a:["$","main",null,{"className":"py-10 max-md:overflow-x-hidden","children":[["$","script",null,{"type":"application/ld+json","dangerouslySetInnerHTML":{"__html":"$1b"}}],["$","$L1c",null,{}],["$","section",null,{"className":"mx-auto max-w-7xl px-4 sm:px-6 lg:px-8","id":"","children":[[["$","$L1d",null,{"hasCustomEntry":true,"customBreadcrumbEntry":[{"name":"Medicine","url":"/products"},{"name":"Spexib 150mg Capsule","url":"#"}]}],["$","span",null,{"aria-hidden":"true","className":"w-px h-px block","style":{"marginLeft":"0.25rem","marginTop":"1rem"}}],[["$","$L1e",null,{"gutter":[48,24],"justify":"space-between","children":[["$","$L1f",null,{"lg":{"order":0,"span":7},"xs":{"order":1,"span":24},"children":[null,false,["$","div",null,{"className":"!sticky top-[140px] hidden md:block","children":["$","$L20",null,{"content":[{"id":"5c27b651-32bc-4581-baf8-35141fcde419","type":"PARA","position":1,"content_placement":1,"data":{"heading":"Introduction to Spexib 150mg Capsule","text":"$21"}},{"id":"bbd652f7-053f-45c3-8c15-d2459e090d14","type":"PARA","position":2,"content_placement":1,"data":{"heading":"Uses of Spexib 150mg Capsule","text":"

Anaplastic lymphoma kinase (ALK) positive non-small cell lung cancer (NSCLC)

"}},{"id":"f27c102d-a12f-4ef2-88f9-6cbe988017fa","type":"PARA","position":3,"content_placement":1,"data":{"heading":"Therapeutic Effects of Spexib 150mg Capsule","text":"

ALK gene is a fusion protein that signals the cells to grow and divide uncontrollably, leading to the development of cancer. Spexib 150mg works by binding to the ALK protein, preventing its activity and stopping the growth and spread of cancer cells.

"}},{"id":"1e406a60-96df-4dc6-abea-36b319cc6a7a","type":"PARA","position":4,"content_placement":1,"data":{"heading":"Interaction of Spexib 150mg Capsule with other drugs","text":"

Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, recent vaccinations, nutritional and vitamin supplements, and herbal products. Certain medications such as ritonavir, Antifungal, antibiotics, anti-epileptics, and other medications may interact with Spexib 150mg and reduce its effectiveness by causing undesirable side effects.

"}},{"id":"44bd7e23-d5da-4373-aa1b-b5a3e8708c59","type":"PARA","position":5,"content_placement":1,"data":{"heading":"More Information about Spexib 150mg Capsule","text":"

Do not store above 30˚C
Keep it in the original container
Keep this medicine out of the sight and reach of children.

"}},{"id":"7be3d30a-ccbb-4b95-a746-cda2507b3f1f","type":"PARA","position":6,"content_placement":1,"data":{"heading":"How to consume Spexib 150mg Capsule","text":"

Take the capsules at about the same time each day. The recommended dose is 450mg, taken once daily with food. Swallow the capsules whole and do not crush, chew, dissolve, or open the capsules. Your physician will choose the dosage and administration frequency based on the medical condition because it differs for each person.

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It is unsafe to breastfeed while taking Spexib 150mg because it can cause toxicity to the baby. Consult your physician for more information.

","imageUrl":"https://assets.mrmed.in/others/file-1674132409667-45039420-Breatfeeding.jpg"},{"id":"87fc7431-73a4-4914-b401-d08a5ddbc62f","advice":"Alcohol","tag":"Consult your doctor","description":"

It is unknown whether it is safe to consume alcohol with Spexib 150mg. Please consult your doctor for more information.

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Inform your physician about any underlying liver disorders before taking Spexib 150mg, as this medication should be used with caution in liver disease patients. Consult your physician before taking this medicine.

","imageUrl":"https://assets.mrmed.in/others/file-1674132424807-417765861-Liver.jpg"},{"id":"40d845f0-78b4-4543-9c37-01a416266fd3","advice":"Lungs","tag":"Consult your doctor","description":"

Inform your physician about any underlying lung disorders before taking Spexib 150mg, as this medication should be used with caution in such conditions. Consult your physician before taking this medicine. Notify your doctor if you experience any lung-related symptoms, such as difficulty breathing.

","imageUrl":"https://assets.mrmed.in/others/file-1674132427859-226731771-Lungs.jpg"},{"id":"d367e702-97f0-483f-8ab0-255fd5a003e6","advice":"Driving","tag":"unsafe","description":"

It is unsafe to drive while taking Spexib 150mg because this medicine might cause vision problems and tiredness, so avoid driving and operating machinery during this treatment.

","imageUrl":"https://assets.mrmed.in/others/file-1674132431331-421990512-Driving.jpg"},{"id":"17a6a3fc-d9ed-4de1-8b1b-cf1081777df3","advice":"Pregnancy","tag":"unsafe","description":"

This medicine is unsafe for use during pregnancy. Hence, check with your physician if you are pregnant or think you might be pregnant before taking this medicine. Use effective contraception methods.

","imageUrl":"https://assets.mrmed.in/others/file-1674132401469-949914510-Pregnancy.jpg"}]}},{"id":"267b3154-1d34-4dfa-9283-f0dae39038a4","type":"PARA","position":8,"content_placement":1,"data":{"heading":"Side Effects of Spexib 150mg Capsule","text":"

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.

Serious

Increase urination
Irregular heartbeat
Cough with or without mucus
Fever Chest pain
Difficulty in breathing or swallowing
Swelling in the face, lips, tongue or throat
Severe itching in the skin with bumps or red rash
Right side abdomen pain
Bleeding and Bruises

Common

Decreased appetite
Anemia
The lower level of phosphate
Diarrhea
Nausea
Vomiting
Stomach ache
Constipation
Skin rash

"}},{"id":"1120df53-3a94-4ece-9053-a58f04cdc0ca","type":"PARA","position":9,"content_placement":1,"data":{"heading":"Word of Advice","text":"

Your doctor may perform an electrocardiogram to check your heart functioning level. It is important to take Spexib 150mg daily as long as your doctor prescribes it. Use highly effective contraception during and after the treatment for three months. Your doctor may conduct a blood test every two weeks of the first three months to monitor liver, blood, and pancreas function. If you vomit after taking the capsule, do not take another one. Notify your doctor if you experience any side effect symptoms, as your doctor may change the dosage of this medicine or give additional medicine to reduce the effect of the side effects.

"}},{"id":"c655c49f-716e-4066-86df-20ae6b0a2e56","type":"FAQ","position":10,"content_placement":2,"data":{"heading":"FAQs about Spexib 150mg Capsule","faq_list":[{"id":"86ab90ab-63c3-4a40-9153-72cb13620db9","question":"

Can Spexib 150mg cause liver damage?

","answer":"

Spexib 150mg may cause liver function abnormalities, indicating liver damage. It is important to have regular blood tests to monitor your liver function while taking this medicine. If you experience symptoms of liver damage, such as jaundice or abdominal pain, you should contact your doctor immediately.

"},{"id":"373c7865-483a-4f84-a4d5-c55d570fd96d","question":"

Does Spexib 150mg cure cancer?

","answer":"

Spexib 150mg is not a cure for cancer, but it can help to slow down or stop the growth and spread of cancer cells, improving the overall survival and quality of life of patients with certain types of cancer.

"},{"id":"deab7700-a964-49dd-888b-05810dd125bc","question":"

Who should not take Spexib 150mg?

","answer":"

Spexib 150mg should not be taken by pregnant or breastfeeding women or by people with certain medical conditions such as severe liver or lung, heart disease, a history of pancreatitis, diabetes, or a prolonged QT interval.

"},{"id":"3da18574-0fad-4d57-a996-f326362ee29d","question":"

Will there be a reduction of RBC (anemia) while taking Spexib 150mg?

","answer":"

Yes, one of the common side effects of this medicine is anemia. Spexib 150mg can cause anemia by suppressing the production of red blood cells.

"},{"id":"af0b470f-fc23-414a-9b13-b2461409ce34","question":"

Why are there low phosphate levels in the blood while taking Spexib 150mg?

","answer":"

The exact mechanism by which Spexib 150mg causes hypophosphatemia (low level of phosphate) is not fully understood, but it is thought to be related to the inhibition of certain enzymes involved in phosphate transport and metabolism in the body.

"}]}},{"id":"05be4dc3-f45c-4c4f-ab88-b4a88de28360","type":"PARA","position":11,"content_placement":3,"data":{"heading":"Fact Box of Spexib 150mg Capsule","text":"

Molecule name: Ceritinib	Therapeutic class: Antineoplastic drug
Pharmacological class: Anaplastic Lymphoma Kinase Inhibitors	Indication: Anaplastic lymphoma kinase (ALK) positive non-small cell lung cancer (NSCLC)

"}},{"id":"655e2d15-6d01-4cfa-8f9c-d60bd41f40d5","type":"PARA","position":12,"content_placement":3,"data":{"heading":"References","text":"

Bing Xia, Roy S. Herbst, Management of Advanced Non–Small Cell Lung Cancer: Noncurative Intent Treatment, Lung Cancer: A Practical Approach to Evidence-Based Clinical Evaluation and Management, 2018, 99-115.
Novartis Pharmaceuticals, Electronic Medicines Compendium(EMC), [Revised on Jan 2020] [Accessed on 26th April 2023] https://www.medicines.org.uk/emc/files/pil.7109.pdf
Novartis Pharmaceuticals, Central Drugs Standard Control Organisation, [Revised on 22nd Jan 2019] [Accessed on 26th April 2023], https://cdsco.gov.in/opencms/resources/UploadCDSCOWeb/2018/UploadPrescribingInfo/9Spexib 150mg.pdf

"}},{"id":"95698ca8-42cc-4ea4-8519-ba731e718df0","type":"DISCLAIMER","position":13,"content_placement":5,"data":{"heading":"Disclaimer","text":"

MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.

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