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Synvisc ONE Injection

Prescription Required


Salt Composition : Hylan Polymer A&b G-f 20

Manufacturer : SANOFI INDIA LTD

Origin of Medicine : France

MRP: 21449.99
Price :18855
You Save :2595 (12%)

1 Prefilled Syringe(s) Of 6ml

Prepaid Only. Non-Returnable

Delivery By -

Introduction to Synvisc One Injection

Synvisc one injection are derivative of hyaluronan, a sodium salt of hyaluronic acid. Hyaluronan is a component of synovial fluid, a fluid responsible for viscosity in joints that helps in mobility. Synvisc one injection polymer A&B G-F 20 is given as an intra-articular injection for patients with knee osteoarthritis. It is used to decrease the pain and discomfort associated with knee disorders by acting as a temporary replacement of synovial fluid, which is helpful for patients who use the affected knee regularly. It may be used alone or in combination with other medicines. Do not consume this medication if you are allergic to Proteolytic or its ingredients.

Tell your doctor if you are pregnant, planning to get pregnant, or breastfeeding before taking this medicine. Before taking this medicine, talk to your doctor about all the medicines you are taking recently, including supplements and herbal medicines. Notify your doctor if you have a knee joint infection, skin disease or infection on the injection site, or systemic bleeding disorders. Before receiving Synvisc one, tell your doctor if you have severe knee inflammation, lymphatic or venous stasis (swollen or inflamed) in the leg to be injected, and chondrocalcinosis (presence of CPP (calcium pyrophosphate dihydrate) crystals in and around the joints). Limited information is only available on the usage of children. In elders, this medicine should be used cautiously. Consult your doctor for more information. 

Uses of Synvisc One Injection

  • Osteoarthritis of the knee

Therapeutic Effects of Synvisc One Injection

Synvisc one works by enabling a process called viscosupplementation; in viscosupplementation, the cartilage cells are protected from physical and chemical damage by restoring the physiological conditions of the tissues in the joints. This, in turn, eases pain and discomfort and allows more extensive movement of the joints.

Interaction of Synvisc One Injection with other drugs

Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications, such as blood thinners and antibiotics, may interact with Proteolytic and cause undesirable side effects.

More Information about Synvisc One Injection

  • Protect the injection from light and moisture.
  • Keep out of sight and reach of children and pets.
  • Store in original packaging at room temperature below 30°C.

How to consume Synvisc One Injection

Synvisc one will be administered to you by a doctor or other healthcare professional in the knee. Your doctor will decide the dose, route of administration, and duration of the therapy based on your disease status, severity, and other factors such as body weight, other disease conditions, and age. Do not self-administer the injection. 

Safety Advices for Synvisc One Injection

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Report to your doctor if you are pregnant or think you may be pregnant or planning for the pregnancy before starting the treatment. Because it is unknown whether Synvisc one is safe to administer in such conditions. 

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Breast Feeding


It is unknown whether Synvisc one is safe to administer in breastfeeding patients. Therefore, talk with your doctor to get more information. Inform your doctor if you are breastfeeding. 

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It is unknown whether Synvisc one is safe for patients with lung problems. Inform your physician if you have any lung disease before starting the treatment. Contact your doctor if you experience any lung-related symptoms.

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Inform your physician if you have liver problems because it is unknown whether the consumption of Synvisc one is safe. Report to your doctor if you experience any liver-based symptoms. 

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It is unknown whether consuming alcohol while taking a Synvisc one tablet is safe. Please speak with your physician.

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Talk to your doctor about whether consuming Synvisc one is safe for driving. 

Side Effects of Synvisc One Injection

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.


  • Hypersensitivity reactions (anaphylactic shock, anaphylactoid reaction, angioedema)


  • Joint pain and inflammation
  • Pain in the injection site

Word of Advice

Notify your doctor about all your underlying medication conditions. It is curious to tell your physician if you are pregnant or planning to get pregnant or breasting. Report to your doctor if you experience any side effects or new symptoms, and also mention if you take any other medicine before starting the treatment. Do not take this medication if you are allergic to Synvisc one or its other ingredient. 


Q 1. What is Synvisc one?

Synvisc one is a medical device used to treat knee pain caused by osteoarthritis. It is a viscosupplementation therapy that injects a gel-like substance into the knee joint to cushion and lubricate.

Q 2. How long does the effect of Synvisc one?

The effect of Synvisc one can vary from person to person, but it typically lasts for several months. Some people may experience longer-lasting pain relief, while others may require additional injections to maintain the benefits.

Q 3. Who is contraindicated to Synvisc one?

Suppose you are allergic to Synvisc one or its ingredient if you have infections or skin diseases in the area where the injection will be given. It is important to discuss any allergies or medical conditions with a healthcare professional before receiving treatment with Synvisc one.

Q 4. What should I do if I experience any side effects?

Contact your doctor immediately.

Q 5. My friend has a liver condition. Is that okay if he consumes Synvisc one?

There is only limited information available about Synvisc one usage in liver patients. So, notify your doctor before starting the treatment, not only about the live condition but also about all their underlying medical conditions that must be reported to your physician.

Fact Box of Synvisc One Injection

Molecule name: Hylan Polymer A&B G-F 20

Therapeutic class: Osteoarthritis 

Pharmacological class: Intra-Articular Agents

Indications: Osteoarthritis of the knee


  1. Genzyme Biosurgery, Genzyme Europe B.V, Package insert, [Revised on Sep 2014] [Accessed on 3rd May 2023]


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