SANDIMMUN 50MG INJECTION

Introduction:

Sandimmun 50mg Injection is an immunosuppressant medication containing the active constituent called cyclosporine. It helps prevent the rejection of transplanted organs, including stem cell and bone marrow transplantation. Following an organ transplant, our body’s immune system will try to reject the new organ. This medication controls the body’s immune response to accept the transplanted organ. 

Before receiving Sandimmun 50mg Injection, talk to the physician if you have liver problems, kidney problems, gout, high blood potassium levels, infection, low magnesium levels, or if you need to have a vaccination. Limit exposure to the sun while taking this medication. Use sunscreen with high SPF (sun protection factor) and wear protective clothing when you go outside. Avoid drinking grapefruit juice and eating grapefruits while taking this medication.

Make sure you inform your physician of all the medicines, including supplements and herbal medicines, you are taking before you start treatment with this medication.

Uses of Sandimmun 50mg Injection:

• Prevents transplant rejection 

How Sandimmun 50mg Injection works:

Sandimmun 50mg Injection blocks the development of certain cells that usually attack the transplanted part and prevents rejection.

Interactions with other drugs:

Inform your doctor about any medications you are taking or have taken before the treatment.

More information:

• Keep Sandimmun 50mg Injection out of sight and reach of children. 
• Store below 30°C.

References:

1. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Immunosuppressants, tolerogens, and immuno stimulants, 12th edition, 2011, 1011.
2. KD Tripathi, Essentials of Medical Pharmacology, Immunosuppressant drugs, 7th edition, 2013, 878.
3. Novartis Pharmaceuticals UK Limited, Electronic medicines compendium (emc), [ Revised on Sept 2021] [ Accessed on 16th May 2022], https://www.medicines.org.uk/emc/files/pil.1036.pdf   

How to use Sandimmun 50mg Injection:

It will be given to you by your health care professional. Avoid drinking grapefruit juice and eating grapefruits while taking this medication.

Safety advice:

Pregnancy:

Generally, Sandimmun 50mg Injection is not recommended for pregnant women unless the physician thinks it is necessary. You need to inform your doctor if you are pregnant or planning to get pregnant before taking this medicine.

Breastfeeding:

Do not breastfeed during treatment with Sandimmun 50mg Injection. You need to tell your doctor if you are breastfeeding before taking this medicine.

Liver:

It is essential to inform the health care provider if you have any liver disorders, as this medicine needs to be used with caution in liver disorder patients.

Kidney:

It is essential to inform the health care provider if you have any kidney disorders as this medicine needs to be used with caution in liver disorder patients.

Others:

• Inform your physician if you develop high blood pressure, infection, gout, high potassium blood levels, low magnesium levels, or if you need to get a vaccination. 

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.

Serious:

• Shortness of breath, flushing, changes in blood pressure and heartbeat, fluid in the lungs
• Brain problems
• Swelling at the back of the eye
• Low blood cell count

Common:

• High blood pressure
• Headache
• Excessive growth of facial and body hair
• High lipid levels in the blood
• Uncontrollable shaking
• Seizures
• High blood sugar levels
• Tiredness
• Loss of appetite
• Vomiting, nausea
• Diarrhea, abdominal pain
• Numbness or tingling
• Pain in the muscles
• Stomach ulcer
• Acne, hot flushes