 years. 

Do not take Rosuvas EZ 10mg tablet if you have liver disease, severe kidney impairment, and if you are pregnant or breastfeeding. Stop taking this medicine and inform your doctor immediately if you develop a severe skin rash or skin peeling, blistering, or mouth sores after taking this tablet. Inform your physician if you have kidney or liver diseases, muscle pain, respiratory failure, and are over 70 years old. Notify your physician if you regularly drink alcohol. This medicine may increase your chances of developing diabetes. 


Uses of Rosuvas Ez 10mg Tablet

  • Reduces total cholesterol, LDL cholesterol, and triglyceride levels in the blood.

Therapeutic Effects of Rosuvas Ez 10mg Tablet

This medicine reduces your cholesterol in two ways: it reduces the cholesterol absorbed in your digestive tract and the cholesterol your body makes by itself. Rosuvastatin is an HMG CoA-reductase inhibitor; it increases the number of hepatic LDL receptors on the cell surface to enhance the uptake and breakdown of LDL and inhibits hepatic synthesis of VLDL (very low-density lipoprotein), thereby reducing the total number of cholesterol levels. 

Ezetimibe inhibits cholesterol absorption in the small intestine; it localizes at the brush border of the small intestine and decreases the delivery of intestinal cholesterol to the liver; this reduces hepatic cholesterol stores and increases cholesterol clearance from the blood.


Interaction of Rosuvas Ez 10mg Tablet with other drugs

Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products. Certain medications interact with Rosuvas EZ 10mg tablet and reduce their effectiveness by causing undesirable side effects. Do not take cyclosporin while taking this medicine.  


More Information about Rosuvas Ez 10mg Tablet

  • Store the Rosuvas EZ 10mg tablet at 20°C to 25°C
  • Protect the medicine from light and excessive moisture.
  • Keep the medicine out of reach of children and pets
  • If you forgot to take the tablet, simply take your next dose at the scheduled time. Do not take a double dose to make up for a forgotten dose.

How to consume Rosuvas Ez 10mg Tablet

Your doctor will decide the dose and duration of Rosuvas EZ 10mg tablet based on the disease condition and other factors. Always take this medicine as prescribed by your doctor. Take the tablet at the same time every day, with or without food. Do not break, chew, crush, or break the tablet. Swallow the whole tablet with water. 


Safety Advices for Rosuvas Ez 10mg Tablet

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Pregnancy

  

Do not take Rosuvas EZ 10mg tablet if you are pregnant because this may harm the unborn baby. Inform your physician if you are pregnant, suspecting pregnancy, or planning to get pregnant during the treatment. Use effective contraception during the treatment. 

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Breast Feeding

  

Breastfeeding is not recommended in patients taking Rosuvas EZ 10mg tablet because the medicine passes into the breast milk in small amounts and may harm your baby. Do not breastfeed during the treatment. 

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Lungs

  

It is unknown whether Rosuvas EZ 10mg tablet can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.

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Liver

  

Rosuvas EZ 10mg tablet is contraindicated in patients with acute liver failure.  Inform your physician if you have any liver disease before initiating the therapy.

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Alcohol

  

It is unsafe to drink alcohol while you take Rosuvas EZ 10mg tablet. 

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Driving

  

Rosuvas EZ 10mg tablet does not alter your ability to drive and operate heavy machinery. If you feel dizzy, consult the doctor before driving or using machines. 


Side Effects of Rosuvas Ez 10mg Tablet

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. 

 Common 

  • Abdominal pain
  • Constipation, diarrhea
  • Nausea
  • Increased liver enzymes
  • Muscle, bone, and joint pain
  • Headache
  • Fatigue
  • Cold and fever 

Serious  

  • Increased blood sugar levels
  • Increased liver enzymes and liver injury
  • Muscle problems
  • Kidney problems
  • Sleep disturbances

Word of Advice

You should follow a low-cholesterol diet and exercise while taking this medicine. If you need to take an antacid, take it at least 2 hours after using this medicine. Inform your doctor if you have thyroid problems before initiating the treatment. This medicine may affect the liver; for this reason,  your doctor will regularly carry out liver function test during the treatment. You are likely to be at risk of developing diabetes if you have high levels of sugars and fats in your blood, are overweight, and have high blood pressure.


FAQs

Q 1. Can Rosuvas EZ 10mg tablet be taken at any time of the day?

Yes, Rosuvas EZ 10mg tablet can be taken at any time of the day. However, taking it at the same time each day is generally recommended for better medication adherence. It can be taken with or without food, as directed by your healthcare provider.

Q 2. Can I stop taking my other cholesterol-lowering medications if I start taking Rosuvas EZ 10mg tablet?

Depending on your specific condition, your doctor may sometimes recommend stopping, decreasing the dose, or taking other cholesterol-lowering medications. It is important to follow the guidance of your healthcare professional completely while taking this medicine.

Q 3. Can Rosuvas EZ 10mg tablet cause muscle pain or weakness?

Muscle pain or weakness is a potential side effect of Rosuvas EZ 10mg tablet, although it is relatively rare. If you experience unexplained muscle pain, tenderness, or weakness, especially if accompanied by fever or malaise, it is important to contact your healthcare provider promptly. They can evaluate your symptoms and make any necessary adjustments to your medication regimen.

Q 4. Following a special diet while taking Rosuvas EZ 10mg tablet is necessary?

While taking Rosuvas EZ 10mg tablet, following your cholesterol-lowering diet with exercises is generally recommended. A diet low in saturated fats and cholesterol can support the effectiveness of the medication in managing cholesterol levels. Your healthcare provider or a registered dietitian can provide specific dietary recommendations tailored to your needs.

Q 5. Can Rosuvas EZ 10mg tablet be taken with certain supplements or herbal products?

Certain supplements or herbal products may interact with Rosuvas EZ 10mg tablet, affecting its effectiveness or increasing the risk of side effects. It is important to inform your healthcare provider about all the supplements or herbal products you are taking before starting or modifying your medication regimen.


Fact Box of Rosuvas Ez 10mg Tablet

Molecule name: Rosuvastatin + Ezetimibe

Therapeutic class:  Lipid-Lowering Agents

Pharmacological class: 

1. Rosuvastatin - HMG-CoA reductase inhibitor (Statins) 

2. Ezetimibe - 2-Azetidinones

Indications: Reduce total cholesterol, LDL and triglycerides in the blood.


References

  1. Package leaflet: Information for the user rosuvastatin/Ezetimibe Abbott. Available at: https://file.wuxuwang.com/hma/NL_H_4917_001_FinalPL.pdf  (Revised: March 2023) (Accessed: 29 May 2023).
  2. “Highlights Of Prescribing Information - Rosuvastatin + Ezetimibe.” (Revised March 2021) https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/213072s000lbl.pdf
  3. Barrios, Vivencio, and Carlos Escobar. “Fixed-Dose Combination of Rosuvastatin and Ezetimibe: Treating Hypercholesteremia according to Cardiovascular Risk.” Expert Review of Clinical Pharmacology, vol. 14, no. 7, 24 May 2021, pp. 793–806, pubmed.ncbi.nlm.nih.gov/33970743/#:~:text=Rosuvastatin%20is%20a%20high%2Dintensity,to%20reduce%20LDL%2DC%20levels., https://doi.org/10.1080/17512433.2021.1925539 . (Accessed 2 Dec. 2021.) 

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